KEGG   Streptomyces coelicolor: SCO2088
Entry
SCO2088           CDS       T00085                                 
Symbol
murF, SC4A10.21c
Name
(RefSeq) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-alanyl ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
sco  Streptomyces coelicolor
Pathway
sco00300  Lysine biosynthesis
sco00550  Peptidoglycan biosynthesis
sco01100  Metabolic pathways
sco01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:sco00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    SCO2088 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    SCO2088 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    SCO2088 (murF)
Enzymes [BR:sco01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     SCO2088 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase DUF561
Other DBs
NCBI-GeneID: 1097522
Kitasato: SCO2088
Position
complement(2241793..2243208)
AA seq 471 aa
MITLSLAEIAEVVGGRMHDIPDASAEVTGPVVRDSREAGPGSLFVAFVGERADGHDFAAR
VVEAGAVAVLGSRPVGVPAIVVDDVQAALGALARHVVRRLGTTLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSMNNEVGLPLTALTATDETKFLVLEMGARGIGHIRYLTELTPPKI
GAVLNVGSAHIGEFGGREQIAQAKGELVEALPPAEEGGAAILNADDPLVRAMASRTKAKV
ILFGESGEADVRAENVRLTDTGQPSFSLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSADEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESTKAALRALVAMGKGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREARWLQLGAYNEGSWGEESV
HVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVATALLETGAEGEVAAR
NT seq 1416 nt   +upstreamnt  +downstreamnt
gtgatcaccctctcactcgccgagatcgcagaagtcgtcggcgggcggatgcacgacata
ccggacgcgtccgccgaggtcaccgggccggtcgtccgggactcccgggaagccgggccc
ggcagcctcttcgtcgccttcgtgggcgaacgggccgacggccacgacttcgccgcgcgg
gtcgtcgaagcgggtgcggtggccgtcctcggctcccgtcccgtcggcgtgccggcgatc
gtcgtggacgacgtccaggccgccctgggcgccctcgcccggcacgtcgtgcgacgcctc
ggcaccaccctcgtggccctcaccgggtcggccggcaagaccagcaccaaggacctgatc
gcccaggtactgcgccgcaaggcgcccacggtcttcacgcccggttccatgaacaacgag
gtggggctgccgctcaccgcgctcaccgccaccgacgagacgaagttcctcgtcctggag
atgggcgcccgcggcatcggccacatccggtacctcaccgaactcaccccgccgaagatc
ggcgcggtcctcaacgtcggctccgcgcacatcggcgagttcggcggccgggagcagatc
gcccaggccaagggcgaactcgtcgaggccctgccgccggccgaggagggcggcgccgcg
atcctcaacgcggacgacccgctcgtacgggccatggcctcccgaacgaaggcgaaggtg
atccttttcggagagtccggcgaagcggacgttcgcgccgagaacgtgcgactcacggac
accggacagccttccttcagccttcacacaccctccggtgcaagcgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttg
ggcatgtccgcagacgagatcgccaccgcgctctccgaggcgggctccctctcccgctgg
cggatggaggtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtccaccaaggccgcgctgcgtgcgctggtcgccatgggcaaggggcgtcgt
acgtgggcggtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgac
gcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcgggggcagg
gaagcccgatggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggcggtcgacctgttgcgcagcgagttgcgcccaggagac
gtcgtgctcgtgaaggcgtcccgttcggtgggtctggagagcgtcgccacggcgctcctc
gagaccggcgccgagggtgaggttgccgcccgatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-Gene (1)   
   KITASATO (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (33)   

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