KEGG   Rattus norvegicus (rat): 81515
Entry
81515             CDS       T01003                                 
Symbol
Lyn
Name
(RefSeq) tyrosine-protein kinase Lyn isoform A
  KO
K05854  tyrosine-protein kinase Lyn [EC:2.7.10.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04062  Chemokine signaling pathway
rno04064  NF-kappa B signaling pathway
rno04611  Platelet activation
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno04730  Long-term depression
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05169  Epstein-Barr virus infection
rno05203  Viral carcinogenesis
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    81515 (Lyn)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    81515 (Lyn)
   04662 B cell receptor signaling pathway
    81515 (Lyn)
   04664 Fc epsilon RI signaling pathway
    81515 (Lyn)
   04666 Fc gamma R-mediated phagocytosis
    81515 (Lyn)
   04062 Chemokine signaling pathway
    81515 (Lyn)
  09156 Nervous system
   04730 Long-term depression
    81515 (Lyn)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    81515 (Lyn)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    81515 (Lyn)
   05169 Epstein-Barr virus infection
    81515 (Lyn)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    81515 (Lyn)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    81515 (Lyn)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    81515 (Lyn)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     81515 (Lyn)
Protein kinases [BR:rno01001]
 Non-receptor tyrosine kinases
  SRC family
   81515 (Lyn)
Membrane trafficking [BR:rno04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    81515 (Lyn)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 SH3_3 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 81515
NCBI-ProteinID: NP_110484
RGD: 621017
Ensembl: ENSRNOG00000008180
UniProt: Q07014 A6JFK8
Position
5:21437127..21553097
AA seq 512 aa
MGCIKSKRKDNLNDDGVDMKTQPVRNTDRTIYVRDPTSNKQQRPVPESQLLPGQRFQAKD
PEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSSKREGFIPSNYVAK
VNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVI
KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAW
EIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSAQAFLEEANLMKTLQHD
KLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQIAEGMAYIER
KNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCF
TIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCW
KESAEERPTFDYLQSVLDDFYTATEGQYQQQP
NT seq 1539 nt   +upstreamnt  +downstreamnt
atgggatgtattaaatcaaaaaggaaagacaatctgaatgacgatggagtagatatgaag
actcaaccagtacgtaatactgaccgaactatttatgtgagagatccaacgtccaataaa
cagcaaaggccagttcctgaatctcaacttttaccaggacagagatttcaagcaaaagat
ccagaggagcaaggggacattgtggtggccttgtatccctatgatggcatccacccagac
gacttgtctttcaagaaaggagaaaagatgaaagttctggaagagcacggggagtggtgg
aaagctaagtccctttcatcaaagagagaaggcttcatccccagcaactacgtggccaag
gtcaacaccttagaaaccgaagagtggttcttcaaggacataacaaggaaagatgcagaa
cgacagcttctggcaccagggaacagtgccggggctttcctgatcagagaaagtgaaact
ttaaagggaagcttctctctttccgtcagagattacgaccctatgcatggcgacgtcatt
aagcactacaaaatcagaagcctggacaatggtggttattacatctctccgaggatcact
tttccctgtatcagtgacatgattaagcattaccaaaagcagtctgatggtctatgcaga
agactggagaaggcatgcatcagtcccaaaccacagaagccatgggataaagatgcttgg
gagatcccccgggagtccattaagctggtgaaaaaactcggcgcagggcagttcggggaa
gtctggatgggttactataacaacagcacaaaagtggctgtaaagaccctcaagcctggc
accatgtctgctcaagcattcctggaagaggccaacctcatgaagaccttgcagcatgac
aagctagtgcggctgtatgccgtggtcaccaaggaggagcccatctacatcattaccgag
ttcatggccaagggtagcttgctggatttcctcaagagtgacgaaggcagcaaggttctg
ctcccgaaactcattgacttttcagctcagattgcagaaggcatggcgtacatcgagcgg
aagaactacatccaccgcgatctgcgagctgccaacgtgctggtctctgagtctctcatg
tgcaagattgcagactttggcctcgcgagagtaatcgaagataatgaatacacagcgagg
gaaggtgccaagttccctatcaagtggacggctccagaggccatcaacttcggctgcttc
actatcaagtctgacgtgtggtccttcggaattctcctgtacgagatcgtcacctatggg
aagattccctacccagggagaactaacgcagatgtgatgaccgcactgtcacaggggtac
cgaatgccacgaatggagaactgtccagatgagctctatgacatcatgaaaatgtgctgg
aaggaatcagcagaggagaggccaacctttgactacttacagagtgtactggatgacttc
tacactgccacggaagggcagtatcagcagcagccatag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (15)   
   RefSeq(nuc) (3)   
   GenBank (6)   
   EMBL (6)   
Protein domain (9)   
   Pfam (9)   
All databases (53)   

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