KEGG   Rattus norvegicus (rat): 59113
Entry
59113             CDS       T01003                                 
Symbol
Kmo
Name
(RefSeq) kynurenine 3-monooxygenase
  KO
K00486  kynurenine 3-monooxygenase [EC:1.14.13.9]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00380  Tryptophan metabolism
rno01100  Metabolic pathways
rno01240  Biosynthesis of cofactors
Module
rno_M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
rno_M00912  NAD biosynthesis, tryptophan => quinolinate => NAD
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    59113 (Kmo)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.9  kynurenine 3-monooxygenase
     59113 (Kmo)
SSDB
Motif
Pfam: FAD_binding_3 NAD_binding_8 DAO SE Pyr_redox Pyr_redox_2 NAD_binding_7 3HCDH_N MurD-like_N FAD_binding_2 HI0933_like AlaDh_PNT_C
Other DBs
NCBI-GeneID: 59113
NCBI-ProteinID: NP_067604
RGD: 620610
Ensembl: ENSRNOG00000003709
UniProt: O88867 A6JGB4
Structure
Position
13:90089340..90121108
AA seq 478 aa
MASSDTEGKRVVVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVANFMRGRSINLALSY
RGRQALKAVGLEDQIVSKGVPMKARMIHSLSGKKSAIPYGNKSQYILSISREKLNKDLLT
AVESYPNAKVHFGHKLSKCCPEEGILTMLGPNKVPRDITCDLIVGCDGAYSTVRAHLMKK
PRFDYSQQYIPHGYMELTIPPKNGEYAMEPNCLHIWPRNAFMMIALPNMDKSFTCTLFMS
FEEFEKLPTHSDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKSRCV
LMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNDLSVCLPEFSRFRIPDDHAISDLS
MYNYIEMRAHVNSRWFLFQRLLDKFLHALMPSTFIPLYTMVAFTRIRYHEAVLRWHWQKK
VINRGLFVLGSLVAIGSAYILVHHLSPRPLELLRSAWTGTSGHWNRSADISPRVPWSH
NT seq 1437 nt   +upstreamnt  +downstreamnt
atggcatcgtcggacactgaaggaaaaagagtggttgttatcggtggtggtttggttgga
gcattgaacgcgtgctttctcgcaaagaggaatttccaagttgatgtgtacgaagctagg
gaagatattcgagtggctaactttatgcgtggaagaagcattaatttggccctttcttat
agaggacggcaggccttgaaggccgttggtctggaagatcagatcgtgtccaaaggtgtg
cccatgaaagccagaatgatccactctctctcgggaaagaagtctgcaattccctatggg
aacaagtcacagtatatcctttcaataagcagagaaaagttaaacaaggatctgctgact
gccgtggagtcctaccccaatgcaaaggtgcactttggccacaagctgtcaaaatgctgt
ccggaggaagggatactcacgatgcttggacccaacaaagttcccagagacatcacgtgt
gacctcattgtaggatgtgatggggcctactcaactgtcagagctcacctcatgaagaag
ccccgttttgattacagtcagcaatatatccctcatggctatatggagctgacaattcca
cctaagaacggggagtatgccatggaacctaactgtcttcacatttggcctagaaatgcc
tttatgatgatcgccctaccgaacatggacaaatctttcacatgcaccttgttcatgtcc
tttgaggagtttgaaaagcttccaacgcatagtgatgtgctggacttcttccagaagaac
tttccagatgccatccctctgatgggcgagcaagccctcatgagagatttctttctgttg
cctgcccagcccatgatatcagtaaagtgctctcccttccacctgaagtcacgctgtgtg
ctgatgggagatgcagctcatgccatcgtcccattttttgggcaaggaatgaatgcgggc
tttgaagactgcttggtatttgatgagttaatggacaaattcaataatgatcttagtgtg
tgccttcctgaattctcaagatttaggattcctgatgaccatgcaatttcagacctgtct
atgtacaattacatagagatgcgagcgcatgtcaactctaggtggttcctgtttcaaagg
ctcctggataaatttcttcatgcactaatgccatccactttcatccctctctataccatg
gtcgccttcaccagaataagataccacgaggcagtgctgcgctggcattggcaaaaaaag
gtgataaacagaggactctttgtccttgggtccctggtagccattggaagtgcctacata
ctcgtgcaccacctgtccccgagacctctggaactcctgagatctgcctggacgggaacc
tctggccactggaataggagtgcagacatttctccacgagttccatggagtcactag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (11)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (15)   
   RefSeq(nuc) (9)   
   GenBank (3)   
   EMBL (3)   
3D Structure (2)   
   PDB (2)   
Protein domain (12)   
   Pfam (12)   
All databases (63)   

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