KEGG   Rattus norvegicus (rat): 680537
Entry
680537            CDS       T01003                                 
Symbol
Nsd2
Name
(RefSeq) histone-lysine N-methyltransferase NSD2
  KO
K11424  [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00310  Lysine degradation
rno01100  Metabolic pathways
rno05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    680537 (Nsd2)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    680537 (Nsd2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:rno03036]
    680537 (Nsd2)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.357  [histone H3]-lysine36 N-dimethyltransferase
     680537 (Nsd2)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     680537 (Nsd2)
SSDB
Motif
Pfam: PWWP SET AWS C5HCH HMG_box PHD HMG_box_2 zf-HC5HC2H zf-HC5HC2H_2 MUM1-like_PWWP
Other DBs
NCBI-GeneID: 680537
NCBI-ProteinID: NP_001178481
RGD: 1307955
Ensembl: ENSRNOG00000038140
Position
14:complement(81057727..81135866)
AA seq 1365 aa
MEFSIRKSPLSVQKVVKCMKMKQAPEILGSANGKTQNCEVNHECSVFLSKAQLSNSLQEG
VMQKFNGHDALPFLPAEKLKDLTSCVFNGEPGAHDTKLCFETQEVKGIGTPPNTTPIKNG
SPEIKLKITKTYMNGKPLFESSICGDGAADMSQSEENGQKSDNKTRRNRKRSIKYDSLLE
QGLVEAALVSKISSPEDKKIPVKKESCPNSGRDRDLLLKYNVGDLVWSKVSGYPWWPCMV
SADPLLHNHTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEEQFEKLCQESAKQ
APTKAEKIKLLKPISGRLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLRLNPQVA
KEAGIATEPLGEMVDSSVANEEAAVDPGTMREEDIPVKRRRRAKRSSSAENQEGDPGTEK
STPPKMADAEPKRGVGSPAGRKRSTGSASRSRKGDSAAQFLVFCQKHRDEVVAEHPDASE
EEIEELLGSQWSMLNEKQKARYNTKFSLMISAQSEEDSGNTSGKKRTHTKRTDDPPEDVD
VEDAPRKRLRTDKHSLRKRETITDKTARTSSYKAIEAASSLKSQAATKNLSDACKPLKKR
NRASATASSALGFNKSSSPSASLTENEVSDNPGDEPSESPYESADETQTEASVSSKKSER
GMAAKKEYVCQLCEKTGSLLLCEGPCCGAFHLACLGLSQRPEGRFTCTECASGIHSCFVC
KESKMEVKRCMVNQCGKFYHEACVKKYPLTVFESRGFRCPLHSCMSCHASNPSNPRPSKG
KMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGHFTARKGKRHHTHVNVSWCFVCSKG
GSLLCCEACPAAFHPDCLSIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
ALQEAEARFNEIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
TDENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAK
RDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
FLGDRPKTSTSLSSEEKSKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFRSTQDGQ
SYCCEHDLRADSANNTKTEKPFLDSLKAKGKRKKRRCWRRVTDGK
NT seq 4098 nt   +upstreamnt  +downstreamnt
atggaatttagcatcagaaaaagtcctctttctgttcagaaagttgtaaagtgcatgaag
atgaagcaggcaccagaaatccttggcagtgcaaatggaaagactcagaactgtgaagtg
aatcacgaatgttctgtattcctcagcaaagctcagctttctaacagcctacaggagggg
gtcatgcagaaatttaacgggcatgatgcactcccctttcttccagcagagaagttgaaa
gatcttacttcttgtgtgtttaatggagaacctggtgctcatgatactaagttgtgtttt
gagacccaggaagtaaaaggaattgggacaccacccaatactactcctatcaaaaatggc
tctccagaaattaaactgaaaatcaccaaaacatacatgaatgggaaacctctctttgaa
tcttcaatttgtggtgatggcgctgctgatatgtctcagtcagaagaaaatggacaaaaa
tcggataataagactaggaggaacaggaagaggagcataaaatatgactctttgctggag
cagggccttgtggaagcagctttagtgtccaagatctcaagtcctgaagataaaaagatt
ccagttaagaaggagtcctgtccaaatagtggcagagacagagacctcttgttaaaatac
aacgttggtgatttggtgtggtccaaagtgtcaggttacccttggtggccttgcatggtt
tctgctgatccactccttcacaatcataccaaacttaaaggtcagaaaaaaagtgcacgc
cagtatcatgtacaattctttggtgatgccccagaaagagcttggatatttgagaagagc
cttgttgcttttgaaggagaagaacaatttgaaaaattatgccaagaaagtgccaagcag
gcacccacgaaagctgagaaaatcaagttgttgaaacctatttcagggagattgagagcc
cagtgggaaatgggcattgtccaggctgaggaagctgctagcatgtcagtagaggagcgg
aaagccaagtttactttcctttatgtgggggaccaactgcgcctcaaccctcaagtggct
aaggaggctggcattgctacagaacctttgggagaaatggtggactcttcagtggccaat
gaagaagctgctgtagaccctgggactatgagagaagaggacattcccgtaaagagaagg
cgaagagccaaaaggtctagttctgctgagaaccaggaaggagaccccggcacagaaaag
agtacacctccaaagatggcggatgctgaacctaagagaggcgtaggttctcctgccggg
aggaaaaggtccacaggatctgcctcacggagcagaaagggagactcagcagcccagttc
ttagtcttttgtcaaaaacacagggatgaggtcgtagctgaacacccagatgcctcagag
gaggagattgaagaattgcttgggtcccaatggagcatgctcaatgaaaagcagaaagca
cgatataatacaaagttttccctaatgatctctgcccagtctgaagaagactctggaaat
accagtgggaaaaaaaggacccacacaaaaaggacagatgaccctcctgaggatgtggat
gtagaagacgcacccaggaaaagacttaggacagataagcacagtcttcggaagagagag
acaatcaccgacaaaacggccagaacgagctcgtacaaggctatagaggcagcctcctca
ctcaagagccaggcagcaacgaaaaatttgtctgatgcttgcaaaccactgaagaagcga
aatcgggcttctgcaacagcgtcttcagcacttgggtttaacaaaagttcatctccttct
gcatccttaactgagaatgaggtctcagacaacccaggagatgaaccgtcagagtctccg
tatgaaagtgcagatgaaacacagactgaagcgtccgtctcatctaagaaatctgaaaga
ggaatggctgccaaaaaggagtacgtgtgtcagctgtgtgagaagacaggcagtctctta
ctgtgtgaaggcccctgttgtggagcattccacttagcctgccttggactttcccagaga
ccagaaggaagattcacctgcactgaatgtgcctcagggattcactcatgcttcgtatgt
aaagaaagcaagatggaggtgaaacgctgtatggtaaaccaatgtggaaagttttaccat
gaagcctgtgtgaaaaaataccctctcactgtgtttgagagccgaggctttcgctgtcct
ctccacagctgtatgagctgccatgcctcaaacccttcaaatccgcggccatcaaaaggt
aaaatgatgcggtgcgtccgatgccctgtcgcctatcatggcggggatgcctgcctggca
gcgggatgttccgtgattgcttctaacagcataatctgcacaggccacttcactgcccgc
aaggggaagcggcaccacactcatgtcaatgtgagctggtgcttcgtgtgctccaaaggg
ggaagccttctgtgctgcgaggcctgtccggcagccttccaccctgattgtttgagcatc
gagatgcctgatggcagctggttctgcaatgactgccgagctgggaagaagctccacttt
caagacatcatttgggtcaaacttgggaactacagatggtggccagcagaagtttgccat
cccaaaaatgttcccccaaatattcagaaaatgaagcacgagattggagaattccctgtg
tttttcttcgggtctaaagattattactggacgcatcaggcacgagtgttcccatacatg
gagggggaccggggcagccgctaccagggggtcagagggattggaagagtcttcaagaac
gcattgcaagaagccgaagctcgttttaatgaaatcaaacttcagcgggaagcccgagaa
acacaggagagtgagagaaagcctccaccatacaagcatatcaaggtgaataaaccttat
ggtaaagtccagatctatacagctgacatttctgaaatcccaaaatgcaactgtaagccc
acggatgagaacccctgtggctctgattcagagtgtctaaacaggatgctaatgtttgag
tgccacccgcaggtgtgccctgcaggggaatattgccagaaccagtgtttcactaagcgc
cagtacccggagaccaagatcatcaagaccgatggcaaagggtggggcctggttgccaaa
agggacatcagaaagggagaatttgttaatgagtatgttggcgaactgattgatgaagag
gagtgtatggcaagaatcaaatatgcacatgagaatgacatcactcacttttacatgctc
accatagacaaggaccgcataattgatgctggccccaaagggaattactcgcggttcatg
aaccatagctgccagcccaactgtgagaccctgaagtggacagtgaatggggacacacgg
gttggcctgtttgctgtgtgcgacatccctgcaggtacagagctgactttcaactataac
ctcgattgtttgggcaatgaaaagacagtctgtcggtgtggagcctccaactgtagtggg
ttccttggagacagaccaaagacatcaacatccctttcttcagaggaaaagagtaaaaag
gccaagaagaaaaccaggaggcgcagagccaagggtgaaggaaagcggcagtcagaggac
gaatgcttccgctgtggtgatggcggacaactggtgctgtgtgaccgcaagttctgcacc
aaggcctaccacctatcctgcttgggcttgggcaagcggccctttgggaagtgggaatgt
ccttggcatcactgtgatgtgtgtggcaaaccttctacctcattttgccacctctgcccc
aactcattctgtaaggaacaccaagatgggactgctttccgctccacccaggatgggcaa
tcctactgctgtgagcatgacctgagggcagactctgcaaataataccaagactgagaaa
ccctttctagactcactcaaggcgaaggggaagaggaagaaaaggcggtgctggcgaagg
gtcacagacggcaaatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (20)   
   RefSeq(pep) (20)   
DNA sequence (20)   
   RefSeq(nuc) (20)   
Protein domain (10)   
   Pfam (10)   
All databases (73)   

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