KEGG   Rattus norvegicus (rat): 84350
Entry
84350             CDS       T01003                                 
Symbol
Dnmt1
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 1
  KO
K00558  DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00270  Cysteine and methionine metabolism
rno01100  Metabolic pathways
rno05206  MicroRNAs in cancer
Module
rno_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    84350 (Dnmt1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    84350 (Dnmt1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    84350 (Dnmt1)
   03032 DNA replication proteins [BR:rno03032]
    84350 (Dnmt1)
   03036 Chromosome and associated proteins [BR:rno03036]
    84350 (Dnmt1)
  09183 Protein families: signaling and cellular processes
   02048 Prokaryotic defense system [BR:rno02048]
    84350 (Dnmt1)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     84350 (Dnmt1)
Transcription factors [BR:rno03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    84350 (Dnmt1)
DNA replication proteins [BR:rno03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    84350 (Dnmt1)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    84350 (Dnmt1)
Prokaryotic defense system [BR:rno02048]
 Restriction and modification system (R-M system)
  Type II R-M system
   DNA methyltransferases
    84350 (Dnmt1)
SSDB
Motif
Pfam: BAH DNA_methylase DNMT1-RFD DMAP_binding zf-CXXC HTH_12
Other DBs
NCBI-GeneID: 84350
NCBI-ProteinID: NP_445806
RGD: 620979
Ensembl: ENSRNOG00000039859
UniProt: A6JNM5 F1LQT9
Position
8:complement(27716797..27763405)
AA seq 1621 aa
MPARTAPARVPALASPAGSLPDHVRRRLKDLERDGLTEKECVKEKLNLLHEFLQTEIKSQ
LCDLETKLHKEELSEEGYLAKVKTLLNKDLCLENGTLSLTQKANGCPANGSRPTWKAEMA
DSNRSPRSRPKPRGPRRSKSDSETMIEASSSSVATRRTTRQTTITSHFKGPAKRKPKEDS
EKGNANESAAEERDQDKKRRVAGTESRASRAGESVEKPERVRPGTQLCQEEQGEQEDDRR
PRRQTRELASRRKSREDPDREARPGTHLDVDDDDEKDKRSSRPRSQPRDLATKRRPKEEV
EQITPEPPEGKDEDEREEKRRKTTRKKPEPLSIPVQSRVERKASQGKASAIPKLNPPQCP
ECGQYLDDPDLKYQQHPVDAVDEPQMLTNEALSVFDSNSSWFETYDSSPMHKFTFFSVYC
SRGHLCPVDTGLIEKNVELYFSGVAKAIHEENPSVEGGVNGKNLGPINQWWISGFDGGEK
ALIGFSTAFAEYFLMEPSPEYAPIFGLMQEKIYISKIVVEFLQSNPDAVYEDLINKIETT
VPPSAINVNRFTEDSLLRHAQFVVSQVESYDDAKDDDETPIFLSPCMRSLIHLAGVSLGQ
RRATRRTVINSAKVKRKGPTKATTTKLVYQIFDTFFSEQIEKDDKEDKENTMKRRRCGVC
EVCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCPNLAVKEADEDEEADDDIPELPSPK
KLHQGKKKKQNKDRISWLGEPVKIEENRTYYWKVSIDEETLEVGDCVSVIPDDPSKPLYL
ARVTALWEDKNGQMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYR
GPSPNWAMEGGMDPEAMLPGAEDGKTYFYQFWYSQDYARFESPPKTQPTEDNKHKFCLSC
IRLAELRQKEMPKVLEQLEEVDGRVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKMASPM
KRSKRDPVNENLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIHCGKKKGGKVNEADIKI
RLYKFYRPENTHKSIQATYHADINLLYWSDEEAVVDFSDVQGRCTVEYGEDLLESIQDYS
QGGPDRFYFLEAYNSKTKSFEDPPNHARSPGNKGKGKGKGKGKGKPQVSEPKEPEAAIKL
PKLRTLDVFSGCGGLTEGFHQAGISETLWAIEMWEPAAQAFRLNNPGTTVFTEDCNVLLK
LVMAGEVTNSLGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCD
YYRPRFFLLENVRNFVSFRRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIIL
AAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPE
IQNGASAPEISYNGEPQSWFQRQLRGSHYQPILRDHICKDMSALVAARMRHIPLSPGSDW
RDLPNIQVRLRDGVITNKLRYTFHDTKNGCSSTGALRGVCSCAEGKTCDPASRQFNTLIP
WCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQ
GFPDTYRLFGNILDRHRQVGNAVPPPLAKAIGLEIKLCLLASAQESASAAVKGKEETTTE
D
NT seq 4866 nt   +upstreamnt  +downstreamnt
atgccagcacgaacagctccagcccgagtgcctgcacttgcctccccggcaggctcgctc
cccgaccatgtccgcaggcggctcaaagacttggaaagagatggcttaacagaaaaggag
tgtgtgaaagagaaattgaacttactgcatgaattcctgcaaacagaaataaaaagccag
ctatgcgacttggaaaccaaactacataaagaggaattgtctgaggaaggctacctggct
aaagtcaagacccttctaaataaggatttgtgcctggagaacggaacactctctctcact
cagaaagccaacggttgtcctgccaacgggagtcggccaacctggaaagcagaaatggca
gactcaaaccgatccccaagatccaggcccaagcctcggggacccaggaggagcaagtcg
gacagtgagaccatgattgaagcttcatctagttcggtggctacgaggagaaccaccagg
cagaccaccatcacgtctcacttcaagggtcccgctaaacggaaacccaaggaagactct
gaaaagggaaacgcaaatgaatctgctgcagaggagagagaccaggataagaaacgcaga
gtcgcaggcacagagagtcgtgccagtcgtgccggagagtctgtggagaaacctgaacga
gtaaggccaggaacccagctgtgtcaggaagagcaaggtgaacaggaagatgacaggaga
cctcgacgtcaaaccagagagctagcatcaaggcggaaatcaagggaggacccagacaga
gaagcaaggccaggaactcacttggatgtggacgatgacgatgaaaaggacaaaagaagt
tccaggcccagaagccagcccagagatctagccaccaaacggagacccaaggaagaagta
gagcagatcactccagagcctcccgagggcaaagatgaggacgaaagggaggagaagaga
cgaaaaacgacacgtaaaaagccggaaccactcagcattcccgtacagagcagagtggag
agaaaagcctctcagggcaaagcaagtgcaatcccaaagctcaacccgccacagtgccct
gagtgtggccagtacctagatgaccctgacctgaagtaccagcagcaccctgtggatgct
gtggatgaaccccagatgctgaccaatgaggcactgtccgtctttgactccaactcgtct
tggtttgagacctatgattcctctcccatgcataagttcactttcttcagtgtgtattgc
agtcgcggtcacttgtgtcctgtcgacactggtctcattgagaagaacgttgaactctac
ttttctggtgttgccaaagcaattcatgaagaaaatccgtctgtggaaggtggtgttaat
ggcaagaacctggggccaatcaatcagtggtggatcagtggctttgacggtggcgagaag
gcgctcattggcttttctaccgcatttgctgaatactttctgatggagcccagcccagag
tatgcaccaatatttgggctgatgcaggagaaaatttacatcagcaagattgtggtcgag
ttcttgcagagcaatcctgacgctgtctatgaagacttgatcaataagatcgagaccact
gttcctccttctgccatcaatgtgaaccggttcaccgaggactccctcctacgccatgcc
cagtttgtggtgagccaggtagaaagttacgacgacgctaaggacgatgatgagacgccc
atcttcttgtctccctgtatgaggtccctgatccatttggctggtgtctcgctgggacag
aggcgagcaacaaggcgcacggtcatcaattctgccaaagtgaagcgcaaggggcccaca
aaagccaccaccaccaagctggtctatcagatcttcgacactttcttctcggagcagatc
gagaaggatgacaaggaggacaaagagaacaccatgaagcgccgccggtgtggtgtctgt
gaggtctgtcaacagcctgagtgtgggaagtgcaaggcgtgcaaagacatggttaagttt
ggtggcaccggacggagtaaacaggcttgcctcaagaggaggtgtcctaacttggccgta
aaggaggcagatgaagacgaagaagctgatgatgatataccagagttgccgtcacccaaa
aagttgcaccaagggaagaagaagaaacagaataaggatcgcatctcctggctcggggag
cctgtgaagatcgaagagaacagaacttactattggaaggtgagcatcgacgaagagact
ctggaggtgggcgactgcgtctcggtcattccggatgatccctccaaaccactgtatcta
gccagggtcacagcactgtgggaagacaagaacgggcagatgttccatgcacactggttc
tgcgcggggacagacacggtcctcggagccacctctgaccctctggagctgttccttgta
ggcgagtgtgaaaacatgcaactttcctacatccacagcaaggtcaaggtcatctacaga
gggccttccccaaactgggccatggagggaggcatggaccctgaggccatgttgccgggg
gctgaggatgggaagacctacttctaccagttctggtacagccaggactacgcaaggttt
gagtccccacccaagacccagccgacggaggacaataagcacaagttctgcctatcttgt
atccggctggctgagctgagacaaaaagaaatgcccaaagtcctggaacaacttgaggag
gtggacggccgggtctactgcagttctatcaccaagaacggtgttgtctaccgactgggt
gacagtgtgtacctgcctcctgaggcctttactttcaacatcaaaatggccagccccatg
aaacgctctaagagggaccctgtgaatgagaacctgtaccccgagcattaccgcaagtat
tccgactacatcaaaggaagcaacctggacgcccctgaaccctatcggattggtcggata
aaagagatccactgtggcaagaagaaaggtggcaaggtcaatgaggcagacatcaagatc
aggctctacaagttctataggcctgagaacacccacaagtccatccaggcaacctaccac
gccgacatcaacctgctctactggagcgatgaggaagccgtggtggacttcagcgacgtg
caaggccgctgcaccgtggagtacggagaggacctgcttgagagcatccaggattactca
cagggcggccccgaccgcttctactttctcgaggcctacaattcaaagactaaaagcttt
gaagaccctccgaaccatgcccgcagccctgggaacaaaggcaaaggaaaggggaaaggg
aaagggaagggaaaacctcaggtatcagagcccaaagagcccgaggcagccatcaaactg
cctaagctgcggaccctggatgtgttttctggctgtggaggattaacagaaggattccac
caagcaggcatctcggagacgctgtgggccatcgagatgtgggaaccagcagcccaggca
tttcggctgaacaaccctggcaccacggtgttcacagaggactgcaacgtgcttctcaag
ctggtcatggctggtgaggtgaccaactctctgggccagaggctgccacagaagggcgat
gtggagatgctgtgtggtgggccgccctgccagggcttcagtggcatgaaccgtttcaac
tctcgtacttactccaagttcaaaaactccctcgtggtctccttcctcagctactgtgac
tactaccggcctcggttcttcctcttggagaatgtcaggaacttcgtgtccttcaggcgc
tccatggtgctgaagctcacactgcgctgcctggtccgcatgggctaccagtgcaccttc
ggtgtgctccaggctggacagtatggtgtggcccagacacgaaggagggccatcatcttg
gctgcagcccctggagagaagctgcctctgttcccagaacctctacacgtgtttgccccc
cgtgcctgccagctgagtgttgtggtggacgacaagaagttcgttagcaacattacaagg
ctaagctcgggtcccttccgaaccatcacggtgcgagataccatgtctgacctccctgag
atccagaatggagcctcagcccccgagatctcctacaatggagagccacagtcctggttc
cagaggcagctgcgagggtcgcactaccagcccatcctcagggaccatatctgcaaggac
atgagcgcgctggtggctgcccgtatgcggcacatcccgctgtccccaggatcggattgg
cgtgacctgcccaacatacaagtgcggctgagagatggcgtcataaccaataaacttcgc
tacactttccacgacacgaagaacggctgcagcagcaccggggccctgcgtggggtctgc
tcctgtgcggaaggcaagacctgcgaccctgcttccagacaattcaacacgctcatcccc
tggtgcctgccgcacactgggaaccggcacaaccactgggctggcctctacgggcgtctg
gagtgggatggcttcttcagtaccaccgtcaccaaccctgagcccatgggcaagcaaggc
cgggtgctccatcccgagcagcaccgggtcgtgagtgtgcgggaatgtgctcgctcccaa
ggctttccagatacctaccggttattcggcaacatcctggacagacaccggcaggtgggg
aacgctgtgccaccaccactggccaaagccatcggcctggagattaagctctgtctgctg
gccagcgctcaggagagtgcctcagctgcagttaaaggaaaggaggagactactaccgag
gactag

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (32)   
   RefSeq(nuc) (2)   
   GenBank (15)   
   EMBL (15)   
Protein domain (6)   
   Pfam (6)   
All databases (65)   

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