KEGG   Rattus norvegicus (rat): 63864
Entry
63864             CDS       T01003                                 
Symbol
Hsd17b10
Name
(RefSeq) 3-hydroxyacyl-CoA dehydrogenase type-2
  KO
K08683  3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00280  Valine, leucine and isoleucine degradation
rno01100  Metabolic pathways
rno05010  Alzheimer disease
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    63864 (Hsd17b10)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    63864 (Hsd17b10)
   05022 Pathways of neurodegeneration - multiple diseases
    63864 (Hsd17b10)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:rno03029]
    63864 (Hsd17b10)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    63864 (Hsd17b10)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.35  3-hydroxyacyl-CoA dehydrogenase
     63864 (Hsd17b10)
    1.1.1.178  3-hydroxy-2-methylbutyryl-CoA dehydrogenase
     63864 (Hsd17b10)
Mitochondrial biogenesis [BR:rno03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial transcription and translation factors
   Mitochondrial ribonuclease P
    63864 (Hsd17b10)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   63864 (Hsd17b10)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Epimerase LPD7
Other DBs
NCBI-GeneID: 63864
NCBI-ProteinID: NP_113870
RGD: 69231
Ensembl: ENSRNOG00000003049
UniProt: O70351 B0BMW2
Structure
Position
X:24568551..24571012
AA seq 261 aa
MAAACRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF
APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV
NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL
PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV
IENPFLNGEVIRLDGAIRMQP
NT seq 786 nt   +upstreamnt  +downstreamnt
atggctgcggcgtgtcggagcgtgaagggcctggtggcagtaataaccggaggagcctcg
ggccttggcctgtctacagccaaaagactggtgggacaaggagccacagctgtacttctg
gacgtccctaactcagagggtgagaccgaagccaagaagttaggaggaaactgcatattt
gccccagcaaatgtgacctctgagaaggaggtacaagcagctttgactctagcaaaagaa
aagtttggccgtatagatgtggctgtcaactgtgcaggcattgcagtggccattaagaca
taccacgaaaagaagaaccaggtccacaccttggaggacttccagcgggttatcaatgtg
aatctcataggcactttcaatgtgatccgcctggttgctggtgtgatgggccagaatgaa
ccagaccagggaggtcaacgtggagttatcattaacactgccagtgtggctgcttttgag
ggccaggttggacaagctgcatactctgcatccaaagggggcatagtgggcatgacactg
cccattgctcgagatctggctcctataggcatccgtgtggtaacaattgctccaggtctg
tttgccaccccactgcttaccactctgccagacaaagtgcgcaacttcttggccagccag
gtacccttccccagccgactaggtgaccccgcggaatatgctcatctggtacagatggta
atcgagaacccattcttgaatggagaggtcatccggctggatggggccattcgaatgcag
ccttaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (2)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (3)   
   PDB (3)   
Protein domain (5)   
   Pfam (5)   
All databases (56)   

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