KEGG   Saccharomyces cerevisiae (budding yeast): YNL262W
Entry
YNL262W           CDS       T00005                                 
Symbol
POL2, DUN2
Name
(RefSeq) DNA polymerase epsilon catalytic subunit
  KO
K02324  DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce03030  DNA replication
sce03410  Base excision repair
sce03420  Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:sce00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    YNL262W (POL2)
   03410 Base excision repair
    YNL262W (POL2)
   03420 Nucleotide excision repair
    YNL262W (POL2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:sce03032]
    YNL262W (POL2)
   03400 DNA repair and recombination proteins [BR:sce03400]
    YNL262W (POL2)
Enzymes [BR:sce01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     YNL262W (POL2)
DNA replication proteins [BR:sce03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    YNL262W (POL2)
DNA repair and recombination proteins [BR:sce03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      YNL262W (POL2)
SSDB
Motif
Pfam: DUF1744 DNA_pol_B_exo1 DNA_pol_B DNA_pol_B_exo2 RNase_H_2 NAPRTase_C Cytochrom_c3_2 zf-DNA_Pol
Other DBs
NCBI-GeneID: 855459
NCBI-ProteinID: NP_014137
SGD: S000005206
UniProt: P21951
Structure
Position
XIV:148212..154880
AA seq 2222 aa
MMFGKKKNNGGSSTARYSAGNKYNTLSNNYALSAQQLLNASKIDDIDSMMGFERYVPPQY
NGRFDAKDIDQIPGRVGWLTNMHATLVSQETLSSGSNGGGNSNDGERVTTNQGISGVDFY
FLDEEGGSFKSTVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIRKEDLTMDNH
LLGLQKTLIKLSFVNSNQLFEARKLLRPILQDNANNNVQRNIYNVAANGSEKVDAKHLIE
DIREYDVPYHVRVSIDKDIRVGKWYKVTQQGFIEDTRKIAFADPVVMAFDIETTKPPLKF
PDSAVDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGFFTIFNENDEVALLQ
RFFEHIRDVRPTVISTFNGDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCSHM
DCFRWVKRDSYLPQGSQGLKAVTQSKLGYNPIELDPELMTPYAFEKPQHLSEYSVSDAVA
TYYLYMKYVHPFIFSLCTIIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDPIE
RFYDGHLLESETYVGGHVESLEAGVFRSDLKNEFKIDPSAIDELLQELPEALKFSVEVEN
KSSVDKVTNFEEIKNQITQKLLELKENNIRNELPLIYHVDVASMYPNIMTTNRLQPDSIK
AERDCASCDFNRPGKTCARKLKWAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKV
LTFDELSYADQVIHIKKRLTEYSRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDR
RYEFKGLAKTWKGNLSKIDPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSR
WYSMEMAGITCLTGATIIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGKK
LYLSYPCSMLNYRVHQKFTNHQYQELKDPLNYIYETHSENTIFFEVDGPYKAMILPSSKE
EGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVA
SVCNRWLDVLDSHGLMLEDEDLVSLICENRSMSKTLKEYEGQKSTSITTARRLGDFLGED
MVKDKGLQCKYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTI
IDWGYYRERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIATKEDKFKQTSLTKFF
SKTKNVPTMGKIKDIEDLFEPTVEEDNAKIKIARTTKKKAVSKRKRNQLTNEEDPLVLPS
EIPSMDEDYVGWLNYQKIKWKIQARDRKRRDQLFGNTNSSRERSALGSMIRKQAESYANS
TWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSS
ASLPNNPKTSNPAGGQLFKITLPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMD
LGASVTFRSKAMGALGKGIQQGFEMKDLSMAENERYLSGFSMDIGYLLHFPTSIGYEFFS
LFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEF
VYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLGTIRLLNQMPIVKLSLNEV
LLPQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKL
KKENIVLWWNEKAPLPDHGGIQNDFDLNTSWIMNDSEFPKINNSGVYDNVVLDVGVDNLT
VNTILTSALINDAEGSDLVNNNMGIDDKDAVINSPSEFVHDAFSNDALNVLRGMLKEWWD
EALKENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVY
ADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGL
ACIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNSGTQR
PTQIVNVKKQDKEDSVENSLNGFSHLFSKPLMKRVKKLFKNQQEFILDPQYEADYVIPVL
PGSHLNVKNPLLELVKSLCHVMLLSKSTILEIRTLRKELLKIFELREFAKVAEFKDPSLS
LVVPDFLCEYCFFISDIDFCKAAPESIFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQ
DLRCSRCHKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADL
TI
NT seq 6669 nt   +upstreamnt  +downstreamnt
atgatgtttggcaagaaaaaaaacaacggaggatcttccactgcaagatattcagctggc
aacaagtacaacacactctcaaataattatgcgcttagcgcgcaacagctcttaaatgct
agtaagatcgatgacatcgattcgatgatgggatttgaaagatacgtaccgccgcaatac
aatggcaggtttgatgcgaaggatatagatcagattccaggccgcgtagggtggctgacg
aacatgcacgcaacgctggtctctcaggaaaccttatccagtggtagtaatggcggcggc
aattcgaatgacggagaacgtgtaacgaccaaccaaggtatttccggagttgacttctac
tttttagatgaagagggtgggagcttcaagtcgacagttgtctatgacccatacttcttt
attgcgtgtaacgatgaatcaagagtaaatgatgtggaggaactagtgaaaaaatatctg
gaatcttgtctcaaaagcttacaaatcattagaaaggaagatcttaccatggacaatcac
cttttagggctgcagaagacacttattaagttatcatttgtaaattccaatcagttattc
gaggccaggaaactcctgaggccaatcttgcaggataatgccaataataatgtgcaaaga
aatatatataacgttgctgcaaatggctcggaaaaagttgacgccaaacatctgatcgaa
gatatcagggaatatgatgtgccgtatcatgtccgagtatctatagacaaggacattaga
gtcggtaaatggtataaggtaactcaacagggattcattgaagatactaggaaaattgca
tttgccgaccctgtggtaatggcatttgatatagaaaccacgaagccgcctttaaaattc
ccggattccgccgtagatcaaataatgatgatttcgtatatgatcgatggggaaggtttt
ttgataacaaatagggagataatctctgaggatattgaagactttgagtatacaccgaaa
ccggagtatcctggttttttcaccatatttaacgaaaacgatgaagtggcgcttctacaa
aggttttttgaacatataagagatgtacgacccactgttatatccaccttcaatggtgac
tttttcgattggccttttatacataacagaagtaagattcacggcttggacatgttcgat
gaaattggtttcgctccagatgctgaaggtgagtacaagtcctcatactgctctcacatg
gattgtttccgttgggtgaagcgtgattcttatttaccacaaggttcccagggtttaaaa
gctgttactcaatctaagctaggttataacccaattgaactggatcccgaattaatgacg
ccgtatgcatttgaaaagccacagcacctttccgaatattctgtttccgatgcagtcgct
acgtattacctttacatgaaatatgttcatccttttatcttttccctttgtactattatt
cctttgaacccggatgaaacattgagaaagggtaccggtactttgtgtgaaatgttgttg
atggttcaagcttatcaacataatattcttctaccaaataagcatacagatcccattgag
aggttctatgatggacatcttctagaatccgagacttacgtgggtggacatgtggagtca
ttagaagctggtgtttttaggagtgatttgaagaatgaattcaagatagatccttctgcc
attgatgaattattacaagaattaccagaagctttgaaatttagtgtggaagttgaaaat
aagtccagtgtagataaagtaacgaattttgaggaaataaaaaaccagataacgcagaaa
ttattagagttgaaggaaaacaatataagaaacgaactacctttgatctatcatgtagat
gtcgcctctatgtacccaaacatcatgactacaaatagactacaaccagatagtatcaaa
gcagagcgcgattgtgctagttgcgattttaatagacccggaaaaacctgtgcaagaaag
ttaaaatgggcttggagaggagaattctttcccagtaagatggatgagtataacatgatc
aagcgtgcattacaaaatgagacttttcccaacaaaaacaagttttctaaaaagaaagtt
ttgacatttgatgaactaagttacgcagaccaagttatccacataaaaaaacgtttaact
gaatattcaaggaaagtttatcatagggttaaagtatcagaaattgtcgaacgagaagcc
attgtctgccaaagagaaaatccattctacgtcgataccgtgaaatcctttcgtgatagg
cgttacgaattcaaaggtttagccaagacttggaagggaaatctgtccaaaattgaccca
tctgataagcatgcgagagacgaggccaaaaagatgattgtgctttatgactcattacaa
ttagctcacaaagttattttgaattcgttttatgggtatgttatgaggaaaggctctcgt
tggtattccatggaaatggcggggattacgtgtttaacaggtgccacgatcattcaaatg
gcgagagctttagtagaaagggtaggaagaccattagaattagatactgatggtatttgg
tgtatcttaccaaaatctttccctgaaacttacttttttacattagaaaatggtaaaaag
ctttatctctcctacccatgttccatgctgaattacagagttcaccaaaagtttacgaat
caccaataccaagaattaaaagacccattgaactatatatatgagacgcacagtgaaaac
acgatttttttcgaagttgacggaccatataaggccatgattttgcctagttccaaggaa
gaaggaaaaggtataaagaaaagatatgctgtcttcaatgaagacggctcacttgctgaa
ctgaaaggttttgaattgaagaggcgtggtgaattacaactaataaaaaattttcaaagt
gatattttcaaggtctttttggaaggtgatacattagaaggatgttacagtgctgtagca
agcgtatgtaaccgttggttagatgttcttgattcacatggtcttatgttagaagatgaa
gacttggtcagtttgatttgtgaaaatagaagtatgtcaaaaactttaaaggaatatgaa
gggcaaaaatctacttctattacgacggcaaggagattgggggattttttgggtgaagat
atggtaaaagataaaggtctacaatgtaaatatattattagttcaaaacctttcaatgca
cctgttactgaacgagccattccagtcgcaatattttcagcggacattcccatcaaaagg
tcttttctgaggcgatggacattagatccatctttggaagatctggatatcagaaccata
atcgattggggttattatagagaaagacttggatctgctatacaaaagataattactatt
ccagcagcattacaaggggtttccaatcctgttccaagggttgaacatccagattggcta
aaaagaaaaatcgctacaaaggaggataagtttaagcagacttcactaaccaaatttttt
tcgaagacaaagaatgtaccaacaatgggcaagataaaagatatcgaggatttgtttgaa
ccaactgtagaagaagataacgccaaaattaaaattgcaagaactactaaaaagaaagcc
gtatccaagaggaaaagaaatcagcttacaaatgaagaagatccactagtattgccctcg
gagattccttccatggacgaggactatgttgggtggctaaattatcaaaaaattaaatgg
aaaatccaagcaagagatagaaagcgtcgagaccaattatttggtaatacaaacagctcc
cgtgaaagaagtgcactaggaagtatgattaggaagcaagctgaatcatatgcgaactcc
acttgggaggtcttacaatacaaggattccggtgagccaggggttttggaagtatttgta
acaattaatggcaaagtccagaacatcaccttccatataccaaaaactatttatatgaaa
ttcaaatctcaaacaatgccgctacaaaagattaagaattgccttattgaaaaatcttct
gcatcgttaccaaataatcccaaaacgtctaatccagcaggcggtcagctattcaaaatt
actctaccggaatctgtctttctggaagaaaaggaaaactgcactagtatcttcaacgat
gaaaatgtacttggtgtatttgagggcactatcactcctcatcaaagagcgatcatggat
ttgggagcttcggtaacgttccgctcaaaagcaatgggtgcgttaggcaagggaatacag
cagggttttgaaatgaaggatctttcaatggcggaaaatgaaaggtatctgagtggattt
tcaatggacattggctatttactacatttcccaacatcaattgggtatgaatttttttca
ttattcaagtcatggggagatactattactatattagttttgaaaccatccaaccaggct
caggaaataaatgcctcatcattaggacaaatatacaaacaaatgtttgaaaaaaagaaa
ggtaaaatagaaacatattcttacttggttgatattaaagaagatatcaattttgagttt
gtatattttacagatatctcaaaattgtacagaagactatcacaggaaactactaaatta
aaagaagaaagaggtctgcagtttttactcttgttacaatctccgtttatcactaagctc
ttaggcacaatccggcttctaaaccagatgcccattgttaagctttccttgaatgaagtt
cttctaccccaattgaactggcaaccgacattattgaagaaacttgttaaccacgtttta
tccagtggttcgtggatttctcacttgatcaagttatcccagtatagtaacattccaatc
tgtaatttgaggctggatagtatggattatattattgatgttctttatgcaagaaaacta
aaaaaagagaacatcgtgctttggtggaatgagaaagctccacttccagatcatggaggc
attcaaaatgattttgatttaaatacatcatggataatgaatgattcagaatttcccaaa
attaataactcaggtgtgtatgacaatgtagttctcgatgttggtgttgataatttaaca
gtgaacacaattttgacatcagcattaatcaatgatgctgaaggcagtgatctagttaac
aataatatgggtatagatgacaaagatgccgttattaactcgccatctgaattcgtgcac
gacgccttttctaatgacgctttgaatgttttaagaggtatgttaaaggagtggtgggat
gaggccctaaaagaaaattcaaccgcagatttgttggtaaattccctggcaagttgggtt
caaaacccgaatgcgaaactattcgacggattactaagatatcacgttcataacttaaca
aaaaaagccttacttcaattagtaaatgaatttagtgcacttggctcaactattgtatat
gcagacaggaatcaaattctaataaagacaaacaagtactcacctgaaaactgttacgcc
tacagccaatatatgatgaaggcagttagaacaaatccaatgtttagttatctggactta
aatatcaaacgttattgggatctgctaatatggatggataagtttaattttagtggatta
gcatgtattgaaatagaggaaaaggaaaatcaggattataccgctgtttcgcaatggcaa
ctaaagaagtttctgtcaccaatatatcagcccgaatttgaggattggatgatgatcata
ttggatagtatgctaaagacaaagcagagctatctaaaattgaattcagggacgcaaaga
cctacccaaatagttaatgtaaaaaaacaagataaggaagatagtgttgaaaactcgttg
aacggattttctcaccttttttccaaaccactaatgaaaagagtcaaaaagctttttaaa
aaccagcaagagttcattttagatcctcagtatgaggcagactatgttattcctgttctt
cctggttcccatctgaatgtgaaaaatccccttctagaacttgtcaaatcactctgccat
gtcatgttactttcaaagagtacaattttagaaatcaggaccctgagaaaagaactgctg
aagatatttgaattgcgtgagtttgctaaagtagcggaattcaaagatccaagtttgagt
ctcgtggtgccggattttttatgtgaatactgttttttcatttctgatattgacttttgt
aaggcagctcctgaatctattttttcatgcgtcagatgtcacaaagcctttaatcaagta
ttgttgcaagaacacctgattcaaaaactacgttctgatatcgaatcctatttaattcaa
gatttgagatgctccagatgtcataaagtgaaacgtgactatatgagtgcccactgtcca
tgtgccggcgcgtgggaaggaactctccccagagaaagcattgttcaaaagttaaatgtg
tttaagcaagtagccaagtattacggttttgatatattattgagttgtattgctgatttg
accatatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (74)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (69)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (29)   
   PDB (29)   
Protein domain (8)   
   Pfam (8)   
All databases (124)   

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