KEGG   Saccharomyces cerevisiae (budding yeast): YPL214C
Entry
YPL214C           CDS       T00005                                 
Symbol
THI6
Name
(RefSeq) bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase
  KO
K14154  thiamine-phosphate diphosphorylase / hydroxyethylthiazole kinase [EC:2.5.1.3 2.7.1.50]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00730  Thiamine metabolism
sce01100  Metabolic pathways
sce01240  Biosynthesis of cofactors
Module
sce_M00898  Thiamine biosynthesis, pyridoxal-5P => TMP/thiamine/TPP
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    YPL214C (THI6)
Enzymes [BR:sce01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     YPL214C (THI6)
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.50  hydroxyethylthiazole kinase
     YPL214C (THI6)
SSDB
Motif
Pfam: HK TMP-TENI
Other DBs
NCBI-GeneID: 855887
NCBI-ProteinID: NP_015110
SGD: S000006135
UniProt: P41835
Position
XVI:complement(148569..150191)
AA seq 540 aa
MVFTKEEVDYSLYLVTDSTMLPPGTTLCSQVEAGLKNGVTLVQIREKDIETKNFVAEALE
VQKICKKYNVPLIINDRIDVAMAIDADGVHVGQDDMPIPMVRKLLGPSKILGWSVGKPSE
VETLAKWGPDMVDYIGVGTLFPTSTKKNPKKSPMGPQGAIAILDALEEFKATWCRTVGIG
GLHPDNIQRVLCQCVASNGKRSLDGISLVSDIMAAPDACAATKRLRGLLDATRYQFVECE
LNNTFPTTTSIQNVISQVSNNRPLVQHITNKVHQNFGANVTLALGSSPIMSEIESEVSEL
ARIPNASLLLNTGSVAPIEMLKAAINAYNEVNRPITFDPVGYSATETRLCLNNTLLTYGQ
FACIKGNCSEILSLAKLNNHKMKGVDSSSGKTNIDTLVRATQIVAFQYRTVAVCTGEFDC
VADGTFGGEYKLSSGTEGITAEDLPCVIIEDGPIPIMGDITASGCSLGSTIASFIGGLDS
TGKLFDAVVGAVLLYKSAGKLASTRCQGSGSFHVELIDALYQLFHENKPEKWSASLKKFK
NT seq 1623 nt   +upstreamnt  +downstreamnt
atggtatttactaaggaagaagttgattactcattatatctggttacagattctaccatg
cttccaccgggaactactttatgttctcaggttgaagctgggttgaaaaatggtgtaacg
ctagttcaaatccgtgaaaaggatattgaaacaaaaaatttcgttgcagaggctttagaa
gttcaaaaaatatgtaagaagtacaatgttccacttattatcaatgaccgtatagacgtc
gctatggcaattgacgccgatggggttcatgtgggccaggacgatatgccaatcccaatg
gtaagaaaacttttgggcccttctaaaattcttggatggagtgttggtaaaccttcggag
gtagagacattggctaaatgggggccagatatggtagattatattggtgttggtactctt
ttccctacatcaacaaagaaaaatcctaagaaatcacccatgggtcctcaaggcgccatt
gccattttggatgctttggaggaatttaaagctacatggtgtagaaccgttggtattggt
ggtcttcatcctgacaatattcaacgtgtgctttgtcaatgtgttgcttcaaatggaaag
agatcgttggatggtatctctctagtcagcgatattatggccgctccagatgcatgtgca
gcaaccaagaggttgagaggcttgttagatgctaccagataccaatttgttgagtgcgag
ttaaataatacatttccgaccacaacttcaattcaaaacgttatatctcaagtatcaaac
aatcgtccattagtgcaacatatcaccaataaggttcatcaaaattttggtgccaatgtc
actctagctttaggctcatctcctatcatgtctgaaattgaaagtgaagtatctgaacta
gcaagaatcccaaatgcttctttactgttaaataccggatcagtggcacctattgaaatg
ctaaaagccgcaattaatgcttataatgaagtaaatagacccatcacctttgacccggtc
gggtacagcgccactgaaacaaggctctgtctaaacaacactttgctcacttacggccaa
tttgcttgtataaagggcaattgcagtgaaatactgtctctagccaagttaaataaccat
aaaatgaagggcgtcgactctagcagcggcaaaacgaacatcgacacacttgtgcgcgct
acacaaattgtggcattccaatacaggactgttgctgtttgcacgggtgagtttgattgc
gttgctgatggtacttttggaggcgaatacaaactttcatcaggaacagaaggaataacc
gctgaagatcttccatgtgtaataattgaagatggcccaattcctatcatgggtgacatc
actgcaagtggatgttcacttggttctacaattgcttcctttatcggtgggttagattcc
actggaaaactgtttgatgctgtggttggtgctgtcctattatacaaatcagctggtaag
ttggcttccacccgttgtcaaggaagtggttcattccatgtcgaattgattgacgcatta
tatcaattattccatgaaaataaaccagaaaagtggtccgcttctttgaagaaattcaaa
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (41)   

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