KEGG   Saccharomyces cerevisiae (budding yeast): YCL030C
Entry
YCL030C           CDS       T00005                                 
Symbol
HIS4
Name
(RefSeq) trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase
  KO
K14152  phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00340  Histidine metabolism
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
sce01230  Biosynthesis of amino acids
Module
sce_M00026  Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00340 Histidine metabolism
    YCL030C (HIS4)
Enzymes [BR:sce01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.23  histidinol dehydrogenase
     YCL030C (HIS4)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19  phosphoribosyl-AMP cyclohydrolase
     YCL030C (HIS4)
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.31  phosphoribosyl-ATP diphosphatase
     YCL030C (HIS4)
SSDB
Motif
Pfam: Histidinol_dh PRA-CH PRA-PH ATP-cone
Other DBs
NCBI-GeneID: 850327
NCBI-ProteinID: NP_009900
SGD: S000000535
UniProt: P00815
Position
III:complement(65934..68333)
AA seq 799 aa
MVLPILPLIDDLASWNSKKEYVSLVGQVLLDGSSLSNEEILQFSKEEEVPLVALSLPSGK
FSDDEIIAFLNNGVSSLFIASQDAKTAEHLVEQLNVPKERVVVEENGVFSNQFMVKQKFS
QDKIVSIKKLSKDMLTKEVLGEVRTDRPDGLYTTLVVDQYERCLGLVYSSKKSIAKAIDL
GRGVYYSRSRNEIWIKGETSGNGQKLLQISTDCDSDALKFIVEQENVGFCHLETMSCFGE
FKHGLVGLESLLKQRLQDAPEESYTRRLFNDSALLDAKIKEEAEELTEAKGKKELSWEAA
DLFYFALAKLVANDVSLKDVENNLNMKHLKVTRRKGDAKPKFVGQPKAEEEKLTGPIHLD
VVKASDKVGVQKALSRPIQKTSEIMHLVNPIIENVRDKGNSALLEYTEKFDGVKLSNPVL
NAPFPEEYFEGLTEEMKEALDLSIENVRKFHAAQLPTETLEVETQPGVLCSRFPRPIEKV
GLYIPGGTAILPSTALMLGVPAQVAQCKEIVFASPPRKSDGKVSPEVVYVAEKVGASKIV
LAGGAQAVAAMAYGTETIPKVDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLV
IADEDADVDFVASDLLSQAEHGIDSQVILVGVNLSEKKIQEIQDAVHNQALQLPRVDIVR
KCIAHSTIVLCDGYEEALEMSNQYAPEHLILQIANANDYVKLVDNAGSVFVGAYTPESCG
DYSSGTNHTLPTYGYARQYSGANTATFQKFITAQNITPEGLENIGRAVMCVAKKEGLDGH
RNAVKIRMSKLGLIPKDFQ
NT seq 2400 nt   +upstreamnt  +downstreamnt
atggttttgccgattctaccgttaattgatgatctggcctcatggaatagtaagaaggaa
tacgtttcacttgttggtcaggtacttttggatggctcgagcctgagtaatgaagagatt
ctccagttctccaaagaggaagaagttccattggtggctttgtccttgccaagtggtaaa
ttcagcgatgatgaaatcattgccttcttgaacaacggagtttcttctctgttcattgct
agccaagatgctaaaacagccgaacacttggttgaacaattgaatgtaccaaaggagcgt
gttgttgtggaagagaacggtgttttctccaatcaattcatggtaaaacaaaaattctcg
caagataaaattgtgtccataaagaaattaagcaaggatatgttgaccaaagaagtgctt
ggtgaagtacgtacagaccgtcctgacggtttatataccaccctagttgtcgaccaatat
gagcgttgtctagggttggtgtattcttcgaagaaatctatagcaaaggccatcgatttg
ggtcgtggcgtttattattctcgttctaggaatgaaatctggatcaagggtgaaacttct
ggcaatggccaaaagcttttacaaatctctactgactgtgattcggatgccttaaagttt
atcgttgaacaagaaaacgttggattttgccacttggagaccatgtcttgctttggtgaa
ttcaagcatggtttggtggggctagaatctttactaaaacaaaggctacaggacgctcca
gaggaatcttatactagaagactattcaacgactctgcattgttagatgccaagatcaag
gaagaagctgaagaactgactgaggcaaagggtaagaaggagctttcttgggaggctgcc
gatttgttctactttgcactggccaaattagtggccaacgatgtttcattgaaggacgtc
gagaataatctgaatatgaagcatctgaaggttacaagacggaaaggtgatgctaagcca
aagtttgttggacaaccaaaggctgaagaagaaaaactgaccggtccaattcacttggac
gtggtgaaggcttccgacaaagttggtgtgcagaaggctttgagcagaccaatccaaaag
acttctgaaattatgcatttagtcaatccgatcatcgaaaatgttagagacaaaggtaac
tctgcccttttggagtacacagaaaagtttgatggtgtaaaattatccaatcctgttctt
aatgctccattcccagaagaatactttgaaggtttaaccgaggaaatgaaggaagctttg
gacctttcaattgaaaacgtccgcaaattccatgctgctcaattgccaacagagactctt
gaagttgaaacccaacctggtgtcttgtgttccagattccctcgtcctattgaaaaagtt
ggtttgtatatccctggtggcactgccattttaccaagtactgcattaatgcttggtgtt
ccagcacaagttgcccaatgtaaggagattgtgtttgcatctccaccaagaaaatctgat
ggtaaagtttcacccgaagttgtttatgtcgcagaaaaagttggcgcttccaagattgtt
ctagctggtggtgcccaagccgttgctgctatggcttacgggacagaaactattcctaaa
gtggataagatcttgggtccaggtaatcaatttgtgactgccgccaaaatgtatgttcaa
aatgacactcaagctctatgttccattgatatgccagctggcccaagtgaagttttggtt
attgccgatgaagatgccgatgtggattttgttgcaagtgatttgctatcgcaagctgaa
cacggtattgactcccaagttatccttgttggtgttaacttgagcgaaaagaaaattcaa
gagattcaagatgctgtccacaatcaagctttacaactgccacgtgtggatattgttcgt
aaatgtattgctcacagtacgatcgttctttgtgacggttacgaagaagcccttgaaatg
tccaaccaatatgcaccagaacatttgattctacaaatcgccaatgctaacgattatgtt
aaattggttgacaatgcagggtccgtatttgtgggtgcttacactccagaatcgtgcggt
gactattcaagtggtactaaccatacattaccaacctatggttacgctaggcagtacagt
ggtgccaacactgcaaccttccaaaagtttatcactgcccaaaacattacccctgaaggt
ttagaaaacatcggtagagctgttatgtgcgttgccaagaaggagggtctagacggtcac
agaaacgctgtgaaaatcagaatgagtaagcttgggttgatcccaaaggatttccagtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (8)   
   KEGG ENZYME (3)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (53)   

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