KEGG T00085: SCO4814

Streptomyces coelicolor: SCO4814

Entry

SCO4814           CDS       T00085

Symbol

purH

Name

(RefSeq) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

K00602

phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]

Organism

sco Streptomyces coelicolor

Pathway

sco00230

Purine metabolism

sco00670

One carbon pool by folate

sco01100

Metabolic pathways

sco01110

Biosynthesis of secondary metabolites

Module

sco_M00048

De novo purine biosynthesis, PRPP + glutamine => IMP

Brite

KEGG Orthology (KO) [BR:sco00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    SCO4814 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SCO4814 (purH)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sco04147]
    SCO4814 (purH)
Enzymes [BR:sco01000]
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     SCO4814 (purH)
3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     SCO4814 (purH)
Exosome [BR:sco04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   SCO4814 (purH)

SSDB

Motif

Pfam:

AICARFT_IMPCHas MGS

Other DBs

NCBI-GeneID:

1100255

Kitasato:

SCO4814

Position

5241975..5243546

AA seq 523 aa
MTATAGSNKRAIRRALVSVYDKTGLEDLARGLHEAGVELVSTGSTAGRIAAAGVPVTKVE
ELTGFPECLDGRVKTLHPKVHAGILADLRLESHRQQLDELGVAPFDLVVVNLYPFRETVA
SGATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTSPARYADVLLAVEGGGFDLAARKRLA
AEAFQHTAAYDVAVASWFAAEYAPVDESGFPDFLGATYERANTLRYGENPHQPAALYTSP
EGGGLAQAEQLHGKEMSYNNYTDTDAARRAAYDHAEPCVAIIKHANPCGIAIGADVAEAH
RKAHDCDPVSAYGGVIAVNRPVSKEMAERVAGIFTEVIVAPDYEDGALEALTKKKNIRVL
RAPAAPAAPVEVKPIDGGALLQVTDRLQAEGDDPATWTLATGEALSEAELAELAFAWRAC
RAVKSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAGAERAQGAYAASDAFFPFPDGLE
ILTGAGVKAVVQPGGSVRDELVVEAAKKAGVTMYFTGTRHFFH

NT seq 1572 nt +upstreamnt +downstreamnt
gtgaccgccaccgccggaagcaacaagcgggccatccgtcgcgcactcgtcagcgtctac
gacaagaccgggctcgaggacctcgcccgcgggctgcacgaggccggcgtcgaactcgtc
tccaccgggtccaccgccgggcggatcgccgcggccggcgtccccgtcaccaaggtcgag
gagctgaccgggttccccgagtgcctggacggccgcgtcaagaccctgcaccccaaggtc
cacgcgggcatcctcgccgacctgcgcctggagagccaccggcagcagctcgacgagctg
ggcgtggccccgttcgacctggtcgtggtgaacctctacccgttccgcgagaccgtcgcc
tcgggcgccaccccggacgagtgcgtcgagcagatcgacatcggcggcccctccatggtg
cgcgccgccgccaagaaccacccctccgtcgcggtcgtcaccagccccgcccggtacgcc
gacgtgctcttggcggtcgagggcggcggcttcgacctggccgcccgcaagcgcctggcc
gccgaggccttccagcacaccgccgcctacgacgtggccgtcgcctcctggttcgccgcc
gagtacgccccggtcgacgagtccggcttcccggacttcctcggcgccacctacgagcgc
gccaacaccctgcgctacggcgagaacccgcaccagccggccgcgctctacacctccccc
gaggggggtggcctcgcacaggccgagcagctgcacggcaaggagatgtcgtacaacaac
tacacggacacggacgccgcccgccgtgccgcgtacgaccacgccgagccctgcgtcgcg
atcatcaagcacgccaacccgtgcggcatcgcgatcggcgcggacgtcgccgaggcgcac
cgcaaggcgcacgactgcgacccggtctccgcgtacggcggtgtgatcgcggtcaaccgc
ccggtctccaaggagatggccgagcgggtcgccgggatcttcaccgaggtcatcgtcgcg
ccggactacgaggacggcgcgctcgaagccctcaccaagaagaagaacatccgcgtcctg
cgcgccccggctgcccccgccgccccggtcgaggtcaagccgatcgacggcggtgccctc
ctccaggtcaccgaccgcctccaggccgagggcgacgaccccgccacctggaccctcgcg
accggcgaggcgctgtccgaggcggagctggccgagctggccttcgcctggagggcctgc
cgggccgtcaagtccaacgccatcctcctcgccaaggacggcgcctccgtcggcgtcggc
atgggccaggtcaaccgcgtcgactccgcgaagctcgcggtggagcgcgccggcgccgag
cgggcgcagggcgcctacgcggcctccgacgccttcttccccttcccggacggcctggag
atcctcaccggggccggtgtgaaggccgtggtccagcccggcggctcggtccgcgacgag
ctggtcgtcgaggcggcgaagaaggccggcgtcacgatgtacttcacggggacgcggcac
ttcttccactga

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