KEGG   Rattus norvegicus (rat): 63836
Entry
63836             CDS       T01003                                 
Symbol
Actn4
Name
(RefSeq) alpha-actinin-4
  KO
K05699  actinin alpha 1/4
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04510  Focal adhesion
rno04520  Adherens junction
rno04530  Tight junction
rno04670  Leukocyte transendothelial migration
rno04810  Regulation of actin cytoskeleton
rno05146  Amoebiasis
rno05203  Viral carcinogenesis
rno05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    63836 (Actn4)
   04520 Adherens junction
    63836 (Actn4)
   04530 Tight junction
    63836 (Actn4)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    63836 (Actn4)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    63836 (Actn4)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    63836 (Actn4)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    63836 (Actn4)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    63836 (Actn4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    63836 (Actn4)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:rno04812]
    63836 (Actn4)
   04147 Exosome [BR:rno04147]
    63836 (Actn4)
Membrane trafficking [BR:rno04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    63836 (Actn4)
Cytoskeleton proteins [BR:rno04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     63836 (Actn4)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   63836 (Actn4)
  Exosomal proteins of colorectal cancer cells
   63836 (Actn4)
  Exosomal proteins of bladder cancer cells
   63836 (Actn4)
SSDB
Motif
Pfam: Spectrin CH EFhand_Ca_insen EF-hand_1 EF-hand_6 EF-hand_7 EF-hand_8 XisI
Other DBs
NCBI-GeneID: 63836
NCBI-ProteinID: NP_113863
RGD: 61816
Ensembl: ENSRNOG00000020433
UniProt: Q9QXQ0 A6J9M1
Position
1:complement(93310294..93379369)
AA seq 911 aa
MVDYHAANQAYQYGPSSGGNGTGGGGGMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWC
NSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIA
SKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPY
KNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKM
LDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYER
LASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTL
QTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQ
KASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQEL
NELDYYDSHNVNTRCQKICDQWDNLGSLTHSRREALEKTEKQLETIDQLHLEYAKRAAPF
NNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAES
NHIKLSGSNPYTSVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANM
VGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIF
DNKHTNYTMEHLRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKD
HGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETT
DTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAAPGALDYKS
FSTALYGESDL
NT seq 2736 nt   +upstreamnt  +downstreamnt
atggtggactatcacgcggcgaaccaggcgtaccagtacggcccaagcagcggcggcaat
ggcacgggcggcggcggaggcatgggcgactacatggcccaggaggatgactgggaccgg
gacctgctgttggacccggcctgggagaagcagcagcgcaagaccttcacagcctggtgc
aactcccatctgcggaaggctggcactcagatcgagaacatcgatgaggatttccgggat
gggctcaaacttatgcttctgctggaggtcatttcaggggagcggttgcctaagccagag
cgggggaagatgcgagtgcacaagatcaacaatgtaaacaaagccctggacttcatcgcc
agcaagggagtcaagctggtgtccattggggcagaagagatcgtggatggcaatgcaaag
atgaccctgggaatgatctggaccatcatcctcaggttcgccatccaagacatctctgtg
gaagagacctctgccaaggaaggactcctcctctggtgccagagaaagacagccccgtat
aaaaacgtcaacgtccagaacttccatatcagctggaaggatggtctggccttcaacgcg
ctcatccaccggcacagacctgagctgattgagtatgacaaactgaggaaggatgatcca
gtcaccaacctaaacaatgcatttgaagtggctgagaaataccttgatatccccaagatg
ttggatgctgaggacatcgtgaacacagcccggcccgacgagaaggccataatgacatat
gtgtccagcttctaccatgccttttcaggagcgcagaaggctgagactgctgccaaccgg
atctgcaaggtgctggctgtgaaccaggaaaatgagcacctgatggaagattacgagcgc
ctggccagtgatcttctagagtggatccggcgcaccatcccctggctggaagaccgtgtg
cctcagaagaccatccaggagatgcagcagaagctggaggacttccgagactataggcgt
gtgcacaagccccccaaggtacaggagaagtgtcagctggagatcaacttcaacaccctg
cagaccaagctgcggctgagcaaccggcctgccttcatgccctccgagggcaggatggtc
tcggacatcaacaatgggtggcaacatctggagcaggctgagaagggctatgaagaatgg
ctcttgaatgaaatccgtaggctggaacgacttgatcacctggcagagaaattccggcag
aaggcttccatccatgaggcctggaccgatgggaaggaggccatgctgaagcaccgggac
tatgagacagccaccctgtcagacatcaaagctctgatccgaaagcatgaggcctttgag
agtgacctggcggcgcaccaggaccgcgtggagcagatcgcggctattgcccaggagctc
aacgaactggactactatgactcccacaacgtcaacacacggtgccagaagatctgtgac
cagtgggataacctgggctctctgacccacagtcgcagggaagccttggagaaaacagag
aaacagctggagaccatcgaccagctacacttggagtatgctaagcgggccgcgcccttc
aacaactggatggagagtgccatggaggacctgcaggacatgttcatcgtccacaccatc
gaggagattgagggcctgatctcagcccacgaccagttcaagtccaccctgccagatgcc
gacagggagcgtgaggccatcctggccatccacaaagaggcccaaaggatcgctgagagc
aatcacatcaagctgtcgggcagcaacccctacaccagcgttacaccccagatcatcaac
tccaaatgggagaaggtgcagcagctggtgccgaagcgggaccacgcactcctggaagag
cagagcaagcagcaatccaatgagcaccttcgccgacagtttgccagccaagccaatatg
gtggggccctggatccagaccaagatggaggagattgggcgcatctccatcgagatgaac
gggactctggaagaccagctgagtcacttgaagcagtacgagcgcagcattgtggactac
aagcccaacctggacttgctggagcagcagcaccagctcatccaggaggccctcatcttc
gacaacaagcacaccaactacacaatggagcacctccgtgtgggctgggagcagctgctc
accaccattgcccgcaccatcaacgaggtagagaatcagatcctcacccgagatgccaag
ggcatcagccaggagcaaatgcaggagttccgagcctccttcaaccactttgacaaggac
catggcggggcactggggcctgaggaattcaaggcctgcctcatcagcctgggctacgac
gtggagaatgaccggcagggtgatgctgagttcaaccggatcatgagtgtggtcgacccc
aaccatagtggcctcgtgaccttccaagccttcattgacttcatgtcaagggagaccaca
gacacagacaccgccgatcaggtcatcgcctccttcaaggtcctggccggggacaagaac
ttcatcactgctgaggaacttcggagagagctgccccctgaccaggctgagtactgcatc
gcccgcatggcgccctaccagggccctgatgctgctccaggcgcccttgactacaagtcc
ttctctacagccctctatggggagagcgacctgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (21)   
   RefSeq(nuc) (5)   
   GenBank (8)   
   EMBL (8)   
Protein domain (8)   
   Pfam (8)   
All databases (56)   

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