KEGG   Rattus norvegicus (rat): 64677
Entry
64677             CDS       T01003                                 
Symbol
Srd5a2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
  KO
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00140  Steroid hormone biosynthesis
rno01100  Metabolic pathways
rno05215  Prostate cancer
Module
rno_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    64677 (Srd5a2)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    64677 (Srd5a2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     64677 (Srd5a2)
SSDB
Motif
Pfam: Steroid_dh DUF1295 PEMT
Other DBs
NCBI-GeneID: 64677
NCBI-ProteinID: NP_073202
RGD: 621480
Ensembl: ENSRNOG00000027042
UniProt: P31214 A6H9Z5
Position
6:27178089..27217588
AA seq 254 aa
MQIVCHQVPVLAGSATLATMGTLILCLGKPASYGKHTESVSSGVPFLPARIAWFLQELPS
FVVSVGMLAWQPRSLFGPPGNVLLALFSAHYFHRTFIYSLLTRGRPFPAVLFLRATAFCI
GNGLLQAYYLVYCAEYPEEWYTDVRFSFGVFLFILGMGINIHSDYTLRQLRKPGEVIYRI
PRGGLFTYVSGANFLGEIIEWIGYALATWSVPAFAFAFFTLCFLGMQAFYHHRFYLKMFK
DYPKSRKALIPFIF
NT seq 765 nt   +upstreamnt  +downstreamnt
atgcagattgtctgccatcaggtcccggtgctggcaggtagcgccacattggccactatg
gggaccctgatcctgtgcttagggaaacctgccagttacgggaaacacacagagagtgtg
tcgtcgggagttcccttcctgccggcacgcattgcctggttcctgcaggagttgccttcc
tttgtggtgtcggtagggatgctcgcttggcagccgcgctccctcttcggaccgcccggg
aatgtcctgctggctctcttctctgcacattacttccacaggacatttatttactcgttg
ctcacaagagggaggcctttcccagcggtgctgtttttgagagccactgccttctgcata
gggaacggactccttcaagcctactacctggtttactgcgcagaataccctgaggagtgg
tacacagatgtgcggtttagctttggtgtcttcctgtttattctggggatgggaatcaac
atccacagtgactacaccctgcgccagctcaggaagcctggagaagtcatctataggatt
cctcgaggtggcttgtttacgtatgtctctggagccaatttcctgggcgagattattgaa
tggattggctacgccttggccacgtggtccgtcccagccttcgctttcgcctttttcaca
ctttgtttcctggggatgcaagccttttaccaccacaggttctaccttaagatgtttaag
gattaccccaaatctaggaaagctctcattccattcatcttttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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