KEGG   Rattus norvegicus (rat): 79107
Entry
79107             CDS       T01003                                 
Symbol
Duox2
Name
(RefSeq) dual oxidase 2 precursor
  KO
K13411  dual oxidase [EC:1.6.3.1 1.11.1.-]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04918  Thyroid hormone synthesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    79107 (Duox2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    79107 (Duox2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.3  With oxygen as acceptor
    1.6.3.1  NAD(P)H oxidase (H2O2-forming)
     79107 (Duox2)
Membrane trafficking [BR:rno04131]
 Others
  NADPH oxidases (Nox) and associated proteins
   NADPH oxidases
    79107 (Duox2)
SSDB
Motif
Pfam: An_peroxidase NAD_binding_6 FAD_binding_8 EF-hand_1 Ferric_reduct EF-hand_7 EF-hand_6 EF-hand_8 EF-hand_5 NAD_binding_1 TMEM132D_C
Other DBs
NCBI-GeneID: 79107
NCBI-ProteinID: NP_077055
RGD: 628761
Ensembl: ENSRNOG00000017395
UniProt: Q9ES45
Position
3:complement(129680543..129698886)
AA seq 1517 aa
MLPTSLKTLVLLGALLTGPLGPAGGQDAPSLPWEVQRYDGWFNNLKYHQRGAAGSQLRRL
VPANYADGVYQALQEPLLPNARLLSDAVSKGKAGLPSAHNRTVLGLFFGYHVLSDLVSVE
TPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDRSTGQSPSNPRDLTNQVTGWLD
GSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQNSLLMWMAPDPATGQGGPQGLYAF
GAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNIALYQ
WLPSFLQKTPPEYSGYRPFMDPSISPEFVAASEQFLSTMVPPGVYMRNSSCHFREFPKEG
SSSSPALRVCNNYWIRENPSLKTAQDVDQLLLGMASQISELEDRIVIEDLRDYWPGPDRY
SRTDYVASSIQSGRDMGLPSYSQALQALGLEPPKNWSALNPKVDPQVLEATAALYNQDLS
RLELFLGGLLESHGDPGPLFSNIILDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTTL
RDVLVAVSNVDPSALQPNVFFWQEGAPCPQPQQLTTEGLPQCVPVTVIDYFEGSGAGYGV
TLLAVCCFPVVSLIIAWVVARFRNRERKMLLKKGKESLKKQTASDGVPAMEWPGPKESSY
PVTVQLLPDRSLKVLDKRLTVLRTIQLQPTQQVNLILSSSHGRRTLLLKIPKEYDLVLMF
NSEEDRDAFVQLLQDLCVCSTPGLRIAEMDEKELLRKAVTKQQRAGILEIFFRQLFAQVL
DINQADAGTLPLDSSQQVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYIS
FREFLDILVVFMKGSPQDKSRLMFTMYDLDGNGFLSKEEFFTMMRSFIEISNNCLSKDQL
AEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGGAGGTGDIFKQSNACR
VSFLTRTPGNRVMAPSPRLYTEALQEKMQRGFLAQKLKQFKRFVENYRRHIVCVTIFSAI
CAGLFADRAYYYGFASPPTDIEETTYVGIILSRGTAASISFMFSYILLTMCRNLITFLRE
TFLNRYIPFDAAVDFHRWIAMAAVVLAVVHSLGHAVNVYIFSVSPLSLMTCVFPSVFVND
GSKLPPKYYWWFFETVPGMTGVLLLLVLAIMYVFASHHFRRHSFRGFWLTHHLYVVLYAL
IIIHGSYALIQLPSFHIYFLVPAIIYVGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQR
PKTFEYKSGQWVRIACLSLGTNEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSPPV
GGTSARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSMGAQMLC
KKIYFIWVTRTQRQFEWLADIIREVEENDSRDLVSVHIYITQLAEKFDLRTTMLYICERH
FQKVLNRSLFTGLRSVTHFGRPPFELFLDSLQEVHPQVHKIGVFSCGPPGMTKNVEKACQ
LINRQDRAHFVHHYENF
NT seq 4554 nt   +upstreamnt  +downstreamnt
atgcttccaacaagtctcaagacattggtgctcctgggcgctctgttgactggacccctg
ggtccagcaggtggccaggatgcaccctcactgccctgggaagtgcagcgctacgacggc
tggtttaataatctcaagtaccaccagcgcggtgcagctggctcgcagctgcgtcgccta
gtacctgctaattacgctgacggtgtttatcaggctctgcaggagccgctactccccaac
gctcgcctgctaagcgacgctgtcagtaagggcaaagcagggctgccctcggcgcacaac
cgcacagtgcttgggctcttctttggctatcacgtgctctcagacctggtgagtgtggaa
acaccaggctgccccgcagagttcctcaacatttacatcccacgtggggacccagtgttt
gaccctgacaagcgcgggaacgtggtgctgccctttcagaggagccgctgggaccgcagc
actggacagagccctagcaacccccgagacctgaccaaccaggtgactggctggctagat
ggcagcgccatctatggctcctctcattcctggagcgacactctgaggagcttctctgga
ggacagctggcttctggccctgaccctgctttcccgaggaactcccagaactctctgctc
atgtggatggcaccagaccccgccacggggcagggcgggccacaggggctgtatgccttc
ggggcccagcgcgggaacagggagccctttctgcaggcactgggcttgttgtggtttcga
taccacaacctgtgtgccaagaggctggcgcaggagcacccacactggggggatgaggag
ctgttccagcatgctcgcaagagggtcattgccacttaccagaacattgctctataccaa
tggttgcccagcttcctgcagaaaacacccccagagtattccgggtaccgccctttcatg
gaccccagcatctccccagagttcgtggcggcctcagagcagttcctctctaccatggtg
cccccgggggtctatatgagaaactccagctgtcacttccgggaattcccaaaggaaggt
tccagcagctctccagctctcagggtctgcaacaactactggattcgggagaaccccagt
ctgaagactgctcaggacgtggaccagctgctgctgggaatggcttcccagatttcagag
ctggaggacaggatagtgattgaagatctgagagattactggcctggcccagacagatac
tctcgcacagactacgtggctagcagtatccagagtggccgagatatggggctgcccagt
tatagccaggctctgcaggccttaggactggagcctcccaagaattggagtgctctcaac
cccaaagtggatccccaggtgctggaggccacagctgctctgtacaaccaggacctgtcc
cggttggaactattcctgggagggctcctggagagccatggggaccctggacctctattc
agcaacatcattcttgaccagtttgtaaggctccgggatggtgatcgctactggtttgag
aacactaggaacgggctgttctccaaggaggagattgcagaaatcagaaacaccaccttg
cgggatgtactggtagctgtctccaatgtggaccccagtgccttgcagcccaatgttttc
ttctggcaagaaggtgcaccctgcccacagcctcagcaactcacaactgaaggcttgccc
cagtgtgtgcctgttactgtgattgactactttgagggcagtggtgctggctatggtgtc
accctcctggctgtctgctgctttccagtagtgagtctgattattgcttgggtggtggct
cgtttccggaaccgagaacgcaagatgctactaaagaaaggcaaggagagtctaaagaaa
cagacagccagtgatggagtaccagcgatggagtggccaggccccaaggagagcagctac
ccagtcactgtccagctgcttccagacaggagtctgaaggtccttgacaaaaggctcact
gtgctccgtaccatccaactgcagcccacacagcaggtcaacctcatcctgtccagcagc
catggacgccgcaccctgttgctcaagatccccaaggagtacgacctggtgctgatgttt
aactctgaagaggaccgggatgccttcgtgcagctgttgcaagacctctgcgtctgctcc
actcccggcctccgcatagctgagatggatgagaaggagctactgagaaaggctgtgacc
aagcagcagcgggcaggcatcttggagatcttcttcagacagctttttgctcaggtgctg
gacatcaatcaggccgacgcagggactctgcctctggactcatcccagcaagtacgagag
gctctgacctgtgaactgagcagagcggagtttgcggactccctgggcctcaagccccag
gatatgtttgtggagtccatgttttctctggccgacaaggatggcaatggctacatatcc
ttccgggagttcctggacatcctggtggttttcatgaaaggttccccacaggacaagtct
cgcctaatgtttaccatgtatgacctggatggaaatggctttctctccaaggaggaattc
ttcaccatgatgcggtccttcatcgagatctccaacaactgcctgtccaaggaccagctg
gctgaggtggtggaatccatgttccgggagtcgggcttccaggataaggaggagctgacc
tgggaggacttccatttcatgctgcgcgaccacgacagcgatctccgattcacacagctc
tgtgtcaaaggtggggctggaggcaccggggacatctttaagcaaagcaatgcctgtcga
gtctcattcctcacccggactcctgggaacagggtaatggctccctctccccggctgtac
acggaagcactgcaggagaaaatgcagaggggcttcctagcccagaagctcaagcagttc
aagcggtttgtggaaaactaccggcgccacatcgtgtgtgttacaatcttctcagccatc
tgcgcaggcctgtttgcagaccgtgcctactactatggctttgcctcgccacccacggac
attgaagaaaccacctatgtgggcatcatcctgtcccggggcacagcagccagcatctcc
ttcatgttctcctacatcctgctcaccatgtgccgcaacctcatcaccttcctgcgggag
accttcctcaaccgctacattccctttgatgctgctgtggacttccaccgctggatcgcc
atggctgcagttgtcctagctgttgtgcacagtcttggacatgcagtcaacgtgtacatc
ttctcagtcagtcccctcagcctgatgacctgcgtcttccctagtgtctttgtgaatgat
gggtccaagcttcccccaaagtactactggtggttcttcgagacagttccaggtatgaca
ggagtactcctgctcctggtcctggctatcatgtatgtgtttgcctcccaccacttccgc
cgccacagtttccggggcttctggttgacccaccacctctatgttgtgctttatgccctg
atcatcatccatggcagctatgccctcatccaattacccagcttccacatctacttcctg
gtccccgccattatctatgtgggggacaagctggtgagcctgagccggaagaaggtggag
atcagtgtggtgaaggctgagctgctgccttcaggggtgacctatctgcagttccagcgg
cccaagacttttgagtacaaatccgggcagtgggtgcggatcgcttgcttgagtctggga
accaatgagtaccaccccttcacgctgacctccgcaccccatgaggacacactcagcctg
cacatccgggctgtgggaccttggactactcgcctcagggagatctactcacctccagtg
ggtggcaccagcgccagatacccaaagctgtacctcgatggaccattcggagagggccac
caggaatggcacaagtttgaggtgtcggtgctggtaggagggggcattggggtcaccccc
tttgcctccatcctcaaagacctggtcttcaaatcgtccatgggtgcccagatgctatgt
aagaagatctacttcatctgggtgacaaggactcagcggcagtttgagtggctggctgac
atcatccgggaagtggaggagaatgacagccgggacctggtgtctgtgcacatctatatc
actcagctggctgagaagtttgacctcaggacgaccatgctgtacatctgtgagaggcac
ttccagaaggtgctgaacaggagtctgttcacgggcctgcgctctgtcacccactttggt
cgccctccctttgagctcttcttagactctctgcaggaggttcatccacaggtacataag
attggtgtgttcagctgtggtcctccagggatgaccaagaatgtggagaaggcctgtcag
ctcatcaacaggcaggaccgggcccactttgtgcatcattatgagaacttctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (8)   
   RefSeq(nuc) (4)   
   GenBank (2)   
   EMBL (2)   
Protein domain (11)   
   Pfam (11)   
All databases (37)   

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