KEGG   Rattus norvegicus (rat): 59077
Entry
59077             CDS       T01003                                 
Symbol
Grk4
Name
(RefSeq) G protein-coupled receptor kinase 4
  KO
K08291  G protein-coupled receptor kinase [EC:2.7.11.16]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04062  Chemokine signaling pathway
rno04144  Endocytosis
rno05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    59077 (Grk4)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    59077 (Grk4)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    59077 (Grk4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    59077 (Grk4)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.16  G-protein-coupled receptor kinase
     59077 (Grk4)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: AGC group
  GRK family [OT]
   59077 (Grk4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr RGS Kinase-like Pkinase_fungal
Other DBs
NCBI-GeneID: 59077
NCBI-ProteinID: NP_075217
RGD: 61858
Ensembl: ENSRNOG00000011847
UniProt: P70507 A6IK17
Position
14:complement(80230699..80305292)
AA seq 575 aa
MELENFMANTLLLKARQGFTKKTGRSKKWRELLKLPPVSMCSDLRHSIEKDFSSLCDQQP
IGRLLFRQFCNTKPDLKRCIEFLDAAAEYEVTIEEEQREFGLSIYSRFFKENSEVSLPQI
PPDLVKECKCNLKQSSPSQNVFQDCAGVIYKYLSEKPFEEYQESTYYNRFLQWKWLERRP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEK
LHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGNPGFEEQRAVFYAAELCCGLE
DLQRERIVYRDLKPENILLDDHGHIRISDLGLALEIPEGEMVRGRVGTVGYMAPEIISHE
KYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREEMERRVKTETEEYSERFSENAKSIC
SMLLTKDPSKRLGCQSDGASAVKQHPIFKDINFSRLEANMLDPPFCPDPEAIYCKDILDI
GQFSVVKGVNLDTNDEIFYTQFATGCVTIPWQNEMIESGCFKDLNEYEDKGLSPLEKHKI
CSCILRPKRNFFHRLFRRAACLNIAHSEEREPTEH
NT seq 1728 nt   +upstreamnt  +downstreamnt
atggaactggagaacttcatggccaacactttgttgctgaaggctcgtcaaggatttacc
aaaaagactggtcgcagtaaaaagtggagagagctcctgaagttgcccccagtcagcatg
tgcagtgacttacgacactccatcgaaaaggattttagcagtctttgtgaccaacagcca
atcggaagacttcttttcagacaattctgtaatacgaaaccagatctaaagaggtgcatt
gaattcttggatgcagcggcagagtatgaagttaccatcgaagaggaacaaagagaattt
ggactatccatctacagtagattcttcaaagagaattcagaagtctccttaccacagata
cctccagatcttgtgaaggagtgtaaatgcaatctgaagcagagttctccctctcaaaat
gtgttccaggactgtgctggagttatctataagtatttgagtgaaaaaccatttgaagaa
taccaagagagtacatactataatcgatttttacaatggaaatggctagaaaggcgtcca
gtaacaaagaacacattcagacaatacagagttttaggaaaaggcggatttggagaggtt
tgtgcctgtcaagtgcgagctacaggaaaaatgtatgcctgcaaaaaactagaaaaaaaa
agaataaagaagaggaaaggtgaagccatggctctgaatgaaaaaagaatcttagaaaaa
ttgcatagtagatttgtagttagtttagcctacacttatgaaaccaaggatgctttgtgt
ttggtgctaaccattatgaatggaggggatttgaagtaccacatttacaacctgggcaat
cctggctttgaggagcagagagctgtgttctatgctgcagagctgtgctgtggcttggaa
gatttacagagggaaagaattgtatacagagacctaaaaccagagaatatcctccttgat
gatcatggacacatccgaatttcagatcttggtctagctctggaaatcccagaaggggag
atggttcgaggaagagttggtactgttggctacatggctccagaaattatcagtcatgaa
aagtatacatttagtcctgattggtggggacttggctgtctgatatatgaaatgattgcg
ggacattctccattcagaaaatataaagaaaaagtcaaccgggaggaaatggaaagaaga
gtgaagactgaaactgaggagtactctgagaggttttcagagaatgccaagtccatctgc
agcatgttacttaccaaggatccaagtaaaaggctgggctgccagagtgatggagcctct
gctgtaaagcagcacccaatattcaaggatattaacttcagcagactggaagcaaatatg
ttagacccacctttctgtcctgatcctgaggccatttattgtaaggatatcttggatatt
ggacagttctctgtggtgaaaggagtcaacctggacaccaatgatgagatcttctacact
caatttgcgacagggtgtgtcaccattccctggcagaatgagatgattgaatctggatgt
ttcaaggacctcaatgaatatgaagataaaggtctgtcaccacttgaaaaacacaagata
tgttcctgtattcttagaccaaagagaaacttcttccatagactcttcagaagagcggcc
tgcctgaacattgcccacagtgaggagagggagccaacagaacactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (33)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (30)   
DNA sequence (40)   
   RefSeq(nuc) (38)   
   GenBank (1)   
   EMBL (1)   
Protein domain (5)   
   Pfam (5)   
All databases (92)   

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