KEGG   Rattus norvegicus (rat): 679845
Entry
679845            CDS       T01003                                 
Symbol
Shc4
Name
(RefSeq) SHC-transforming protein 4
  KO
K17449  SHC-transforming protein 4
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno01522  Endocrine resistance
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04062  Chemokine signaling pathway
rno04072  Phospholipase D signaling pathway
rno04510  Focal adhesion
rno04650  Natural killer cell mediated cytotoxicity
rno04722  Neurotrophin signaling pathway
rno04910  Insulin signaling pathway
rno04915  Estrogen signaling pathway
rno04917  Prolactin signaling pathway
rno04926  Relaxin signaling pathway
rno04935  Growth hormone synthesis, secretion and action
rno05034  Alcoholism
rno05100  Bacterial invasion of epithelial cells
rno05206  MicroRNAs in cancer
rno05214  Glioma
rno05220  Chronic myeloid leukemia
rno05224  Breast cancer
rno05225  Hepatocellular carcinoma
rno05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    679845 (Shc4)
   04014 Ras signaling pathway
    679845 (Shc4)
   04072 Phospholipase D signaling pathway
    679845 (Shc4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    679845 (Shc4)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    679845 (Shc4)
   04062 Chemokine signaling pathway
    679845 (Shc4)
  09152 Endocrine system
   04910 Insulin signaling pathway
    679845 (Shc4)
   04915 Estrogen signaling pathway
    679845 (Shc4)
   04917 Prolactin signaling pathway
    679845 (Shc4)
   04926 Relaxin signaling pathway
    679845 (Shc4)
   04935 Growth hormone synthesis, secretion and action
    679845 (Shc4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    679845 (Shc4)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    679845 (Shc4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    679845 (Shc4)
   05226 Gastric cancer
    679845 (Shc4)
   05214 Glioma
    679845 (Shc4)
   05220 Chronic myeloid leukemia
    679845 (Shc4)
   05224 Breast cancer
    679845 (Shc4)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    679845 (Shc4)
  09165 Substance dependence
   05034 Alcoholism
    679845 (Shc4)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    679845 (Shc4)
   01522 Endocrine resistance
    679845 (Shc4)
SSDB
Motif
Pfam: PID SH2 Delta_lysin
Other DBs
NCBI-GeneID: 679845
NCBI-ProteinID: NP_001177994
RGD: 1583644
Ensembl: ENSRNOG00000037134
UniProt: D4A3K2
Position
3:complement(133334026..133428404)
AA seq 622 aa
MRERSQDSQAGLTLYVGLFGHLGMLHRTKYSRFRNESITSLDEGSPGGSVGNKGSSPPPY
AALTPHLPAEDATVPNQESPTALCTLIPRMASMKLANPVTFLSLKTFCLGSKQVPRLKLQ
ENQDQTPSSPASPETSLNSTGPAPTPLPDQVGCRPTSLRPDTCPLPGPGEPNPRSKQDGP
PLQHLLGNGLNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGVHGAIKKRK
APVKFLTTVLGKSNLQFSGMNIKLTVSTSSLTLMNLDNQQIIANHQMQSISFASGGDPDT
TDYVAYVAKDPVNQRACHILECRSGTAQDIISTIGQAFELRFKQYLKNPSLNTWEREEVL
VDGTSEDRGHDYYNSIPGKQPPAGGIADVRIQVQADPVAYCPIRCEKLCYLPGTSTCSGV
YKNCMGRSRPIGIPHERAMQSDAASLRHFWRVDLFDDPCYVNTQNMRGCAGNQSSTLPQG
SPWHLGKAPETVQPGATAKPGSSHALPHIKQQLWSEECFHGRLSRGAAERLLVKDGDFLV
RESVTSPGQFVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNSLPIISSG
SEVSLKQPVKKHNNPGLSHSKK
NT seq 1869 nt   +upstreamnt  +downstreamnt
atgcgagaacgcagccaggacagccaggcaggactcacgctgtatgtaggactctttggg
cacctggggatgcttcacaggaccaagtacagccgctttcggaacgagtccatcacgtct
ttggacgaagggagccccggaggctcggttggaaacaagggctcatcgccacctccttac
gcagccctgacccctcacctgcctgctgaagatgccactgtgcccaaccaggagagcccc
accgcgctgtgcaccttgattccccgtatggcaagcatgaagctggccaaccccgtcact
tttctgagtctgaaaaccttctgcctgggttcgaaacaggtgcccaggctgaagctccaa
gagaaccaggatcagactccaagcagcccagcgtccccagaaaccagtctgaatagtact
gggcctgcacctacacctcttccggaccaggtgggatgcaggcccacctccttgcgtcct
gatacttgcccactgcctgggcctggagaaccaaaccctaggagcaagcaggatggacct
cctctgcagcacctgttggggaacggtctcaactactgtgtgaggtacatgggctgcatt
gaagtgctgcagtcaatgaggtcactggattttggaatgagaacccaagttacaagggaa
gcaataagtcgcctgtgtgaagctgtccctggggtccatggagccattaaaaaacgaaag
gctcccgttaagttcctgacaacggttcttggcaaaagcaatcttcagttttcaggaatg
aatataaaactgactgtttcaacaagcagcctcacgctgatgaaccttgacaaccaacag
attattgcaaatcatcaaatgcaatcgatttcctttgcctctggaggggatcctgatacc
acagactatgttgcctatgtagctaaagatccagtcaaccaacgagcgtgccacatcctg
gagtgtcgcagtggaacggcccaagatatcataagcaccatagggcaggcctttgagctc
cggttcaaacagtacttgaagaatccttccttgaacacttgggaaagggaggaggtcctt
gttgatggcacctctgaagacagaggccacgactattacaactccatcccagggaagcag
ccccctgcaggcggcattgcagatgtgcggatccaggttcaagcagatccagtggcttac
tgccctatccggtgtgagaagttgtgctatttgcccgggacctccacgtgcagcggcgtg
tacaagaactgcatgggacggagcaggccaatcggtattccccacgagagagcgatgcag
agtgacgctgcatcgctgaggcacttctggcgagtggatctctttgatgacccctgctat
gtcaatacacagaatatgcgcggctgtgctggaaatcaaagctcaactctgccacaaggg
agcccatggcaccttggaaaggcaccagagaccgtgcagccaggagccaccgccaagcct
gggagctcacacgctttgccacacattaagcagcaactgtggagtgaggaatgcttccac
ggcaggctgagcaggggggcagcggagagacttttggtgaaggatggggactttttggtt
cgagagagtgtgacatctcctggccagtttgtactgagcggactgcaaggcggccaggcc
aagcatcttctcttggtggatcctgaaggcaaggtgaggaccaaggaccatgtgtttgat
aatgttggccacctgatcaaataccacatggataatagtttgccaatcatctcttctgga
agtgaagtaagccttaaacaaccagtaaaaaaacataataacccaggactttcgcactcg
aagaaatga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (22)   
   KEGG PATHWAY (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (3)   
   Pfam (3)   
All databases (40)   

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