KEGG   Saccharomyces cerevisiae (budding yeast): YJR139C
Entry
YJR139C           CDS       T00005                                 
Symbol
HOM6, THR6
Name
(RefSeq) homoserine dehydrogenase
  KO
K00003  homoserine dehydrogenase [EC:1.1.1.3]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00260  Glycine, serine and threonine metabolism
sce00270  Cysteine and methionine metabolism
sce00300  Lysine biosynthesis
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
sce01230  Biosynthesis of amino acids
Module
sce_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
sce_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    YJR139C (HOM6)
   00270 Cysteine and methionine metabolism
    YJR139C (HOM6)
   00300 Lysine biosynthesis
    YJR139C (HOM6)
Enzymes [BR:sce01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     YJR139C (HOM6)
SSDB
Motif
Pfam: Homoserine_dh NAD_binding_3 DUF5101
Other DBs
NCBI-GeneID: 853604
NCBI-ProteinID: NP_012673
SGD: S000003900
UniProt: P31116
Structure
Position
X:complement(689445..690524)
AA seq 359 aa
MSTKVVNVAVIGAGVVGSAFLDQLLAMKSTITYNLVLLAEAERSLISKDFSPLNVGSDWK
AALAASTTKTLPLDDLIAHLKTSPKPVILVDNTSSAYIAGFYTKFVENGISIATPNKKAF
SSDLATWKALFSNKPTNGFVYHEATVGAGLPIISFLREIIQTGDEVEKIEGIFSGTLSYI
FNEFSTSQANDVKFSDVVKVAKKLGYTEPDPRDDLNGLDVARKVTIVGRISGVEVESPTS
FPVQSLIPKPLESVKSADEFLEKLSDYDKDLTQLKKEAATENKVLRFIGKVDVATKSVSV
GIEKYDYSHPFASLKGSDNVISIKTKRYTNPVVIQGAGAGAAVTAAGVLGDVIKIAQRL
NT seq 1080 nt   +upstreamnt  +downstreamnt
atgagcactaaagttgttaatgttgccgttatcggtgccggtgttgttggttcagctttc
ttggatcaattgttagccatgaagtctaccattacttacaatctagttcttttggctgaa
gctgagcgttctttaatctccaaggacttttctccattaaatgttggttctgattggaag
gctgctttagcagcctccactactaaaacgttgcctttggatgatttaattgctcatttg
aagacttcacctaagccagtcattttggttgataacacttccagcgcttacattgctggt
ttttacactaagtttgtcgaaaatggtatttccattgctactccaaacaagaaggccttt
tcctctgatttggctacctggaaggctcttttctcaaataagccaactaacggttttgtc
tatcatgaagctaccgtcggtgctggtttgcctatcatcagtttcttaagagaaattatt
caaaccggtgacgaagttgaaaaaattgaaggtatcttctctggtactctatcttatatt
ttcaacgagttctccactagtcaagctaacgacgtcaaattctctgatgttgtcaaagtt
gctaaaaaattgggttatactgaaccagatccaagagatgatttgaatgggttggatgtt
gctagaaaggttaccattgttggtaggatatctggtgtggaagttgaatctccaacttcc
ttccctgtccagtctttgattccaaaaccattggaatctgtcaagtctgctgatgaattc
ttggaaaaattatctgattacgataaagatttgactcaattgaagaaggaagctgccact
gaaaataaggtattgagattcattggtaaagtcgatgttgccaccaaatctgtgtctgta
ggaattgaaaagtacgattactcacacccattcgcatcattgaagggatcagataacgtt
atttccatcaagactaagcgttacaccaatcctgttgtcattcaaggtgccggtgccggt
gctgccgttactgccgctggtgttttgggtgatgttatcaagattgctcaaagactttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (4)   
   PDB (4)   
Protein domain (3)   
   Pfam (3)   
All databases (44)   

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