KEGG   Saccharomyces cerevisiae (budding yeast): YDR158W
Entry
YDR158W           CDS       T00005                                 
Symbol
HOM2, THR2
Name
(RefSeq) aspartate-semialdehyde dehydrogenase
  KO
K00133  aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00260  Glycine, serine and threonine metabolism
sce00261  Monobactam biosynthesis
sce00270  Cysteine and methionine metabolism
sce00300  Lysine biosynthesis
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
sce01210  2-Oxocarboxylic acid metabolism
sce01230  Biosynthesis of amino acids
Module
sce_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
sce_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    YDR158W (HOM2)
   00270 Cysteine and methionine metabolism
    YDR158W (HOM2)
   00300 Lysine biosynthesis
    YDR158W (HOM2)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    YDR158W (HOM2)
Enzymes [BR:sce01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.11  aspartate-semialdehyde dehydrogenase
     YDR158W (HOM2)
SSDB
Motif
Pfam: Semialdhyde_dhC Semialdhyde_dh DXP_reductoisom Sacchrp_dh_NADP DapB_N
Other DBs
NCBI-GeneID: 851736
NCBI-ProteinID: NP_010442
SGD: S000002565
UniProt: P13663
Position
IV:770357..771454
AA seq 365 aa
MAGKKIAGVLGATGSVGQRFILLLANHPHFELKVLGASSRSAGKKYVDAVNWKQTDLLPE
SATDIIVSECKSEFFKECDIVFSGLDADYAGAIEKEFMEAGIAIVSNAKNYRREQDVPLI
VPVVNPEHLDIVAQKLDTAKAQGKPRPGFIICISNCSTAGLVAPLKPLIEKFGPIDALTT
TTLQAISGAGFSPGVPGIDILDNIIPYIGGEEDKMEWETKKILAPLAEDKTHVKLLTPEE
IKVSAQCNRVAVSDGHTECISLRFKNRPAPSVEQVKTCLKEYVCDAYKLGCHSAPKQTIH
VLEQPDRPQPRLDRNRDSGYGVSVGRIREDPLLDFKMVVLSHNTIIGAAGSGVLIAEILL
ARNLI
NT seq 1098 nt   +upstreamnt  +downstreamnt
atggctggaaagaaaattgctggtgttttgggtgctactggttccgttggtcaacgtttc
attctgttgttggcaaatcaccctcatttcgaactgaaagttcttggtgcctcttctaga
tcagctggcaagaaatacgttgacgctgtgaactggaagcaaaccgatttgctaccggaa
tctgctaccgatattattgtttccgaatgtaaatctgaattctttaaagagtgtgacatc
gtcttttccggattggatgctgactatgctggcgctatcgaaaaggaattcatggaagct
ggtatcgccattgtttccaatgccaagaattatagaagagaacaagatgtgccattgatt
gttcctgttgtcaatcctgagcatttggatattgtagctcaaaagcttgacaccgccaag
gctcaaggtaagccaagaccagggttcattatctgtatttccaattgttccactgcaggt
ttggttgcaccattgaagcctttgattgaaaaattcggtcctattgatgctttgaccact
actactttgcaagcaatctcaggtgctggtttctccccaggtgtaccaggtattgatatt
ctagacaatattattccatacattggtggtgaagaagacaagatggaatgggagaccaag
aaaatcttggctccattagcagaagacaagacacacgtcaaactattgactccagaagaa
atcaaagtctctgctcaatgtaacagagtcgctgtttccgatgggcacaccgaatgtatc
tctttgaggttcaagaacagacctgctccatccgtcgagcaagtcaagacatgcctaaaa
gaatacgtctgcgatgcctacaaattaggctgtcattctgctccaaagcaaactattcat
gttttggaacaaccagacagacctcaaccaaggttggacaggaacagagacagcggttac
ggtgtttccgttggtagaatcagagaagacccattgttagatttcaaaatggttgtcctt
tcccacaacaccattattggtgccgctggttctggtgtcttgattgccgaaatcttacta
gcaagaaacttgatttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (15)   
   KEGG PATHWAY (8)   
   KEGG MODULE (7)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (48)   

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