KEGG   Rattus norvegicus (rat): 64206
Entry
64206             CDS       T01003                                 
Symbol
Tdo2
Name
(RefSeq) tryptophan 2,3-dioxygenase
  KO
K00453  tryptophan 2,3-dioxygenase [EC:1.13.11.11]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00380  Tryptophan metabolism
rno01100  Metabolic pathways
rno01240  Biosynthesis of cofactors
Module
rno_M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
rno_M00912  NAD biosynthesis, tryptophan => quinolinate => NAD
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    64206 (Tdo2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.11  tryptophan 2,3-dioxygenase
     64206 (Tdo2)
SSDB
Motif
Pfam: Trp_dioxygenase
Other DBs
NCBI-GeneID: 64206
NCBI-ProteinID: NP_071798
RGD: 68370
Ensembl: ENSRNOG00000011612
UniProt: P21643 A6J5T5
Position
2:complement(169567656..169585586)
AA seq 406 aa
MSGCPFSGNSVGYTLKNLSMEDNEEDGAQTGVNRASKGGLIYGDYLQLEKILNAQELQSE
IKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVMTRMHRVVV
IFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHY
RDNFEGDYNELLLKSEQEQTLLQLVEAWLERTPGLEPHGFNFWGKFEKNILKGLEEEFLK
IQAKKDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYRE
EPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGSKAGTGGSSGYYYLRSTVSDRYK
VFVDLFNLSSYLVPRHWIPKMNPIIHKFLYTAEYSDSSYFSSDESD
NT seq 1221 nt   +upstreamnt  +downstreamnt
atgagtgggtgcccattttcaggaaacagtgtaggatatactttgaaaaacttatctatg
gaagacaatgaagaagacggagctcaaactggtgtaaacagagccagcaaaggaggactt
atctatggggactacttgcagttggagaagattttgaatgcacaagaacttcaaagtgaa
atcaaagggaataaaatccacgacgagcacctctttattataactcaccaagcttatgaa
ctttggtttaaacaaattctctgggaacttgattctgttcgtgagatttttcaaaatggc
catgtcagggatgagaggaacatgctcaaggtgatgactcggatgcaccgtgtggtggtc
atcttcaagctcctggtacagcagttctcggttctggaaacaatgactgccttggacttc
aatgacttcagagagtacctgtctccagcatcaggcttccagagtcttcagttccggctg
ctagaaaataagataggtgttcttcagagcttgagagtcccttacaacaggaaacactat
cgtgataactttgaaggagactacaatgagctgctgctgaaatcggagcaggagcagacg
ctattgcagctggtggaggcatggctggaacgcacacctggcttagagccacatggattc
aatttctggggaaagtttgaaaaaaatatcttgaagggtctggaagaggagttcctaaag
attcaggcgaaaaaggactctgaagaaaaagaggaacagatggcagagttccggaagcag
aaagaggtgctgctctgcttgttcgatgagaagcgtcatgactaccttctgagtaaaggt
gaacgacgactgtcataccgtgcactccagggagcactgatgatatatttttacagggag
gagcctcgattccaggtccctttccagttgctgacctcacttatggacattgacacactc
atgaccaaatggagatataatcatgtgtgcatggtgcacaggatgctaggcagcaaggct
ggcactgggggatcctcaggctattattatctgcgctcaactgtgagcgacaggtacaag
gtgttcgtggatttatttaacctctcatcgtacctggttccccgacactggataccaaag
atgaatccgatcattcacaagttcctttacacagctgagtacagcgacagctcctacttc
agcagcgatgaatcagattga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (1)   
   Pfam (1)   
All databases (31)   

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