KEGG   Rattus norvegicus (rat): 64012
Entry
64012             CDS       T01003                                 
Symbol
Rad50
Name
(RefSeq) DNA repair protein RAD50
  KO
K10866  DNA repair protein RAD50 [EC:3.6.-.-]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno03440  Homologous recombination
rno03450  Non-homologous end-joining
rno04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    64012 (Rad50)
   03450 Non-homologous end-joining
    64012 (Rad50)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    64012 (Rad50)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:rno03032]
    64012 (Rad50)
   03400 DNA repair and recombination proteins [BR:rno03400]
    64012 (Rad50)
DNA replication proteins [BR:rno03032]
 Eukaryotic type
  DNA Replication Termination Factors
   MRN complex
    64012 (Rad50)
DNA repair and recombination proteins [BR:rno03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    MRN(MRX) complex
     64012 (Rad50)
    BRCA1-C complex
     64012 (Rad50)
   NHEJ (non-homologous end-joining)
    MRX complex
     64012 (Rad50)
SSDB
Motif
Pfam: AAA_23 Rad50_zn_hook AAA_21 SbcC_Walker_B SMC_N AAA_15 Crescentin POTRA_3 AAA_29 DUF2703
Other DBs
NCBI-GeneID: 64012
NCBI-ProteinID: NP_071582
RGD: 621542
Ensembl: ENSRNOG00000033065
UniProt: Q9JIL8
Position
10:complement(38310147..38362100)
AA seq 1312 aa
MSRIEKMSILGVRSFGIEDKDKQIISFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG
TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGEMVLVQRSMLCSQKSKKTEFKTLEGVITR
IKHGEKVSLSSKCAEIDREMISCLGVSKSVLNNVIFCHQEDSNWPLSEGKALKQKFDEIF
SATRYIKALDTLRQVRQTQGQKVKECQTELKYLRQNKEKACEIRDQITSKEAQLASSREI
VKAYENELEPLKNRLKEIEHNLSKIMRLDNEIKALDSRKKQMEKDNSELEQKMEKVFQGT
DEQLNDLYHNHQRTVREKERRLVDCQRELEKLSKEARLLNQERAELLVEQGRLQLQADRH
QEHIRARDSLIQSLAAHLELDGFERGPFSERQIKNFHELVRERQEREAKTASQLLSDLTD
KEALKQRQMDEMRDKKSGLGRMIELKTEILTKKQTELRNVRNELQQLEGSSDRILELDQE
LTKAERELSKAEKNSSIETLKAEILNLQSEKADLDRNLRKLDQEMEQLNHHTTTRTQMEM
LTKDKTDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKE
LASAEQNKNHINNELKKKEEQLSSYEDKLFDVCGSQDFESDLDRLKEDIEKSSKQRAMLA
GATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELK
KKERRRDEMLGLVPMRQSIIDLKEKEIPELRNRLQSVNRDIQRLKNDIEEQETLLGTVMP
EEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGVDLDRTVQQVNQEKQEKQHKLD
TVSSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIATNLQRRQQMEEQTVELSTEVQS
LNREIKDAKEQINPLEIALEKLQQEKEELIHRKNTSNKMAQDKINDIKEKVKNIHGYMKD
IENYIQDGKDDYKKQKETELNEVVIQLNECDKHKEKINKEMGTMRQDIDTQKIQERWLQD
NLTLRKRREELKEVEEERKQHLKEMGQMQVLQMKNEHQKLEENIDTIKRNHSLALGRQKG
YEEEILHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDHAIMKFHSMKM
EEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGR
CSAGQKVLASLIIRLALAETFCLNCGILALDEPTTNLDRENIESLAHALVEIIKSRSQQR
NFQLLVITHDEDFVELLGRSEYVEKFYRVKKNIDQCSEIVKSSINSLGSYVH
NT seq 3939 nt   +upstreamnt  +downstreamnt
atgtcccggatcgaaaagatgagcattctgggcgtgcgaagttttgggatagaggataaa
gataagcaaattatctctttcttcagccccctcacaattttggttggacccaatggggcg
gggaagacgaccatcattgaatgtctaaagtatatttgtactggagatttccctcctgga
accaaaggaaatacatttgttcatgatcccaaggttgctcaagaaacagatgtgcgtgcc
caaattcgcctgcagtttcgtgatgtcaatggagagatggtacttgtgcagaggtccatg
ctttgcagtcagaaaagtaaaaaaaccgaatttaaaaccctggaaggagtcattactaga
ataaagcacggtgaaaaagtcagtctcagctccaaatgtgcagaaatcgaccgagaaatg
ataagttgtcttggggtttccaagtctgtgctaaacaatgttattttctgccaccaagaa
gactcaaattggcctctaagtgaaggaaaggctctgaagcagaaatttgatgagattttt
tcagcaacaaggtacattaaagccctagatacgcttcgacaggtacgacagacacaaggt
cagaaagtaaaagaatgtcaaacagaattgaaatatctgaggcaaaataaggagaaagct
tgtgagatccgagatcagatcactagtaaggaagcccagttagcatcttcacgggaaatt
gtcaaagcctatgagaatgagcttgagccattgaagaatcgcctgaaagagattgaacat
aacctctctaaaataatgagacttgacaatgaaattaaagccttggatagcagaaagaag
caaatggaaaaagataacagtgaattagaacagaagatggaaaaggtttttcaagggact
gatgagcagctaaatgacttgtatcacaatcaccagagaactgtaagggagaaagaaagg
cgcttggtagactgtcagcgtgaactggagaagctgagtaaagaagctcggctcctcaac
caggaaagagcagagctgcttgtggagcagggtcgtctacaactacaggcagatcgacat
caagagcatatccgagccagagactcactgattcagtctttggcagcacatcttgaattg
gatggttttgagcgtggaccattcagtgaaagacagattaaaaactttcatgaacttgtg
agagagagacaggagagagaagctaaaactgccagccagctcttgagcgaccttacagac
aaagaagcgctgaagcagagacagatggatgagatgagggacaagaagagcgggctgggg
aggatgattgagctgaagaccgagatcctgacgaagaagcagactgagctgaggaacgtg
aggaatgagctgcagcagctggagggctcctcggacaggattctggagctggaccaggag
ctcacaaaagcggaacgtgaactaagcaaggctgagaaaaatagcagcatagaaacccta
aaagcagaaatactaaacctccaaagtgagaaagcggacctggacaggaacctgcggaaa
ctggatcaggagatggagcagttaaaccatcatacaacaacccgcacacagatggagatg
cttaccaaagacaaaactgacaaagatgaacagatcagaaaaataaagtccaggcacagt
gatgaactaacttcactgttgggatattttcctaacaaaaaacagcttgaagactggctt
cattctaaatccaaagagattaatcagaccagggacagacttgccaaactgaacaaagaa
ctagcttcagccgaacaaaataaaaatcatataaataatgagctaaagaaaaaggaagag
cagctgtctagttatgaagataaactgtttgatgtttgtggtagccaagattttgaaagt
gacttagacagacttaaagaagatattgaaaaatcctcaaagcagcgagccatgctggct
ggagccacagcagtttactcccagttcatcactcagctgacagatgaaaaccagtcctgt
tgcccagtctgtcagagagtatttcagacggaagctgaattacaggaagtcatcagtgac
ttgcagtccaagctgaggcttgctccagataaactcaagtcaacagaatcagaactaaaa
aaaaaagaacggcgccgtgatgaaatgctggggcttgtgcccatgaggcaaagcataatt
gatttgaaggaaaaggaaataccagaattaagaaacagactgcagagtgtcaatagagac
atacagcgcctaaagaatgacatagaggagcaggagacactcttgggtacagtgatgccc
gaagaggaaagtgctaaagtgtgcctgacagacgtcacgatcatggagaggttccagatg
gagctaaaagacgttgaaaggaaaattgcacagcaggcagctaagctgcagggggtagac
ttggatcggactgtccagcaggttaaccaggaaaaacaagaaaaacaacacaaactggat
acagtttccagtaagattgaattgaaccgtaagcttatacaggaccagcaggaacaaatt
cagcacctgaaaagtaaaacaaatgagctgaaatcagagaaactgcagatagccaccaat
ttgcaacggcgtcagcaaatggaggagcagactgtggaattatccactgaagttcagtct
ttgaacagagaaataaaggatgctaaagagcaaataaaccctttggagatagcactggaa
aagttgcagcaggaaaaagaagaattgatccacagaaaaaatacaagtaacaaaatggct
caggataagatcaatgatatcaaagagaaagttaaaaatattcatggttacatgaaagac
atagagaattatattcaagatggaaaagatgactataagaagcaaaaagaaactgaactt
aatgaagttgtcattcaactaaatgaatgtgacaaacacaaagaaaagataaataaagaa
atgggaaccatgaggcaagatattgacacacagaagatacaggaaaggtggttacaggat
aaccttacactgagaaaaagaagagaggaactaaaagaagttgaagaggaacgaaagcaa
catttgaaggagatgggacagatgcaagttttacagatgaaaaatgagcaccagaagttg
gaagagaacatagacacgataaagagaaatcacagtttggcattggggcgacagaaaggc
tatgaagaagaaattcttcactttaagaaggagctccgagaacctcagtttcgggatgca
gaggagaagtacagagaaatgatgattgtcatgagaaccacagagctggtgaataaggac
ctggacatctactacaaaactcttgatcacgcaataatgaaatttcacagtatgaaaatg
gaagaaatcaacaaaattattcgtgatctttggcggagtacctatcgtgggcaagatatt
gaatacatagaaattcgatccgatgctgatgaaaatgtatcagcttctgataaaaggcga
aattacaactaccgagtggtgatgctgaagggggatacagccttggacatgcgcggacga
tgcagtgctggacagaaggtgctggcctctctcatcatccgcctggcactggccgaaacc
ttctgtctgaactgcggcatccttgccttggatgagcctacaacaaacctggaccgagaa
aacatcgagtctctggcacatgctttggttgagattataaaaagtcgctcgcagcagcgc
aacttccagcttctggtcatcactcacgatgaagattttgtggagctcctaggacgatct
gagtatgtggagaaattctacagagtgaagaagaacatcgaccagtgctcagagattgtc
aagagcagcatcaactctctgggctcttatgttcactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (10)   
   Pfam (10)   
All databases (31)   

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