KEGG   Rattus norvegicus (rat): 56761
Entry
56761             CDS       T01003                                 
Symbol
Notch3
Name
(RefSeq) neurogenic locus notch homolog protein 3 precursor
  KO
K20995  Notch 3
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01522  Endocrine resistance
rno04330  Notch signaling pathway
rno04371  Apelin signaling pathway
rno04658  Th1 and Th2 cell differentiation
rno04919  Thyroid hormone signaling pathway
rno05165  Human papillomavirus infection
rno05200  Pathways in cancer
rno05206  MicroRNAs in cancer
rno05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    56761 (Notch3)
   04371 Apelin signaling pathway
    56761 (Notch3)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    56761 (Notch3)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    56761 (Notch3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    56761 (Notch3)
   05206 MicroRNAs in cancer
    56761 (Notch3)
  09162 Cancer: specific types
   05224 Breast cancer
    56761 (Notch3)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    56761 (Notch3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    56761 (Notch3)
SSDB
Motif
Pfam: EGF hEGF EGF_CA Ank_2 Ank Notch NODP Ank_4 NOD Ank_3 EGF_2 Ank_5 EGF_3 JAG1-like_EGF2 cEGF DL-JAG_EGF-like FXa_inhibition
Other DBs
NCBI-GeneID: 56761
NCBI-ProteinID: NP_064472
RGD: 620761
Ensembl: ENSRNOG00000004346
UniProt: Q9R172
Position
7:complement(11783550..11834585)
AA seq 2319 aa
MGPGARGRRRRRRLMALPPPPPPMRALPLLLLLLAGLGAAAPPCLDGSPCANGGRCTHQQ
PSREAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGVARFSCRCLRGFRGPDCS
LPDPCFSSPCAHGAPCSVGSDGRYACACPPGYQGRNCRSDIDECRAGASCRHGGTCINTP
GSFHCLCPLGYTGLLCENPIVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVD
DCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGGH
SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN
PCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQ
CGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTFCEVDIDECQSSPC
VNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE
GTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCL
DLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEI
NECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPVNHPCAHKPCSHGVCHDAPGGFQC
VCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFHCTCAPGFQGHQCEVLSPCTPS
LCEHGGHCESDPDQLTVCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGSFRCICH
GGYTGPFCDQDIDDCDPNPCLNGGSCQDGVGSFSCSCLSGFAGPRCARDVDECLSSPCGP
GTCTDHVASFTCTCPPGYGGFHCETDLLDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGTH
CQYKVDPCFSRPCLHGGICNPTHSGFECTCREGFTGNQCQNPVDWCSQAPCQNGGRCVQT
GAYCICPPEWSGPLCDIPSLPCTEAAAHMGVRLEQLCQAGGQCIDKDHSHYCVCPEGRMG
SHCEQEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYSGDSCEDDVDECASQPCQNGGSCI
DLVAHYLCSCPPGTLGVLCEINEDDCGPGPSLDSGLRCLHNGTCVDLVGGFRCNCPPGYT
GLHCEADINECRPGTCHAAHTRDCLQDPGGHFRCICLPGFTGPRCQTALFPCESQPCQHG
GQCRPSLGRGGGLTFTCHCVQPFWGLRCERVARSCRELQCPVGIPCQQTARGPRCACPPG
LSGPSCRVSRASPSGATNTSCAATPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSAA
PEVPEEPRCPRAACQAKRGDQNCDRECNSPGCGWDGGDCSLNVDDPWRQCEALQCWRLFN
NSRCDPACSSPACLYDNFDCYSGGRDRTCNPVYKKYCADHFADGRCDQGCNTEECGWDGL
DCASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDARGQAMVFPY
HRPSPGSESRVRRELGPEVIGSVVMLEIDNRLCLKSAENDHCFPDAQSAADYLGALSAVE
RLDFPYPLRDVRGEPLEPPEQSVPLLPLLVAGAVFLLVIFVLGVMVARRKREHSTLWFPE
GFALHKDIAAGHKGRREPVGQDALGMKNMTKGESLMGEVATDWNDSECPEAKRLKVEEPG
MGAEEPVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASF
CGGALEPMPAEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRL
LDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAV
EGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFL
AAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPSGPHG
LGPLLCPPGAFLPGLKAVQSGTKKSRRPPGKTGLGPQGTRGRGKKLTLACPGPLADSSVT
LSPVDSLDSPRPFGGPPASPGGFPLEGPYATTATTVSLAQLGASRAGPLGRQPPGGCVLS
LGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGSQLLNPATPVSPHERPPPYLAAPGHGE
EYPAAGTHSSPTKARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSDSTPSPATATSA
TAAGALPAQPHPISVPSLPQSQTQLGPQPEVTPKRQVMA
NT seq 6960 nt   +upstreamnt  +downstreamnt
atggggccgggggcccggggccgccgccgccgtcgtcgcctgatggccctgccaccgcca
ccaccgcccatgcgggcgctgcccctgctgctgctgctgctagcggggctgggggctgca
gcacccccttgtctggatggaagcccatgtgcaaatggaggtcgttgcacccaccagcag
ccctcccgggaggctgcttgcctgtgcctgccaggctgggtgggtgagcggtgccagctg
gaagacccttgccactctggcccctgtgccggccgaggcgtttgccagagttcagtggtg
gcgggcgtcgcccggttctcctgtcgttgtctccgtggcttccgaggcccagactgctcc
ctgccagacccctgcttcagcagcccctgtgctcacggtgccccctgctcagttgggtcg
gatggccgatatgcctgtgcctgcccacctggctaccagggtcgcaactgccgaagcgac
atagatgagtgccgagctggtgcgtcttgccgtcacggtggtacctgcatcaatacaccc
ggatccttccactgcctgtgtccacttggctatacagggctgctgtgtgaaaaccccata
gtgccctgcgccccttccccatgccgtaatggtggcacctgtaggcagagtagtgatgtc
acatatgactgtgcttgtcttcctggcttcgagggccagaactgtgaagtcaatgtggat
gactgtcctggacatcggtgtctcaatgggggaacgtgtgtggatggtgtcaatacttat
aactgccagtgccctcctgagtggacaggccagttctgcacagaagatgtggatgagtgc
cagttgcagcccaacgcttgccacaatgggggcacctgcttcaacctactgggcggccac
agctgcgtatgcgtcaacggctggacgggcgagagctgcagtcagaatattgatgactgt
gctacagccgtttgcttccatggggccacttgccatgaccgtgtggcctctttctattgt
gcctgccctatggggaagacaggcctcttgtgtcatctggatgatgcatgtgtcagcaac
ccctgccatgaagatgctatctgtgacacaaaccctgtgagtggtcgggccatctgcacc
tgtccacccggcttcaccggaggggcgtgtgaccaggatgtggatgagtgctctattggt
gctaacccctgtgaacatttgggtcggtgcgtgaacacacagggctcattcttgtgccag
tgtggccgtggctatactggacctcgctgtgagactgatgtcaatgagtgtctgtctggg
ccctgccgcaaccaggccacgtgtcttgaccgaattggccagttcacttgcatctgcatg
gcaggcttcacaggaaccttctgtgaggtggacattgatgaatgtcagagcagcccatgt
gtcaatggtggtgtctgcaaggatagagtcaatggcttcagctgcacctgcccatcagga
ttcagtgggtccacgtgtcagctggatgtggatgaatgtgcaagcactccttgccggaac
ggtgccaagtgtgtggaccagcctgacggctatgagtgtcgctgtgcagagggctttgag
ggcaccctgtgtgagcgaaacgtggacgactgctctccggatccctgtcaccacgggcgg
tgtgtcgacggcattgctagcttctcatgcgcttgtgcgccaggctacacgggcatacgc
tgcgagagccaggtggatgagtgccgcagccagccctgccgatacgggggcaaatgtcta
gacttggtggacaagtacctctgccgctgtcctcccggaaccacaggtgtgaactgcgaa
gtcaacatcgatgattgcgccagcaacccctgtacctttggagtttgccgtgatggcatc
aaccgctatgattgtgtctgtcagcctggattcacagggcccctctgcaacgtggagatc
aatgagtgtgcatccagcccatgtggagagggtggctcctgtgtggacggggaaaatggc
ttccactgcctctgcccacctggctccctgcctccactctgcctacctgtgaatcacccc
tgtgcccacaagccctgtagtcatggagtctgccacgatgcaccaggcgggtttcaatgt
gtgtgcgagcccggttggagtggccctcgttgcagccagagcctggctccagatgcctgt
gagtcccagccctgccaggctggtggcacctgcaccagtgatggaataggcttccactgt
acctgtgcccctggattccagggtcatcaatgtgaggtgctgtccccctgcactccaagt
ctctgtgagcacggaggccactgtgagtctgaccctgaccagctgactgtctgttcctgt
cctccaggctggcaaggccctcgatgccagcaggatgtggatgaatgtgctggtgcctca
ccttgtggcccccatggtacctgcaccaacctgccagggagcttcaggtgcatctgccat
ggaggatacactggccctttctgtgatcaggacattgacgactgtgaccccaacccgtgc
ctcaatggtggctcctgccaggatggtgtgggctccttttcctgttcttgcctcagtggc
tttgctggtcctcgctgtgctcgggatgtggatgaatgtctgagcagtccctgtggccct
ggcacctgcactgatcatgtagcctctttcacctgtacctgtccacctggctatggaggc
ttccactgtgagactgacttgctggactgcagccccagttcctgtttcaatggagggacc
tgtgtggatggcgtgaactccttcagctgtctgtgtcgtcctggctacacaggcacacat
tgccaatataaggttgacccctgcttctcccggccctgtctacatgggggcatctgcaac
cccacccactcaggatttgaatgcacctgccgggagggcttcactgggaatcagtgtcag
aacccagtggactggtgcagccaggcaccctgtcagaatgggggtcgctgtgtccagact
ggggcttactgcatctgtccgcctgaatggagtggccccctgtgcgacataccaagccta
ccctgcacggaggctgcagcccacatgggggtgcggttggagcagctgtgtcaggcgggt
ggccagtgcatagacaaggaccactcccactactgtgtgtgtccggagggccgtatgggt
agtcactgcgaacaggaggtggatccctgcacagcccagccttgccagcatgggggcacc
tgccgtggttacatgggcggctatgtgtgtgagtgtccagccggctactctggtgacagt
tgtgaggatgatgtggatgagtgcgcttcccagccctgccagaatggaggctcctgtatt
gatcttgtggcccactatctctgctcctgtccccctggcacactgggagttctctgtgag
atcaatgaggatgactgtggcccaggcccatccttggactcaggcctccggtgcctacac
aacggcacctgtgtggacctggtgggtggcttccgctgtaactgtcccccagggtacaca
ggtctgcactgtgaggcggacatcaatgagtgccgacccggcacctgtcatgcagcacat
acccgggactgcctacaagatccaggtgggcacttccgctgcatctgtctccctggcttc
acagggcctcgatgtcagactgctctgttcccctgtgagtcccaaccgtgtcagcatgga
ggccagtgccgtcccagcctaggccgtggaggtgggctgaccttcacctgtcactgtgtc
cagccattctggggtctgcgttgcgagcgggtggcacgctcctgccgggagctgcagtgc
ccagtgggtatcccatgccagcagacagcccgtgggccgcgctgtgcttgtcctcccggg
ctgtctgggccctcctgccgggtttctagggcgtcaccctctggagctactaacaccagc
tgcgctgctactccttgtctgcatgggggctcctgcctacctgtacagagtgtccctttc
ttccgctgtgtatgcgctccgggctggggtggcccgcgttgcgagaccccttccgcagcc
cctgaggtccctgaggagccacggtgcccgcgagccgcctgtcaggccaagcgaggggac
cagaactgcgaccgtgagtgcaacagcccaggctgtggctgggacggcggtgactgctcg
ctgaatgtggacgacccctggaggcagtgtgaggcactgcagtgctggcgtctcttcaac
aacagccggtgcgatccagcctgcagctctcctgcctgcctctatgacaactttgactgc
tactctggtggccgcgaccgcacctgcaacccggtttataagaagtactgcgccgaccac
tttgcagatggccgttgtgaccagggctgtaacaccgaggagtgtggctgggatgggctg
gactgtgccagtgaggtcccggcccttttggcccggggggttctggtcctcacagttctt
ctgcctcctgaagagttgcttcgctctagtgccgacttcctgcagcgactcagcgctatt
ctgcgcacctcgctgcgcttccgcctggatgcacgtggccaagccatggtctttccctac
caccggccaagtcctggctccgaatcccgggttcgtcgtgagcttggcccagaggtgatc
ggctctgtagtgatgctggagattgacaaccggctctgtctgaagtcagcggagaacgac
cactgcttccctgacgcccagagtgctgccgactacctgggagccttgtcggcagtggag
cggcttgatttcccatacccactacgggatgtgcgaggagagcccttggagcctccagag
cagagcgtgccactgctgccgctgctggtggcaggggctgtctttctgctggtcatcttc
gtcctgggtgtcatggttgccaggcgcaagcgagagcacagcaccctctggtttcctgag
ggttttgcattacacaaggacatagctgctggccacaagggccggagggagcccgtggga
caagacgcactgggcatgaagaacatgaccaagggtgagagtctgatgggggaggtggcc
acagactggaatgactcagaatgcccagaggccaagagactgaaggtagaggagccaggc
atgggggccgaggagcccgtggactgtcgccagtggacccaacaccacctggttgctgcc
gatatccgtgtggcaccagccatggcactgactccacctcagggagatgcagatgccgat
ggcatggatgtcaacgtacgagggcctgatggcttcaccccacttatgctggcctcgttc
tgtgggggagccctggagccgatgccagctgaggaggatgaggccgatgacacgtcagcc
agcattatatcagatctgatctgccaaggagcccagctcggggcacgaactgaccgaact
ggcgagaccgccctgcatttggccgcccgatatgctcgagccgatgcggccaagcggcta
ctggatgctggggcagacaccaacgcccaggatcattctggccgcacccctctgcacacc
gcagtgacagctgatgcccagggtgtcttccagattctcatcaggaaccgctccactgac
ctggatgcccgaatggcagatggctctactgcattgatcctggcagcccgcctggcggtg
gagggaatggtggaagagctcatcgccagccacgccgatgtcaatgcagtggatgagctc
gggaaatcggccttacactgggctgcagccgtgaacaatgtggaggctaccttggccctg
ctgaaaaatggagccaacaaggacatgcaggacagcaaggaggagactccactgttcttg
gccgcccgtgagggcagctatgaggctgccaagctgctgctggatcattttgccaaccgg
gagatcacagatcacttggacaggctgccccgggatgtggcccaggagcggctgcaccag
gacattgtgcggttgctggaccagcccagtggcccccgaagtccctctggtccccatggc
ttggggccattgctctgcccaccaggagccttccttcctggcctcaaagcggtgcagtct
gggaccaagaagagcaggaggccacctggcaagactgggctggggccccagggaactcgg
ggtcggggcaagaagctgacactggcctgtccaggccctctggcagacagctctgtcaca
ctgtcaccagtggactcgctggactcaccacggcctttcggtgggccccctgcttcccct
ggaggcttccccttggagggtccctatgccaccacagccaccacggtgtccttggcacag
ctgggtgcaagtcgggcgggtcctctggggcgccagcctcctgggggctgtgtgctcagc
cttggtttgctcaaccctgtggctgttccccttgactgggcccggctgcctccacctgcc
cctccagggccctcattcctgctgcccctggctccgggatcccagctgctcaacccggca
accccagtttctccccatgagcggcccccaccctacctggctgctccaggacatggagag
gaataccctgcagcagggacccacagcagccccacaaaggcccgcttcctgcgggttccc
agcgagcatccttatttgaccccatctcctgagtccccagagcactgggccagcccgtcc
cctccctccctctcagactggtccgactcaacgcctagtccagcaactgctaccagtgcc
acagccgctggagccctgcctgctcaaccacaccccatatctgttccctccctccctcag
tcccagactcagctggggccccagccagaagtaacccccaagaggcaggtgatggcctaa

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (9)   
   KEGG PATHWAY (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (17)   
   Pfam (17)   
All databases (42)   

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