KEGG   Rattus norvegicus (rat): 54314
Entry
54314             CDS       T01003                                 
Symbol
Tpo
Name
(RefSeq) thyroid peroxidase precursor
  KO
K00431  thyroid peroxidase [EC:1.11.1.8]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00350  Tyrosine metabolism
rno01100  Metabolic pathways
rno04918  Thyroid hormone synthesis
rno05320  Autoimmune thyroid disease
Module
rno_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    54314 (Tpo)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    54314 (Tpo)
 09160 Human Diseases
  09163 Immune disease
   05320 Autoimmune thyroid disease
    54314 (Tpo)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8  iodide peroxidase
     54314 (Tpo)
SSDB
Motif
Pfam: An_peroxidase EGF_CA Sushi EGF_3 FXa_inhibition EGF Plasmod_Pvs28 cEGF
Other DBs
NCBI-GeneID: 54314
NCBI-ProteinID: NP_062226
RGD: 3900
Ensembl: ENSRNOG00000004646
UniProt: F1LN48
Position
6:complement(52425998..52495793)
AA seq 914 aa
MRTLGAMAVMLVVMGTAIFLPFLLRSRDILGGKTMTSHVINVVETSQLLVDNAVYNTMKR
NLKKRGVLSPAQLLSFSKLPESTSGAISRAAEIMETSIQVMKREQSQFSTDALSADILAT
IANLSGCLPFMLPPRCPDTCLANKYRPITGVCNNRDHPRWGASNTALARWLPPVYEDGFS
QPRGWNPNFLYHGFPLPPVREVTRHLIQVSNEAVTEDDQYSDFLPVWGQYIDHDIALTPQ
STSTAAFWGGVDCQLTCENQNPCFPIQLPSNSSRTTACLPFYRSSAACGTGDQGALFGNL
SAANPRQQMNGLTSFLDASTVYGSSPGVEKQLRNWSSSAGLLRVNTLHLDSGRAYLPFAS
AACAPEPGAPHANRTPCFLAGDGRASEVPALAAVHTLWLREHNRLATAFKAINTHWSANT
AYQEARKVVGALHQIITMRDYIPKILGPDAFRQYVGPYEGYNPTVNPTVSNVFSTAAFRF
GHATVHPLVRRLNTDFQDHTELPRLQLHDVFFRPWRLIQEGGLDPIVRGLLARPAKLQVQ
EQLMNEELTERLFVLSNVGTLDLASLNLQRGRDHGLPGYNEWREFCGLSRLETPAELNKA
IANRSMVNKIMELYKHADNIDVWLGGLAEKFLPGARTGPLFACIIGKQMKALRDGDRFWW
ENSHVFTDAQRQELEKHSLPRVICDNTGLTRVPVDAFRIGKFPQDFESCEEIPSMDLRLW
RETFPQDDKCVFPEKVDNGNFVHCEESGKLVLVYSCFHGYKLQGQEQVTCTQNGWDSEPP
VCKDVNECADLTHPPCHSSAKCKNTKGSFQCVCTDPYVLGEDEKTCIDSGRLPRASWVSI
ALGALLIGGLASLSWTVICRWTHADKKSTLLITERVTTESGFRKSQESGISPQKAEVQDA
EQEPAYGSRVLLCE
NT seq 2745 nt   +upstreamnt  +downstreamnt
atgagaacacttggagctatggcagtaatgctggttgtgatgggaactgcaattttcctc
cctttcctcctgagaagcagagacatcttgggggggaagactatgacatcccatgttatc
aatgttgtagaaacgagccagcttctggtggacaatgcagtctacaacaccatgaaaaga
aacctcaagaaaaggggagtcctttctccagcccagcttctctctttctccaagctgcca
gagtccaccagtggagctatttcccgagcagcagagatcatggaaacatcaatacaagtc
atgaaacgtgaacaatcacagttctccacggatgcactatcagcagacatcctggccaca
attgccaacctgtcaggatgcttgcctttcatgctgccaccgagatgtcctgacacctgc
ctggcaaacaagtaccggcccatcacaggggtgtgcaacaacagagatcaccccagatgg
ggagcctccaacacagccctagcaagatggctgcctcctgtctacgaagatggtttcagt
cagcccagaggctggaaccctaatttcttataccatggcttcccactgcccccggtacgg
gaggtgacaagacacctcattcaagtttcaaatgaggctgtgactgaagatgaccagtac
tctgattttctgccggtgtggggacagtacatcgatcatgacattgctctcacaccacag
agcaccagcacagcagccttctggggaggtgtcgactgccagttgacctgtgagaaccaa
aacccctgcttccccatacagcttccctcaaactcctcacggaccactgcatgcctacct
ttctaccgctcctcagccgcctgtggcactggggaccaaggagcactctttggcaacctg
tctgcagccaatccgaggcagcagatgaatggcttgacctccttccttgatgcttccacg
gtgtatggcagctccccaggtgttgagaagcagttgcgcaactggagcagctctgcaggg
ctgctgcgtgtcaacaccctccacctagactctggccgtgcctacctgcccttcgcatca
gccgcctgtgctccagagcctggtgctccacacgccaaccgcacgccctgcttcctggct
ggtgatggccgcgccagcgaggtccccgccctggcagcagtgcacaccttgtggctgcgc
gagcacaaccgcctggctacagctttcaaagccatcaacacacattggagcgccaacact
gcctaccaggaggcacgcaaggtggtaggggcattgcaccagatcatcaccatgagggat
tatatccccaagatcctgggtcccgatgccttcaggcagtatgtgggcccctatgaaggc
tataaccccacggtgaaccctactgtgtccaacgtcttctctactgctgccttccgcttt
ggccatgccacagtccatccactggtgagacgactaaacacagacttccaggaccacaca
gagctccccaggctgcagctgcacgacgtcttcttcaggccctggaggcttatccaggaa
ggtggtttggatccaatagtaagaggcctcctggcaagaccagccaagctgcaagtacag
gagcaactgatgaatgaggaactgaccgagaggctctttgtgttgtctaatgtgggcacc
ttggatctggcatcactgaacttgcagaggggccgggaccacggcttaccaggctacaat
gagtggagagagttctgtggcttgtcacgcctggagacaccagctgagctgaacaaggcc
attgccaacagaagcatggtcaacaagataatggagttatacaagcatgctgacaacatt
gatgtctggttgggaggcctggctgaaaagttcttaccgggagcccgcaccggtcctctg
tttgcatgtatcattgggaagcagatgaaggctctgagggatggggacaggttttggtgg
gagaacagccatgtcttcacagacgctcagaggcaggaactggaaaagcattcactacct
cgggtcatctgtgacaacaccggcctcaccagagtacctgtggatgccttccgtattgga
aagttcccccaggactttgaatcctgtgaggaaatccctagcatggacctcagactgtgg
agggagaccttcccacaagacgacaagtgtgtcttcccagagaaggtggacaatgggaac
tttgtgcactgtgaagaatctgggaagctggtactggtgtattcctgtttccatggatac
aagctgcaaggccaggagcaggtcacatgtacccagaatggatgggactcagagcctcct
gtctgtaaagatgttaatgagtgtgcagatctgacacacccaccttgccactcctccgca
aagtgcaagaacaccaagggaagcttccagtgtgtgtgcacagacccctacgtgctaggt
gaggatgagaagacctgcatagattctggcaggctacctcgggcatcctgggtctccatt
gcattgggtgcacttctcattggtggtttggccagtctcagctggactgtaatttgcagg
tggacacatgctgataagaagtccacattgctgatcaccgagagagtgaccacggagtca
ggattcagaaagagtcaggagagtgggatttcaccacaaaaggccgaggttcaagatgct
gaacaggaaccggcttatggatccagagtcctcctgtgtgaatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (8)   
   Pfam (8)   
All databases (46)   

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