KEGG   Saccharomyces cerevisiae (budding yeast): YER125W
Entry
YER125W           CDS       T00005                                 
Symbol
RSP5, HPG1, MDP1, MUT2, NPI1, SMM1, UBY1
Name
(RefSeq) NEDD4 family E3 ubiquitin-protein ligase
  KO
K10591  E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce04011  MAPK signaling pathway - yeast
sce04120  Ubiquitin mediated proteolysis
sce04144  Endocytosis
Brite
KEGG Orthology (KO) [BR:sce00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    YER125W (RSP5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04011 MAPK signaling pathway - yeast
    YER125W (RSP5)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    YER125W (RSP5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sce04131]
    YER125W (RSP5)
   04121 Ubiquitin system [BR:sce04121]
    YER125W (RSP5)
   03029 Mitochondrial biogenesis [BR:sce03029]
    YER125W (RSP5)
Enzymes [BR:sce01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     YER125W (RSP5)
Membrane trafficking [BR:sce04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    YER125W (RSP5)
Ubiquitin system [BR:sce04121]
 Ubiquitin ligases (E3)
  HECT type E3
   YER125W (RSP5)
Mitochondrial biogenesis [BR:sce03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Morphogenesis factors
    YER125W (RSP5)
SSDB
Motif
Pfam: HECT WW C2
Other DBs
NCBI-GeneID: 856862
NCBI-ProteinID: NP_011051
SGD: S000000927
UniProt: P39940
Structure
Position
V:410189..412618
AA seq 809 aa
MPSSISVKLVAAESLYKRDVFRSPDPFAVLTIDGYQTKSTSAAKKTLNPYWNETFKFDDI
NENSILTIQVFDQKKFKKKDQGFLGVVNVRVGDVLGHLDEDTATSSGRPREETITRDLKK
SNDGMAVSGRLIVVLSKLPSSSPHSQAPSGHTASSSTNTSSTTRTNGHSTSSTRNHSTSH
PSRGTAQAVESTLQSGTTAATNTATTSHRSTNSTSSATRQYSSFEDQYGRLPPGWERRTD
NFGRTYYVDHNTRTTTWKRPTLDQTEAERGNQLNANTELERRQHRGRTLPGGSSDNSSVT
VQVGGGSNIPPVNGAAAAAFAATGGTTSGLGELPSGWEQRFTPEGRAYFVDHNTRTTTWV
DPRRQQYIRTYGPTNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRL
PSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIKVRRKNIFEDAYQEIMRQTPEDL
KKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAYDNYTIQINPNSGINPE
HLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWMLE
NSIDGVLDLTFSADDERFGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQF
KAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIEDWKKHTDYRGYQESDEVIQWFWK
CVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNR
VDLPQYVDYDSMKQKLTLAVEETIGFGQE
NT seq 2430 nt   +upstreamnt  +downstreamnt
atgccttcatccatatccgtcaagttagtggctgcagagtcattatataagagggacgta
ttccgttccccggatccgtttgctgttctgactattgatggttaccaaaccaaatctaca
tccgcagcgaagaaaacgttaaatccctactggaatgagactttcaaattcgacgatatc
aatgaaaattctattttaaccatccaagtctttgatcaaaagaaatttaaaaagaaggat
caagggtttcttggcgtggttaacgtccgcgtgggtgatgttttgggccatttggatgaa
gatactgctacatcgagtggtagacctcgcgaagaaactattactcgtgatttaaaaaaa
tctaatgacggaatggccgtcagcggtaggttgattgttgttttatcaaaactaccttcg
tcaagtccgcattcacaagctccttctggccatactgcatcttctagtacgaatacaagt
tcaactactcgaacaaatggtcattctacttcctccacccgtaatcattcaacgtctcat
ccttccagaggcaccgcgcaagcagtagaatcaactcttcaaagcggtacaacagctgct
actaatacggcaacaaccagtcaccgttccaccaattccacatccagtgctaccagacaa
tactcttcgtttgaagaccagtatggtcgtttaccccctggttgggagagaaggaccgat
aactttggtcgtacatattacgtcgatcataacacaaggactaccacttggaaacgtcca
acgctcgatcaaacagaagccgaacgtggcaaccaattaaatgcaaatactgagttagag
agaaggcagcataggggaagaactttacctggtggatcatcagataattcctctgtaaca
gttcaagtgggaggtggttccaatatacctcctgttaatggtgcagcagcagcagcgttt
gcagctacaggtggtaccacatctggtttaggcgaattaccttcaggctgggagcagcga
tttactccagaaggaagagcttatttcgttgaccataatactagaacaaccacttgggtg
gatccaaggagacaacagtatatacgtacttatggccctacaaataccaccattcagcaa
caaccggtctcccaattaggtcctttgccttctggatgggaaatgagattgaccaatacg
gcacgtgtatatttcgttgaccacaatacaaaaacaacgacctgggatgacccaagactt
ccatcatcgctagaccaaaatgttccacaatacaagcgtgacttcagacgtaaggttatt
tatttcaggtcccagcccgctcttagaatattgccgggacaatgtcatattaaagtacgt
agaaagaacatttttgaggatgcttatcaagaaattatgagacaaaccccagaagattta
aagaaaagattaatgatcaagtttgatggtgaggaaggtttagattacggtggtgtttcc
agagaatttttctttttattatcacatgagatgtttaatccattttattgtttgtttgaa
tattctgcgtatgacaactataccattcaaataaatcctaacagtggcatcaaccccgaa
catttgaactatttcaaattcattggtagagttgtgggtcttggtgttttccatagaaga
tttttggatgcattctttgtaggtgcactttacaaaatgatgctacgtaaaaaagtcgta
ttgcaagatatggaaggtgttgacgcagaggtgtataactcattaaactggatgcttgag
aatagtatagatggtgtcttggatctgacgttcagtgccgacgatgaaagattcggtgaa
gttgtaacagtggatttgaagccagatgggagaaatattgaagttactgatggtaataag
aaagaatatgtcgaattatatacccaatggagaattgttgatagagttcaagaacaattt
aaggcattcatggatggttttaacgaattaatccccgaagacttagtaactgtgtttgat
gagcgtgaactagaactattgatcggtggtattgcggaaattgacattgaagattggaag
aaacacactgattatcgtggttaccaagagtcagacgaggtcattcaatggttttggaag
tgtgtcagtgaatgggataatgaacaaagagcccgtttattgcagttcaccactggtact
tctcgtatacctgtcaacgggtttaaagatttgcaaggctctgatggtccaagaagattc
actattgaaaaagctggtgaagtacaacaattgccaaaatctcacacatgttttaacaga
gttgatttgccacaatacgttgattatgacagcatgaaacagaagctaacattggccgtg
gaagaaaccatagggtttggtcaagaatga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (372)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (53)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   PROTHERM (314)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (392)   

Download RDF
DBGET integrated database retrieval system