KEGG   Streptomyces coelicolor: SCO5553
Entry
SCO5553           CDS       T00085                                 
Symbol
leuC
Name
(RefSeq) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
sco  Streptomyces coelicolor
Pathway
sco00290  Valine, leucine and isoleucine biosynthesis
sco00660  C5-Branched dibasic acid metabolism
sco01100  Metabolic pathways
sco01110  Biosynthesis of secondary metabolites
sco01210  2-Oxocarboxylic acid metabolism
sco01230  Biosynthesis of amino acids
Module
sco_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sco00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    SCO5553 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SCO5553 (leuC)
Enzymes [BR:sco01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     SCO5553 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     SCO5553 (leuC)
SSDB
Motif
Pfam: Aconitase DUF4946
Other DBs
NCBI-GeneID: 1100993
Kitasato: SCO5553
Position
6052013..6053443
AA seq 476 aa
MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPEGVTA
KDLILAIIARIGTGGGQGYILEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLQGRPHAPEGADWDAAVEYWKTLRTDDDAEFDAEVVIEAAELAPFVTWGTNPGQGAPL
SAAVPDPASYEDASERFAAEKALEYMGLEAGQPLRSIQVDTVFVGSCTNGRIEDLRAAAE
IVRDRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSAADVPTPAGV
NT seq 1431 nt   +upstreamnt  +downstreamnt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgcaagagcggccgcccggtgcggcggctcgacctgaccatcgccacc
gaggaccacaacacccccacgctcgacatcgacaagcccatcgcggacccggtctcccgg
gcccagctggagacgctgcgcaagaactgcgcggacttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtcggcccgcagctcggtctgacccagccc
ggcaccaccgtggtctgcggcgactcgcacacctcgacgcacggcgccttcggcgcgctc
gcgttcggcatcggcacctcccaggtcgagcacgtgctggccacccagacgctgcccctg
gcccgcccgaagaccatggcgatcacggtcgacggcgagctgcccgagggtgtcaccgcc
aaggacctgatcctggcgatcatcgcgcggatcggcaccggcggcggccagggctacatc
ctggagtaccgcggcgaggccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcctacctccagggccgcccgcacgcccccgagggcgccgactgggacgcggcggtggag
tactggaagacgctgcgtacggacgacgacgccgagttcgacgccgaggtggtcatcgag
gccgccgagctggcgccgttcgtcacctggggcaccaaccctggccagggcgcaccgctt
tccgcggccgtccccgacccggcttcgtacgaggacgcctcggagcgcttcgccgccgaa
aaggccctggagtacatgggcttggaggccgggcagccgctgcgctccatccaggtggac
accgtcttcgtgggctcctgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
atcgtccgggaccgcaaagtcgccgacggcgtacgcatgctggtcgtccccggctccgcg
cgggtcggtctgcaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaacccggaccagctggccccg
ggtgagcgctccgcgtccacctccaaccgcaacttcgaggggcgccagggcaagggcggc
cgcacccacctggtgtcgccgcaggtcgcggccgcgacggcggtcctgggccacctggcc
tccccggccgacctgtccgccgccgacgtccccacgcccgctggagtctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-Gene (1)   
   KITASATO (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (50)   

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