KEGG   Rattus norvegicus (rat): 81924
Entry
81924             CDS       T01003                                 
Symbol
Cyp8b1
Name
(RefSeq) 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase precursor
  KO
K07431  sterol 12-alpha-hydroxylase [EC:1.14.14.139]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00120  Primary bile acid biosynthesis
rno01100  Metabolic pathways
rno03320  PPAR signaling pathway
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    81924 (Cyp8b1)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    81924 (Cyp8b1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:rno00199]
    81924 (Cyp8b1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.139  5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
     81924 (Cyp8b1)
Cytochrome P450 [BR:rno00199]
 Cytochrome P450, animal type
  CYP8 family
   81924 (Cyp8b1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 81924
NCBI-ProteinID: NP_112520
RGD: 71016
Ensembl: ENSRNOG00000019481
UniProt: Q9WVT5
Position
8:complement(130455622..130457592)
AA seq 499 aa
MLWGSVLGALLMAVGCLCLSLLPRHRRPWEPPLDKGFVPWLGHTMAFRKNMFEFLKGMRA
KHGDVFTLQLGGQYFTFVMDPLSFGPIIKSTQKVLDFVTYARELVFKVFGYQSMDEDHQM
LHIASTKHLMGQGLEDLNRAMLDSLSLVMLGPKGRSLGARSWCEDGLFHFCYSILFKAGF
LSLFGCTKDKEQDLDEADELFRKFRRFDLLFPRFVYSLLGPREWVEVSQLQRLFHQRLSV
EQNLEKDGISNWLGFMLRFLRERGMASSMQDKFNFMMLWASQGNTGPTCFWALLFLLKHQ
DAMKAVREEATRVLGEARLEAETSFAFTLSALKCTPVLDSVMEETLRLCATPTLLRVVQE
DYVLKMASGQEYQIRRGDKVALFPYLSVHMDPDIHPEPTTFKYNRFLNPDGTRKVDFYKS
GKKIHHYNMPWGSGVSICPGRFFALSEMKTFVLLMVMYFDFELVDPDVPVPPIDPRRWGF
GTSQPSHEVRFRYRLKPMQ
NT seq 1500 nt   +upstreamnt  +downstreamnt
atgctgtggggttcagtgctaggggccctgctcatggctgtcggttgcctctgcctctcc
ttgctgcccaggcaccgcaggccctgggagccacctctggacaaggggtttgtgccctgg
ctgggtcacaccatggccttccggaagaatatgtttgaattcctgaagggaatgcgggcc
aagcacggggacgtgttcacactgcagctgggaggccagtacttcacctttgtcatggat
cccctctcctttggccccatcattaagagcacgcagaaagtgctagacttcgtgacgtac
gctcgggaactggtgttcaaggtgtttgggtaccagtccatggatgaggaccaccagatg
ctgcacatagccagtaccaagcatctgatgggacaaggcttggaggacctcaaccgggcc
atgctggacagcctgtccttggtgatgctaggacccaaaggccggagtctgggtgccagg
tcctggtgtgaggacggcctcttccacttctgctacagcatcctgtttaaggctggcttc
ctgagcttgtttggctgcaccaaggacaaggagcaggacctggatgaggccgatgagctg
ttcaggaagttccgcagatttgacctacttttccccaggtttgtctactccctgctgggg
ccccgggagtgggtagaagtgagccagctgcagcgtctcttccaccagagactctctgtg
gagcaaaacctggagaaagacggcataagtaactggttgggcttcatgcttcggtttctg
agggagcgagggatggcttcatccatgcaggacaaatttaactttatgatgctctgggcc
tcccaggggaacacggggcccacctgtttctgggccctcctgttcctgctgaagcatcag
gacgccatgaaggctgtgcgagaggaagccactcgggtcctgggtgaggccaggttggaa
gccgagacatccttcgctttcactctcagtgccctgaaatgcactccagtgctggacagc
gtgatggaagagactcttcgtctctgtgccacccccaccctcctcagggtggtgcaggag
gattatgtcctaaagatggccagtgggcaagagtaccagatccgccgtggagataaggtg
gctctcttcccctatctctcagtacacatggaccccgacatccatcccgagcccacgacc
ttcaagtacaatcggttcctcaaccctgatggcacccggaaagtggacttctacaagtca
ggcaagaagatccaccactacaacatgccctgggggtcgggtgtctccatatgtcccggc
aggttctttgccctcagtgagatgaagacctttgtcctccttatggtcatgtactttgac
tttgaactggtggaccctgacgtgcctgtgccccctatcgacccaaggcgctggggcttc
ggcacctcccagcccagccacgaggtacgctttcgctaccgcctgaagcccatgcagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (1)   
   Pfam (1)   
All databases (33)   

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