KEGG   Rattus norvegicus (rat): 690516
Entry
690516            CDS       T01003                                 
Symbol
Smurf1
Name
(RefSeq) E3 ubiquitin-protein ligase SMURF1
  KO
K04678  E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04120  Ubiquitin mediated proteolysis
rno04137  Mitophagy - animal
rno04144  Endocytosis
rno04340  Hedgehog signaling pathway
rno04350  TGF-beta signaling pathway
rno04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    690516 (Smurf1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    690516 (Smurf1)
   04350 TGF-beta signaling pathway
    690516 (Smurf1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    690516 (Smurf1)
   04137 Mitophagy - animal
    690516 (Smurf1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    690516 (Smurf1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    690516 (Smurf1)
   04121 Ubiquitin system [BR:rno04121]
    690516 (Smurf1)
   03029 Mitochondrial biogenesis [BR:rno03029]
    690516 (Smurf1)
Enzymes [BR:rno01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     690516 (Smurf1)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    690516 (Smurf1)
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    690516 (Smurf1)
Ubiquitin system [BR:rno04121]
 Ubiquitin ligases (E3)
  HECT type E3
   690516 (Smurf1)
Mitochondrial biogenesis [BR:rno03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    690516 (Smurf1)
SSDB
Motif
Pfam: HECT WW C2
Other DBs
NCBI-GeneID: 690516
NCBI-ProteinID: NP_001103068
RGD: 1594738
Ensembl: ENSRNOG00000000999
Vega: OTTRNOG00000000697
UniProt: A6K1G6
Position
12:14748717..14840273
AA seq 728 aa
MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP
KWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCK
LNPSDTDAVRGQIVVSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPA
PYTDGTGAAAGGGNCRFVESPSQDQRLLVQRLRNPEVRGSLQTPQNRPHGHQSPELPEGY
EQRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVD
HNNRTTQFTDPRLHHIMNHQCQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKVLR
HELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVARE
WLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYI
NGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRIL
QHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQK
ELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTR
VPLQGFKALQGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVE
ETCGFAVE
NT seq 2187 nt   +upstreamnt  +downstreamnt
atgtcgaaccccgggacccgtaggaacggctccagcatcaagatccgtctgacagtattg
tgtgccaagaaccttgcaaagaaagacttcttcagactccccgacccctttgccaagatt
gttgtggacggctctgggcagtgccactcaaccgacactgtgaaaaacaccctggaccca
aagtggaaccagcactatgacctgtacgttgggaaaaccgactcgataaccatcagtgtg
tggaaccacaagaagatccacaagaagcagggggctggcttcctgggctgcgtgcggctg
ctctccaatgccatcagcagattgaaagataccggctaccagcgtttggatctatgcaaa
ctaaatccctcagatactgatgcagttcgtggccaaatagtggtcagtttacagacccga
gacagaataggtggtggagggtcggtggtggactgcaggggactgctggagaacgaagga
acggtatatgaagactcaggccctggaaggccgctcagctgcctcatggaggaacctgcc
ccgtatacagatggcaccggtgcagcggcaggaggtgggaactgcaggtttgtggagtct
ccaagccaagatcagagactcctggtacagcgactccgaaatcctgaggttcgaggatcc
ctacagacaccgcagaatcgaccacatggccaccagtcaccggagctgcctgaaggctac
gagcaaaggacaacagtgcagggacaagtttactttttgcacacgcagactggagtcagc
acatggcacgaccccaggatccccagagaccttaacagtgtgaactgcgatgaacttggg
ccactgcctccaggctgggaagtcagaagcacagtgtcgggaagaatctattttgtagat
cacaataataggacaacccagtttacagacccacggcttcaccacatcatgaatcaccag
tgccaactcaaggagcccagccagccgctgcagttgcccagtgagggctccgtggaggac
gaggagcttcctgcccagagatatgagagagatttagtccagaagcttaaagttctcaga
catgagctctctcttcagcagccccaagctggtcattgtcgcatagaagtttccagagaa
gaaatatttgaggagtcatatcgccagatcatgaagatgcgaccaaaagacctgaagaag
cgcctgatggtgaagttccgaggggaggaaggcttggactatggtggggtggctcgggag
tggctgtatttgttgtgccatgaaatgttgaatccgtattatggactcttccagtattcc
acggacaatatttacacactgcaaatcaacccagattcttctatcaaccctgaccatctg
tcttacttccactttgtgggtcgcatcatgggtctggctgtgttccatggacactacata
aacgggggcttcacagttcctttctacaagcagctcctgggaaaacccatccagctgtcg
gatctggagtcagtggacccagaacttcacaagagcttggtgtggattctagagaatgac
atcacgccagtgctggatcacaccttctgcgtggagcacaatgcttttgggcggatcctt
cagcatgaactgaaacccaatggcagaaatgtgcctgtcactgaggagaacaagaaggag
tatgtgcggttgtatgtgaactggaggtttatgagaggaatcgaagcccagttcctagcg
cttcagaaagggtttaacgaactcattccccaacacttactgaagccctttgaccagaag
gaactagagctgataataggcggcctggataagatagacctgaatgactggaagtccaac
actcggctgaagcactgtgtggcagacagcaacatcgtcaggtggttctggcaggcggtg
gagaccttcgatgaggagaggagagccaggctcctgcagtttgtgacaggatccacacga
gttcctctccaaggcttcaaggctctgcaaggcgcggcagggccccggctcttcaccatc
cacctgattgacgccaacaccgacaacctgcccaaggcccacacctgctttaatcggatt
gacatcccaccctatgagtcctatgagaagctctatgagaagctgctgacagcggtagag
gagacctgtggctttgccgtggagtga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

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