KEGG   Rattus norvegicus (rat): 66018
Entry
66018             CDS       T01003                                 
Symbol
Pdgfd
Name
(RefSeq) platelet-derived growth factor D precursor
  KO
K05450  platelet derived growth factor C/D
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno04010  MAPK signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04020  Calcium signaling pathway
rno04072  Phospholipase D signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04510  Focal adhesion
rno04540  Gap junction
rno04810  Regulation of actin cytoskeleton
rno05215  Prostate cancer
rno05218  Melanoma
rno05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    66018 (Pdgfd)
   04014 Ras signaling pathway
    66018 (Pdgfd)
   04015 Rap1 signaling pathway
    66018 (Pdgfd)
   04020 Calcium signaling pathway
    66018 (Pdgfd)
   04072 Phospholipase D signaling pathway
    66018 (Pdgfd)
   04151 PI3K-Akt signaling pathway
    66018 (Pdgfd)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    66018 (Pdgfd)
   04540 Gap junction
    66018 (Pdgfd)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    66018 (Pdgfd)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    66018 (Pdgfd)
  09162 Cancer: specific types
   05218 Melanoma
    66018 (Pdgfd)
   05215 Prostate cancer
    66018 (Pdgfd)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    66018 (Pdgfd)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:rno04052]
    66018 (Pdgfd)
Cytokines and neuropeptides [BR:rno04052]
 Cytokines
  Growth factors (RTK binding)
   66018 (Pdgfd)
SSDB
Motif
Pfam: CUB PDGF
Other DBs
NCBI-GeneID: 66018
NCBI-ProteinID: NP_076452
RGD: 621880
Ensembl: ENSRNOG00000029148
Vega: OTTRNOG00000001039
UniProt: Q9EQT1 A6JN21
Position
8:11773335..12007277
AA seq 370 aa
MHRLILVSILVCANFCCYRDTFATPQSASIKALRNANLRRDESNHLTDLYRRDENIRVTG
TGHVQSPRFPNSYPRNLLLTWRLHSQEKTRIQLAFDHQFGLEEAENDICRYDFVEVEDVS
ESSTVVRGRWCGHKEIPPRITSRTNQIKITFQSDDYFVAKPGFKIYYSFVEDFQPEAASE
INWESVTSSFSGVSYHSPSVMDSTLTADALDKAIAEFDTVEDLLKYFNPASWQDDLENLY
MDTPRYRGRSYHERKSKVDLDRLNDDVKRYSCTPRNHSVNLREELKLTNAVFFPRCLLVQ
RCGGNCGCGTLNWKSCTCSSGKTVKKYHEVLKFEPGHFKRRGKAKNMALVDIQLDHHERC
DCICSSRPPR
NT seq 1113 nt   +upstreamnt  +downstreamnt
atgcaccggctcatcttagtctccattcttgtgtgtgcgaacttttgctgctatcgggac
acttttgcgactccgcagagcgcatccatcaaagctttgcgcaatgccaacctcaggaga
gatgagagcaatcacctcacagacttgtaccggagagatgagaacattcgggtgacaggc
actggccacgtgcagagtcctcgcttccccaacagctacccgaggaacctgctcctgaca
tggcggctccattcccaggagaaaacacggatacagctggcctttgaccatcaatttgga
ctggaggaagcagaaaatgacatttgtaggtatgactttgtggaagttgaagatgtctca
gaaagcagcactgttgtcagaggaagatggtgtggccataaggagatccctccaaggata
acttcaagaacaaaccagattaaaatcacatttcagtctgatgactattttgtggcaaaa
cctggattcaagatttattattcatttgtggaagatttccaacctgaagcagcctcagag
atcaactgggaatcagtcacaagttctttctctggggtgtcctatcactctccatcagta
atggactccactctcactgccgatgccctggacaaagctattgcagaattcgatactgta
gaagatctgcttaagtacttcaatccagcgtcttggcaagatgatctggagaatttgtac
atggacacccctcgttatagaggcaggtcataccatgaacggaagtctaaagtggacctg
gacaggctcaatgatgatgtcaagcgttacagttgcactcccaggaatcactcggtgaat
ctcagggaggagttgaagctgaccaacgcagtcttcttcccacgatgcctccttgtgcag
cgctgtggtggcaactgtggttgcggaactctcaactggaagtcctgcacgtgcagctca
gggaagacagtgaagaagtatcatgaggtactgaagtttgagcctggacatttcaaaaga
aggggcaaagctaagaatatggctcttgtcgatatccagttggatcatcatgagcgatgt
gactgcatctgcagctcaagaccacctcgataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (13)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (34)   

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