KEGG   Rattus norvegicus (rat): 79244
Entry
79244             CDS       T01003                                 
Symbol
Hsd17b4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2
  KO
K12405  (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00120  Primary bile acid biosynthesis
rno01040  Biosynthesis of unsaturated fatty acids
rno01100  Metabolic pathways
rno01212  Fatty acid metabolism
rno04146  Peroxisome
Module
rno_M00861  beta-Oxidation, peroxisome, VLCFA
rno_M00862  beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    79244 (Hsd17b4)
   01040 Biosynthesis of unsaturated fatty acids
    79244 (Hsd17b4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    79244 (Hsd17b4)
Enzymes [BR:rno01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.107  3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
     79244 (Hsd17b4)
    4.2.1.119  enoyl-CoA hydratase 2
     79244 (Hsd17b4)
SSDB
Motif
Pfam: MaoC_dehydratas adh_short adh_short_C2 SCP2 KR Alkyl_sulf_C MaoC_dehydrat_N AbrB-like Epimerase
Other DBs
NCBI-GeneID: 79244
NCBI-ProteinID: NP_077368
RGD: 621806
Ensembl: ENSRNOG00000015840
UniProt: P97852 Q6IN39
Structure
Position
18:45515427..45604467
AA seq 735 aa
MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE
EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ
RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI
EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH
KIDSEGISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDL
KFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSG
ELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAA
VAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFSA
RHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNA
YVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVA
AKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIM
LSQKLQMILKDYAKL
NT seq 2208 nt   +upstreamnt  +downstreamnt
atggcttcgcctctgaggttcgacgggcgtgtggtcctggtcaccggcgccgggggaggg
ttgggcagagcttatgccctggcttttgcagaaagaggagcattagttgttgtgaatgac
ttaggaggggacttcaaaggcgttgggaaaggctcttctgccgcagacaaggtcgtggaa
gaaataagaaggagaggcgggaaagcggtggccaattacgattcagtcgaagcaggcgag
aagcttgtgaagacagcactggacacattcggcagaatagatgttgtggtgaacaatgct
gggatcctgagggaccgttccttctctaggataagtgatgaagactgggatataattcaa
agagttcatttgcggggctccttccaagtgacccgggcagcatgggatcatatgaagaag
cagaattatggaagaatcattatgacggcctcagcttctggaatatacggcaactttggc
caggcaaattatagtgctgcaaagctgggccttctgggtctcgccaatactctcgtgatt
gaaggcaggaagaacaacattcattgtaacaccattgccccaaacgctgggtcacggatg
acagagacggtgatgccagaagacctcgttgaagccctgaagccagagtatgtggcaccg
ctggtcctttggctttgccatgagagctgtgaggaaaatggtggcttgtttgaggttgga
gcaggatggattggaaaattgcgctgggagaggaccctgggagccattgtcaggaagcgg
aatcagcccatgactcccgaggcagtgagggacaactgggtgaagatctgtgacttcagc
aatgccagcaagccgaagagcattcaagagtccacaggtggtataatcgaagttttacat
aaaatagattcagaaggaatctcacaaaatcacaccggtcaagtggcatctgcagatgca
tcaggatttgctggcgtcgttggccacaaacttccttcattttcttcttcatatacggaa
ctgcagtgcattatgtatgccctcggagtaggagcttcagtcaaaaatccaaaggacttg
aagtttgtttatgaagggagtgctgacttctcctgtttgcctacatttggagtcattgtc
gctcagaagtccttgatgagtggaggcttagcagaggttcctgggctgtcaatcaacttt
gcaaaggttcttcatggggagcagtacttggagttgtataagccacttccccgatcaggg
gaattaaaatgtgaagcagttattgctgacatcctggataaaggctctggcatagtgatt
gttatggacgtctattcttattctggcaaggaacttatatgctataatcagttctctgtc
ttcgttgttggctctggaggctttggtggaaaacggacatcagaaaaactcaaagcagct
gtagccgtaccaagtcggcctccagatgctgtactgagagataccacttcactgaatcag
gccgctctgtaccgcctcagtggagactcgaatcctttacacattgacccgagctttgcg
agcattgccggttttgagaaacccatattacacggattatgtacttttgggttttctgca
aggcatgttttacagcagtttgcggataatgatgtgtcaagattcaaggccattaaggtt
cgttttgccaaaccagtgtatccaggacaaactctacaaactgagatgtggaaggaagga
aacagaattcattttcaaaccaaggtccaagagactggagacattgtcatttccaatgca
tatgtggatcttgttcctacatctggagtttccgctcagacaccttctgagggtggagca
ctgcagagtgctcttgtatttggggaaataggtcgacgcctcaaggatgttggacgtgag
gtggtaaagaaagtaaatgctgtatttgaatggcatatcacgaaaaatgggaatgttgca
gccaagtggaccattgacctgaagaacggctctggagaggtttaccaaggccctgccaaa
ggctctgctgacacgaccatcacaatttctgatgaggatttcatggaagtggtcctgggc
aagcttaacccacagaatgccttcttcagtggcagactgaaggcccgaggaaacatcatg
ctgagccagaagctacagatgattctgaaagactatgccaagctctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (5)   
   KEGG MODULE (3)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (11)   
   KEGG ENZYME (2)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
3D Structure (1)   
   PDB (1)   
Protein domain (9)   
   Pfam (9)   
All databases (71)   

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