KEGG   Rattus norvegicus (rat): 78966
Entry
78966             CDS       T01003                                 
Symbol
Arhgef11
Name
(RefSeq) rho guanine nucleotide exchange factor 11
  KO
K12331  Rho guanine nucleotide exchange factor 11
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04270  Vascular smooth muscle contraction
rno04928  Parathyroid hormone synthesis, secretion and action
rno05163  Human cytomegalovirus infection
rno05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    78966 (Arhgef11)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    78966 (Arhgef11)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    78966 (Arhgef11)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    78966 (Arhgef11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    78966 (Arhgef11)
Membrane trafficking [BR:rno04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    78966 (Arhgef11)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PDZ PDZ_6 RGS PDZ_2 PH_13 PH
Other DBs
NCBI-GeneID: 78966
NCBI-ProteinID: NP_076472
RGD: 619705
Ensembl: ENSRNOG00000015026
UniProt: Q9ES67
Structure
Position
2:175372269..175493852
AA seq 1527 aa
MSIRLPHSIDRSASKKQSHLSSPIASWLSSLSSLGDSTPERTSPSHHRQPSDTSETTAGL
VQRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHL
EVVKLIKSGAYAALTLLGSSPPSVGVSGLQQNPSVAGVPRVNPIIPPPPPPPPLPPPQHI
TGPKPLQDPEVQKHATQILRNMLRQEEKELQDILPPCGETSQRTCEGRLSVDSQEADSGL
DSGTERFPSISESLMNRNSVLSDPGLDSPQTSPVILARVAQHHRRQGSDAALLPLNHQGI
DQSPKPLIIGPEEDYDPGYFNNESDIIFQDLEKLKSHPAYLVVFLRYIFSQADPGPLLFY
LCSEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKIPEMLQAEIDLRLRNNEDPRNVLCE
AQEAVMLEIQEQINDYRSKRTLGLGSLYGENDLLGLDGDPLRERQMAEKQLAALGDILSK
YEEDRSAPMDFAVNTFMSHAGIRLRESRSSCTAEKTQSAPDKDKWLPFFPKTKKQSSNSK
KEKDALEDKKRNPILRYIGKPKSSSQSIKPGNVRNIIQHFENSHQYDVPEPGTQRLSTGS
FPEDLLESDSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSA
SSSASSLSTRSLENPTPPFTPKMGRRSIESPNLGFCTDVILPHLLEDDLGQLSDLEPEPE
VQNWQHTVGKDVVANLTQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMRKENLMPR
EELARLFPNLPELIEIHNSWCEAMKKLREEGPIIRDISDLMLARFDGPAREELQQVAAQF
CSYQSVALELIRTKQRKESRFQLFMQEAESHPQCRRLQLRDLIVSEMQRLTKYPLLLENI
IKHTEGGTSEHEKLCRARDQCREILKFVNEAVKQTENRHRLEGYQKRLDATALERASNPL
AAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLQVLLLEDLVVLLQRQEERLLLKCHSKTA
VGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNIWME
LLEEAVQNATKHPGAAPIPIHPSPPGSQEPAYQGSTSSRVEINDSEVYHTEKEPKKLPEG
PGPEQRVQDKQLIAQGEPVQEEDEEELRTLPRAPPSLDGENRGIRTRDPVLLALTGPLLM
EGLADAALEDVENLRHLILWSLLPGHTVKTQAAGEPEDDLTPTPSVVSITSHPWDPGSPG
QAPTISDSTRLARPEGSQPEGEDVAVSSLAHLPPRTRSSGVWDSPELDRNPAAEAASTEP
AASYKVVRKVSLLPGGGVGAAKVAGSNAIPDSGQSESELSEVEGGAQATGNCFYVSMPAG
PLDSSTEPTGTPPSPSQCHSLPAWPTEPQPYRGVRGGQCSSLVRRDVDVIFHTIEQLTIK
LHRLKDMELAHRELLKSLGGESSGGTTPVGSFHTEAARWTDYSLSPPAKEALASDSQNGQ
EQGSCPEEGSDIALEDSATDTAVSPGP
NT seq 4584 nt   +upstreamnt  +downstreamnt
atgagcatacgattgccccatagtatagacagatcagccagtaaaaagcagtctcacctg
tccagccccattgcatcctggttaagtagcctgtcttctctgggagattctacacctgaa
cgcacatccccttctcaccaccgccagccctctgacacttctgagacaacagcaggtctt
gttcagcgctgtgtcatcatccaaaaggaccagcatggctttggcttcacagttagtgga
gatcgcattgtactggtgcagtccgtgcgccctggaggcgcagccatgaaagctggtgtg
aaagagggtgaccggatcatcaaagtaaacggcaccatggtgaccaatagctcacacctg
gaggtggtaaagcttatcaaatctggcgcctatgctgcgcttaccctcctaggctcttct
cctccctccgtcggcgtctctgggctccagcagaatccatctgtggcaggagtgcccaga
gttaaccccatcattcctccaccacctcccccgccacccttgccacctccacagcacatt
actggacccaaacctcttcaggatcctgaagtccaaaagcacgccactcaaatcctcagg
aatatgctaagacaggaggagaaagagttacaggacatacttccaccctgtggtgagacc
agtcagagaacatgtgagggccgcctctctgtggactcccaggaggcagacagtggcttg
gattctgggacagaacgctttccctccatcagtgagtcattgatgaatcggaactcagta
ttgtcagatcctggactagacagccctcaaacctcccctgtaatcctggccagggtggcc
cagcaccacaggcgacagggctcagatgcagcgttgctcccgctcaaccaccagggtata
gatcaaagcccaaagcctctgattattggcccagaggaagattatgacccaggttatttc
aacaatgagagtgacatcatcttccaagatcttgaaaaactgaagtcacatccagcttac
ttggtagtttttctacgttacatcttctctcaggcagaccctggccccctgcttttttat
ttgtgttcagaagtttatcaacagacaaatcccaaagattcccgaagtctggggaaagac
atctggaacattttcctagagaaaaatgcgcctctcagagtgaagatccctgagatgttg
caggctgaaattgacctacgcctgcggaacaatgaggaccctcgcaatgtgctctgtgaa
gctcaggaggcagtcatgctggaaatccaggagcagatcaacgactacagatccaagcgt
actctgggcctgggcagcctctatggtgaaaatgacctgctaggcctggatggggaccct
cttcgagaacgccaaatggctgagaagcagctggctgcccttggagatatcttgtccaaa
tatgaggaagatcggagtgcccccatggactttgctgttaatacctttatgagccacgct
gggatccgtcttcgggagtctcgatcctcctgcacggcagaaaagacccagtctgcccct
gacaaggacaagtggctgcccttcttccctaagaccaagaagcagagcagcaattccaag
aaagaaaaggatgccttggaggacaagaagcgaaaccccatcctcagatatattgggaag
cccaagagctcctctcagagcattaagccaggcaatgtgaggaacatcattcagcacttt
gagaacagccatcagtatgatgtcccagagccggggacacaacgactctcaacaggaagc
tttcctgaggacctgctggagagtgacagttcgcgctcagagattcgactgggccgctct
gagagcctcaagggccgggaagagatgaagcgatcccggaaagcagagaacgtgccccgg
tctcgaagtgacgttgacatggatgctgctgcagaggctgcccgccttcaccagtcagcc
tcgtcctctgcctccagcctctccaccaggtctcttgagaacccaacccctcccttcacc
cccaaaatgggccgcaggagcattgagtcccccaatctggggttctgtacagatgtcatc
cttccccacctcctggaggatgatctgggccaattgtctgacctggagccagagccagag
gtccaaaactggcagcatacagtaggcaaggatgtggtggccaacctgacccagagggaa
attgaccggcaagaggtcatcaatgagctttttgtgacagaagcatctcacctgcgcaca
ctccgagtcctggacctcatcttctaccagcgcatgagaaaggagaacctaatgcctcgg
gaagagctagcgcggctcttccctaacctgcctgagctcatagagattcacaattcctgg
tgtgaggccatgaagaagctccgggaggagggccccattatcagagacatcagtgacctc
atgctggctcggtttgatggtcctgcccgagaagaactccagcaagtagctgcacaattc
tgttcctatcagtcagtagccctagagctaatcaggactaagcaacgtaaggagagtcgg
ttccagctcttcatgcaggaggctgagagccaccctcagtgccggcgtctgcagctccga
gacctcatcgtctctgaaatgcaacggctcaccaagtacccactgctgctagagaacatc
atcaagcacacagagggtggcacctctgagcatgagaagctctgccgtgcccgggaccag
tgccgggagattctcaagtttgtgaatgaagcagtaaagcagacagagaaccgccaccgg
ctagaggggtaccagaaacgcctggatgccactgccctagagcgggccagcaaccccttg
gcagcagagttcaagagcctggatcttacaacaaggaagatgatccacgaggggcctctg
acctggaggatcagcaaagacaagaccctggacctccaggtgcttctgcttgaggacctg
gtggtactgctgcagagacaagaggagcggctgctgctaaagtgccacagcaagacagcc
gtgggctcctccgacagcaagcagacgttcagccctgtgctgaagctcaatgctgtgctc
atccgctccgtggctacagacaagcgagccttcttcatcatctgcacctccgagctgggc
cctccccagatctatgagctggttgcattgacgtcatcagacaagaatatatggatggag
ctcttagaagaggccgtgcagaatgccaccaagcaccctggagctgccccaatccccatc
catccctcaccaccaggatcccaggagccggcctaccagggctccacctccagcagggta
gaaataaatgactcagaagtatatcacactgaaaaagaacccaagaagctacctgaaggc
cccgggcctgagcagagagttcaagacaagcagctgatagcacaaggggagcctgtgcag
gaagaggatgaagaggaattgaggaccttgcctcgagctcccccctccctggatggagaa
aacagaggcatcaggacaagggaccctgtccttctggccctcacaggccctctgctcatg
gagggacttgctgatgctgccctggaagatgtggagaacttgcgtcacctgatcctgtgg
agcctgctgcctggtcacactgtgaagactcaggctgctggcgagcctgaggatgacctc
acacccaccccttctgtcgtgagcatcacctctcacccctgggacccagggtccccaggg
caagctcccaccataagtgacagcacccgacttgcgaggccagagggcagccagccagag
ggcgaggatgttgctgtcagttctctggcacacctgccgccaaggaccagaagttctggc
gtctgggactctcctgagctggataggaatccggctgcagaggctgcaagcacagaacca
gcagcaagttacaaggttgtgagaaaagtctctctactccctggtggtggtgtcggtgca
gccaaggtggcgggcagcaatgctatccctgacagtggccagtcagaatctgagctatct
gaagtggaaggcggagcacaggctacggggaactgtttctatgtcagcatgccagcagga
cctctggactccagcactgagcctactgggacacccccaagcccctcacagtgtcacagc
ctccctgcatggccaacagagcctcagccctacaggggagtccgtgggggtcagtgttcc
agcctggtccggagggatgtggatgtgatcttccataccatcgagcagctcaccatcaag
cttcacagactgaaggacatggagctggcccacagagagctgctcaagtcccttggagga
gagtcatcgggtggaaccacacctgtggggagttttcacacagaggcagccagatggaca
gactactccctctctcctccagccaaggaagccctggcctctgattcccaaaatggtcag
gagcaggggtcctgccctgaagaaggctccgacatcgccctggaagacagtgccactgac
acagctgtgtcaccaggaccatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (29)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (27)   
DNA sequence (29)   
   RefSeq(nuc) (27)   
   GenBank (1)   
   EMBL (1)   
3D Structure (3)   
   PDB (3)   
Protein domain (9)   
   Pfam (9)   
All databases (83)   

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