KEGG   Rattus norvegicus (rat): 65030
Entry
65030             CDS       T01003                                 
Symbol
Ephx2
Name
(RefSeq) bifunctional epoxide hydrolase 2
  KO
K08726  soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00590  Arachidonic acid metabolism
rno01100  Metabolic pathways
rno04146  Peroxisome
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    65030 (Ephx2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    65030 (Ephx2)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    65030 (Ephx2)
   05208 Chemical carcinogenesis - reactive oxygen species
    65030 (Ephx2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    65030 (Ephx2)
   01002 Peptidases and inhibitors [BR:rno01002]
    65030 (Ephx2)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.76  lipid-phosphate phosphatase
     65030 (Ephx2)
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.10  soluble epoxide hydrolase
     65030 (Ephx2)
Protein phosphatases and associated proteins [BR:rno01009]
 HAD phosphatases
  Other HAD phosphatases
   65030 (Ephx2)
Peptidases and inhibitors [BR:rno01002]
 Serine peptidases
  Family S33
   65030 (Ephx2)
SSDB
Motif
Pfam: Abhydrolase_1 Hydrolase Abhydrolase_6 HAD_2 Hydrolase_4 Hydrolase_like
Other DBs
NCBI-GeneID: 65030
NCBI-ProteinID: NP_075225
RGD: 620732
Ensembl: ENSRNOG00000017286
UniProt: P80299
Position
15:complement(44465447..44503157)
AA seq 554 aa
MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITF
SQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTC
IVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEV
VFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPEAPLPVPCSPNDVSHGYV
TVKPGIRLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSP
PEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNTPL
MPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTVNK
ATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWSCKALG
RKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILIKW
LKTEIQNPSVTSKI
NT seq 1665 nt   +upstreamnt  +downstreamnt
atggcgctgcgtgtggccgcgttcgaccttgacggagtgctggccctcccctctatagcc
ggggttctgcgccacaccgaggaggccctggcgctgcccagagacttcctacttggcgct
ttccagatgaaattcccagagggacccactgagcaactcatgaaaggaaagatcacattt
tcccagtgggtaccactcatggatgaaagctgcaggaagtcctccaaagcctgtggagcc
agtctacctgagaatttctccataagtgaaatattcagccaagccatggcagcaagaagc
atcaaccgccccatgcttcaggcagctgctgctctcaaaaagaaaggattcacaacgtgc
attgtcaccaacaactggctggacgacagtgacaagagagacatcctggcccagatgatg
tgtgagctgagccaacactttgacttcctcatagagtcctgtcaggtcgggatgatcaag
cctgagcctcagatctacaagtttgtactggacaccctgaaggcaaaacccaatgaggtt
gttttcctagatgactttggaagtaatctgaagccagcccgtgacatggggatggttacc
atcctggtccgcgacacagcctcggctttgagagaactggagaaagtcacagggacacag
tttcctgaggcacctctgccagtcccgtgcagtccaaatgatgtcagccatgggtatgtg
acagtgaagccagggatccgtctgcactttgtggagatgggctctggccctgctatatgc
ctctgtcatgggtttcctgagagctggttttcttggaggtaccagatccctgctctggcc
caggcgggctttcgtgttctagctatagacatgaaaggctatggagactcatcttctcct
ccagaaatagaagaatatgctatggaattgctgtgtgaggagatggtgacattcctgaat
aaactgggaatccctcaagcagtgttcattggccatgactgggctggtgtgctggtgtgg
aatatggctctcttccaccctgagagagtgagggctgtggccagtttgaacactccatta
atgccaccaaatcctgaggtgtcccccatggaagttatcagatcgatcccagttttcaac
tatcagctgtactttcaagagccaggagtggctgaggctgaactggaaaagaacatgagt
cggactttcaaaagcttcttccgaaccagtgatgatatgggtctcctcactgtgaataaa
gccactgaaatggggggaatccttgtgggaactccagaagatcccaaggtcagcaaaatt
actactgaggaggaaatagagtattacatacagcagttcaagaagtctggcttcagaggc
cctctaaactggtatcgaaacacagaaagaaactggaagtggagctgtaaggcgttggga
aggaagatcttggtccctgccctgatggtcacagctgagaaggacattgtactccgtcct
gaaatgtccaagaacatggaaaactggatccctttcctgaaaaggggacacatcgaagac
tgtggtcactggacacagatagagaaaccggcagaggtgaaccagattctcatcaagtgg
ctgaagactgaaatccagaacccatcggtgacctccaagatttag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (7)   
   KEGG ENZYME (2)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
Protein domain (6)   
   Pfam (6)   
All databases (58)   

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