KEGG   Rattus norvegicus (rat): 79243
Entry
79243             CDS       T01003                                 
Symbol
Hsd17b2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
  KO
K13368  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00140  Steroid hormone biosynthesis
rno01100  Metabolic pathways
rno04913  Ovarian steroidogenesis
Module
rno_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    79243 (Hsd17b2)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    79243 (Hsd17b2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     79243 (Hsd17b2)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     79243 (Hsd17b2)
SSDB
Motif
Pfam: adh_short adh_short_C2 DUF1776 KR Polysacc_synt_2 Epimerase NmrA
Other DBs
NCBI-GeneID: 79243
NCBI-ProteinID: NP_077367
RGD: 621803
Ensembl: ENSRNOG00000013982
UniProt: Q62730 F7EZ71
Position
19:62662320..62733944
AA seq 381 aa
MNPFSSESAWLCLTATAVLGGMLLCKAWSSGQLRSQVVCLAGLWGGACLLSLSLLCSLFL
LSVSCFFLLYVSSSDQDLLPVDQKAVLVTGADSGFGHALAKHLDKLGFTVFAGVLDKEGP
GAEELRKNCSERLSVLQMDVTKPEQIKDVHSEVAEKIQDKGLWAVVNNAGVLHFPIDGEL
IPMTVYRKCMAVNFFGAVEVTKVFLPLLRKSKGRLVNVSSMGAMIPFQMMAAYASTKAAI
SMFSAVIRQELAKWGVKVVTIHPGGFQTNIVGSQDSWDKMEKEILDHFSKEIQENYGQEY
VHTQKLALPVMREMSNPDITPVLRDIQHAICAKNHSSFYCSGRMTYLWICFAAYSPISLL
DYILKNYFTPKLMPRALRTAS
NT seq 1146 nt   +upstreamnt  +downstreamnt
atgaacccgttttcctctgagtcagcatggctctgcttgactgccactgcggtgctgggg
ggcatgcttctctgcaaagcctggagttcagggcagctaaggagccaggtggtgtgtctg
gctggcctctggggaggtgcctgcctgctcagcctgtccctcctctgcagcttgttcctc
ttatcggtgtcctgcttcttccttctgtatgtgagttcatctgaccaagacttgttacct
gtggatcaaaaggctgtgctggtgacaggtgccgattccggtttcggtcatgctttggcc
aagcacctggacaagctgggtttcacagtgtttgctggagtgctggataaagagggccca
ggagcggaggaattgaggaaaaactgctctgagcgcctttcggtgctccagatggatgtc
accaagccagagcagataaaagatgttcacagcgaagtcgcagagaagatacaagacaaa
ggactgtgggctgtggtcaacaatgctggggtcttgcactttccgatcgacggggaactc
attcccatgaccgtgtacagaaaatgcatggcagtgaacttcttcggagccgtcgaggtc
accaaggtgtttctgcctctacttagaaagtccaaggggaggctggttaacgtcagcagc
atgggagccatgattccatttcagatgatggccgcctacgcctccacgaaggcagctata
agcatgttctcagccgtcatcaggcaagagcttgccaaatggggagtcaaagtcgtgacc
atccatcctggaggcttccaaacaaacatcgtaggctcacaggacagttgggataaaatg
gagaaggagatcctggaccacttttccaaagagattcaggagaactatggacaggaatat
gtccatacgcagaagctcgccctcccggtcatgagagagatgtccaacccggatatcacc
cctgtgctgcgggacatccagcacgccatttgtgccaagaaccactcttccttttattgc
tcagggagaatgacttacctgtggatctgcttcgcggcctactccccgatcagcttattg
gactatattttgaaaaactattttactccaaaactcatgccaagagctttaaggacagca
agttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (7)   
   Pfam (7)   
All databases (51)   

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