KEGG   Rattus norvegicus (rat): 84489
Entry
84489             CDS       T01003                                 
Symbol
Fgfr3
Name
(RefSeq) fibroblast growth factor receptor 3 precursor
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno04010  MAPK signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04020  Calcium signaling pathway
rno04144  Endocytosis
rno04151  PI3K-Akt signaling pathway
rno04550  Signaling pathways regulating pluripotency of stem cells
rno04810  Regulation of actin cytoskeleton
rno05200  Pathways in cancer
rno05206  MicroRNAs in cancer
rno05219  Bladder cancer
rno05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    84489 (Fgfr3)
   04014 Ras signaling pathway
    84489 (Fgfr3)
   04015 Rap1 signaling pathway
    84489 (Fgfr3)
   04020 Calcium signaling pathway
    84489 (Fgfr3)
   04151 PI3K-Akt signaling pathway
    84489 (Fgfr3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    84489 (Fgfr3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    84489 (Fgfr3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    84489 (Fgfr3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    84489 (Fgfr3)
   05206 MicroRNAs in cancer
    84489 (Fgfr3)
   05230 Central carbon metabolism in cancer
    84489 (Fgfr3)
  09162 Cancer: specific types
   05219 Bladder cancer
    84489 (Fgfr3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    84489 (Fgfr3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    84489 (Fgfr3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:rno04090]
    84489 (Fgfr3)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     84489 (Fgfr3)
Protein kinases [BR:rno01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   84489 (Fgfr3)
CD molecules [BR:rno04090]
 Proteins
  84489 (Fgfr3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 84489
NCBI-ProteinID: NP_445881
RGD: 620714
Ensembl: ENSRNOG00000016818
UniProt: Q9JHX9
Position
14:complement(81211800..81227215)
AA seq 800 aa
MVVPACVLVFCVAVVAGVTSEPPGPEQRVGRRAAEVPGPEPSQQEQVAFGSGDTVELSCH
PPGGAPTGPTLWAKDGVGLVASHRILVGPQRLQVLNATHEDAGVYSCQQRLTRRVLCHFS
VRVTDAPSSGDDEDGEDVAEDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSI
SWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVL
ERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYV
TVLKTAGANTTDRELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELMEV
DEAGSVYAGVLSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKVSRFPLKRQVSLE
SNSSMNSNTPLVRIARLSSGEGPVLANVSELELPADPKWELSRTRLTLGKPLGEGCFGQV
VMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACT
QGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKDLVSCAYQVARGME
YLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMI
MRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSSGDD
SVFTHDLLPPGPPSNGGPRT
NT seq 2403 nt   +upstreamnt  +downstreamnt
atggtagtcccggcctgcgtgctagtgttctgcgtggcggtcgtggctggagttacttcc
gagcctcccggtccagagcagcgagttggtcggagagcggcagaggttccagggcctgaa
cctagccagcaggagcaggtggccttcggcagtggggacactgtggagctgagctgccat
ccgcctggaggtgcccccacaggccccactctctgggctaaggacggtgtggggctggtg
gcctcccaccgtatcctggtggggcctcagaggcttcaagtgctaaacgccacccatgag
gatgctggggtctacagctgccagcagcggctaacccggcgtgtgctgtgccactttagt
gtgcgtgtgacagatgctccgtcctcaggagatgacgaagatggggaggacgtggctgaa
gacacaggggctccttactggactcgaccggagcgtatggataagaaactgctggctgtg
ccagctgcaaacactgtacgcttccgctgcccagctgctggcaaccccaccccctccatc
tcctggctgaagaacggcaaagaattccgaggggagcaccgcattgggggcattaagctc
cggcaccagcagtggagcttggtcatggaaagtgtggtgccctctgaccgcggcaattac
acctgcgtggttgagaacaagtttggcagcatccggcagacgtacaccctggatgtgctg
gagcgctccccacaccggcccatcctgcaggctgggctgccagccaaccagacagccgtt
ctgggcagtgacgtggagttccactgcaaggtgtacagcgacgcacagccacacatccag
tggctgaagcacgtggaggtgaatgggagcaaggtgggccctgacggcacgccctacgtc
actgtactcaagactgcaggagctaacaccaccgacagggagctagaggttctgtccttg
cacaatgtcacctttgaggatgcgggggagtacacctgcctggcgggcaattctatcggg
ttttcccatcactctgcgtggctggtggtgctgccagccgaggaggagctgatggaagtt
gacgaggctggcagcgtgtacgcgggtgtcctcagctacggggtgggcttcttcctcttc
atcctggtggtggcggcagtgacgctctgccgtctgcgcagtcccccaaagaagggcctg
ggctcgcccaccgtgcacaaggtctctcgcttcccgcttaagcgacaggtgtccttggag
tctaattcctctatgaactccaacacacctctcgtccggattgcccggctgtcctcagga
gaaggtcctgtcctggccaatgtttctgaacttgagctgcctgctgaccccaagtgggag
ctatccaggacccggctgacactcggtaagcctcttggagaaggctgctttggacaggtt
gtcatggcagaagctattggcatcgacaaggaccgcactgccaagcctgtcaccgtggcc
gtgaagatgctgaaagatgatgccactgacaaggacctgtcggacctggtgtctgagatg
gagatgatgaaaatgattggcaagcacaagaacatcattaacctgttgggggcctgcacc
cagggtgggcccctgtatgtgctggtggagtatgcagccaagggcaacctgcgagagttc
ctccgggcacggcggcctccaggcatggattactcctttgatgcctgcaggctgccagag
gaacagctcacctgcaaggatctggtgtcctgtgcctaccaggtggcacggggcatggag
tacttggcttcccagaagtgtattcacagagacctggctgccagaaacgtgctggtgact
gaggacaatgtgatgaagattgcagactttggcctggcccgagatgtgcacaacctggat
tactacaagaagaccacaaatggccggctacctgtgaagtggatggcaccagaggccctt
tttgaccgagtctacacccatcagagtgatgtctggtcctttggtgtcctcctctgggag
atctttacactgggtgggtcaccatatcctggcatcccagtggaagagcttttcaagctg
ttgaaagagggccaccgcatggacaagccagccaactgcacacatgacctgtacatgatc
atgcgggaatgttggcatgcagtgccttcacagaggcccaccttcaagcagttggtagag
gatttagaccgcatcctcacggtgacatcaactgacgagtacttggacctctcggtgcca
tttgaacagtactcgccaggtggccaagatactcctagctccagctcgtccggggacgac
tctgtgttcacccatgacctgctacccccaggcccacccagcaatgggggacctcggacg
tga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (13)   
   KEGG PATHWAY (13)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (6)   
   RefSeq(nuc) (4)   
   GenBank (1)   
   EMBL (1)   
Protein domain (11)   
   Pfam (11)   
All databases (47)   

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