KEGG   Streptomyces coelicolor: SCO5087
Entry
SCO5087           CDS       T00085                                 
Symbol
actIORF1, SCBAC28G1.13
Name
(RefSeq) actinorhodin polyketide beta-ketoacyl synthase subunit alpha
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
sco  Streptomyces coelicolor
Pathway
sco00253  Tetracycline biosynthesis
sco01056  Biosynthesis of type II polyketide backbone
sco01100  Metabolic pathways
sco01110  Biosynthesis of secondary metabolites
Module
sco_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:sco00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    SCO5087 (actIORF1)
   00253 Tetracycline biosynthesis
    SCO5087 (actIORF1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:sco01004]
    SCO5087 (actIORF1)
   01008 Polyketide biosynthesis proteins [BR:sco01008]
    SCO5087 (actIORF1)
Enzymes [BR:sco01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     SCO5087 (actIORF1)
    2.3.1.260  tetracycline polyketide synthase
     SCO5087 (actIORF1)
Lipid biosynthesis proteins [BR:sco01004]
 Polyketide synthase
  Component type
   SCO5087 (actIORF1)
Polyketide biosynthesis proteins [BR:sco01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     SCO5087 (actIORF1)
    Nonaketide PKS
     SCO5087 (actIORF1)
    Decaketide PKS
     SCO5087 (actIORF1)
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_N
Other DBs
NCBI-GeneID: 1100528
Kitasato: SCO5087
Position
5529801..5531204
AA seq 467 aa
MPLDAAPVDPASRGPVSAFEPPSSHGADDDDDHRTNASKELFGLKRRVVITGVGVRAPGG
NGTRQFWELLTSGRTATRRISFFDPSPYRSQVAAEADFDPVAEGFGPRELDRMDRASQFA
VACAREAFAASGLDPDTLDPARVGVSLGSAVAAATSLEREYLLLSDSGRDWEVDAAWLSR
HMFDYLVPSVMPAEVAWAVGAEGPVTMVSTGCTSGLDSVGNAVRAIEEGSADVMFAGAAD
TPITPIVVACFDAIRATTARNDDPEHASRPFDGTRDGFVLAEGAAMFVLEDYDSALARGA
RIHAEISGYATRCNAYHMTGLKADGREMAETIRVALDESRTDATDIDYINAHGSGTRQND
RHETAAYKRALGEHARRTPVSSIKSMVGHSLGAIGSLEIAACVLALEHGVVPPTANLRTS
DPECDLDYVPLEARERKLRSVLTVGSGFGGFQSAMVLRDAETAGAAA
NT seq 1404 nt   +upstreamnt  +downstreamnt
gtgccgctggacgcggcgccggtggatccggcatcgaggggtcccgtatcggccttcgag
cctccttcgagccacggggccgacgatgacgacgaccaccggacgaacgcatcgaaggag
ctgttcggattgaagcgcagagtcgtcatcacgggcgtcggcgtccgcgcccccggcggg
aacggcacccggcagttctgggaactgctcacctcggggcggacggcgacgcgccggatc
tcgttcttcgacccctcgccctaccgttcacaggtcgcggcggaggccgacttcgacccg
gtcgccgagggcttcggcccgcgggagctcgaccggatggaccgggcctcgcagttcgcc
gtggcctgtgcccgggaggcgttcgccgccagcgggctcgacccggacaccctcgacccc
gcccgggtcggggtcagcctcggcagcgcggtggcagcggcgaccagcctggagcgcgag
tatctgctgctgtcggactccggccgtgactgggaggtcgacgcggcctggctgtcccgg
cacatgttcgactacctggtgcccagcgtcatgccggccgaggtcgcctgggcggtcggc
gccgagggcccggtcacgatggtctccaccggctgcacctcgggcctggactccgtcggc
aacgcggtccgggcgatcgaggagggcagcgccgacgtgatgttcgcgggagccgccgac
accccgatcaccccgatcgtcgtcgcctgcttcgacgcgatccgcgccacgacggcgcgc
aacgacgacccggagcacgcctcgcggccgttcgacggtacgcgggacggcttcgtgctg
gccgaaggagccgcgatgttcgtcctggaggactacgacagcgcgctggcccgcggagcc
cgcatccacgccgagatctcggggtacgcgacgcgctgcaacgcgtaccacatgacgggc
ctgaaggccgacggccgcgagatggccgagaccatccgggtcgccctcgacgagtcccgc
acggacgcgacggacatcgactacatcaacgcgcacggctccggcacccggcagaacgac
cgccacgagacagcggcgtacaagcgcgccctcggcgaacacgcccggcgcactccggtc
agctcgatcaagtcgatggtcggccactcgctgggcgcgatcggctcgctggagatcgcg
gcctgcgtactcgccctcgaacacggcgtggtgcccccgaccgccaacctgcgcaccagc
gaccccgagtgcgatctcgactacgttccgctggaggccagggagcggaagctgcggtcc
gtactcaccgtgggcagcggcttcggcggcttccagagcgcgatggtgctgcgcgacgcc
gagaccgcgggggcggccgcatga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (12)   
   KEGG ENZYME (2)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-Gene (1)   
   KITASATO (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (53)   

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