KEGG   Sus scrofa (pig): 100127478
Entry
100127478         CDS       T01009                                 
Symbol
AKT2
Name
(RefSeq) RAC-beta serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc01521  EGFR tyrosine kinase inhibitor resistance
ssc01522  Endocrine resistance
ssc01524  Platinum drug resistance
ssc04010  MAPK signaling pathway
ssc04012  ErbB signaling pathway
ssc04014  Ras signaling pathway
ssc04015  Rap1 signaling pathway
ssc04022  cGMP-PKG signaling pathway
ssc04024  cAMP signaling pathway
ssc04062  Chemokine signaling pathway
ssc04066  HIF-1 signaling pathway
ssc04068  FoxO signaling pathway
ssc04071  Sphingolipid signaling pathway
ssc04072  Phospholipase D signaling pathway
ssc04140  Autophagy - animal
ssc04150  mTOR signaling pathway
ssc04151  PI3K-Akt signaling pathway
ssc04152  AMPK signaling pathway
ssc04210  Apoptosis
ssc04211  Longevity regulating pathway
ssc04213  Longevity regulating pathway - multiple species
ssc04218  Cellular senescence
ssc04261  Adrenergic signaling in cardiomyocytes
ssc04370  VEGF signaling pathway
ssc04371  Apelin signaling pathway
ssc04380  Osteoclast differentiation
ssc04510  Focal adhesion
ssc04550  Signaling pathways regulating pluripotency of stem cells
ssc04611  Platelet activation
ssc04613  Neutrophil extracellular trap formation
ssc04620  Toll-like receptor signaling pathway
ssc04625  C-type lectin receptor signaling pathway
ssc04630  JAK-STAT signaling pathway
ssc04660  T cell receptor signaling pathway
ssc04662  B cell receptor signaling pathway
ssc04664  Fc epsilon RI signaling pathway
ssc04666  Fc gamma R-mediated phagocytosis
ssc04668  TNF signaling pathway
ssc04722  Neurotrophin signaling pathway
ssc04725  Cholinergic synapse
ssc04728  Dopaminergic synapse
ssc04810  Regulation of actin cytoskeleton
ssc04910  Insulin signaling pathway
ssc04914  Progesterone-mediated oocyte maturation
ssc04915  Estrogen signaling pathway
ssc04917  Prolactin signaling pathway
ssc04919  Thyroid hormone signaling pathway
ssc04920  Adipocytokine signaling pathway
ssc04922  Glucagon signaling pathway
ssc04923  Regulation of lipolysis in adipocytes
ssc04926  Relaxin signaling pathway
ssc04929  GnRH secretion
ssc04931  Insulin resistance
ssc04932  Non-alcoholic fatty liver disease
ssc04933  AGE-RAGE signaling pathway in diabetic complications
ssc04935  Growth hormone synthesis, secretion and action
ssc04936  Alcoholic liver disease
ssc04973  Carbohydrate digestion and absorption
ssc05010  Alzheimer disease
ssc05017  Spinocerebellar ataxia
ssc05132  Salmonella infection
ssc05135  Yersinia infection
ssc05142  Chagas disease
ssc05145  Toxoplasmosis
ssc05152  Tuberculosis
ssc05160  Hepatitis C
ssc05161  Hepatitis B
ssc05162  Measles
ssc05163  Human cytomegalovirus infection
ssc05164  Influenza A
ssc05165  Human papillomavirus infection
ssc05166  Human T-cell leukemia virus 1 infection
ssc05167  Kaposi sarcoma-associated herpesvirus infection
ssc05168  Herpes simplex virus 1 infection
ssc05169  Epstein-Barr virus infection
ssc05170  Human immunodeficiency virus 1 infection
ssc05200  Pathways in cancer
ssc05205  Proteoglycans in cancer
ssc05207  Chemical carcinogenesis - receptor activation
ssc05208  Chemical carcinogenesis - reactive oxygen species
ssc05210  Colorectal cancer
ssc05211  Renal cell carcinoma
ssc05212  Pancreatic cancer
ssc05213  Endometrial cancer
ssc05214  Glioma
ssc05215  Prostate cancer
ssc05218  Melanoma
ssc05220  Chronic myeloid leukemia
ssc05221  Acute myeloid leukemia
ssc05222  Small cell lung cancer
ssc05223  Non-small cell lung cancer
ssc05224  Breast cancer
ssc05225  Hepatocellular carcinoma
ssc05226  Gastric cancer
ssc05230  Central carbon metabolism in cancer
ssc05231  Choline metabolism in cancer
ssc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ssc05415  Diabetic cardiomyopathy
ssc05417  Lipid and atherosclerosis
ssc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100127478 (AKT2)
   04012 ErbB signaling pathway
    100127478 (AKT2)
   04014 Ras signaling pathway
    100127478 (AKT2)
   04015 Rap1 signaling pathway
    100127478 (AKT2)
   04370 VEGF signaling pathway
    100127478 (AKT2)
   04371 Apelin signaling pathway
    100127478 (AKT2)
   04630 JAK-STAT signaling pathway
    100127478 (AKT2)
   04668 TNF signaling pathway
    100127478 (AKT2)
   04066 HIF-1 signaling pathway
    100127478 (AKT2)
   04068 FoxO signaling pathway
    100127478 (AKT2)
   04072 Phospholipase D signaling pathway
    100127478 (AKT2)
   04071 Sphingolipid signaling pathway
    100127478 (AKT2)
   04024 cAMP signaling pathway
    100127478 (AKT2)
   04022 cGMP-PKG signaling pathway
    100127478 (AKT2)
   04151 PI3K-Akt signaling pathway
    100127478 (AKT2)
   04152 AMPK signaling pathway
    100127478 (AKT2)
   04150 mTOR signaling pathway
    100127478 (AKT2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100127478 (AKT2)
  09143 Cell growth and death
   04210 Apoptosis
    100127478 (AKT2)
   04218 Cellular senescence
    100127478 (AKT2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100127478 (AKT2)
   04550 Signaling pathways regulating pluripotency of stem cells
    100127478 (AKT2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100127478 (AKT2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100127478 (AKT2)
   04613 Neutrophil extracellular trap formation
    100127478 (AKT2)
   04620 Toll-like receptor signaling pathway
    100127478 (AKT2)
   04625 C-type lectin receptor signaling pathway
    100127478 (AKT2)
   04660 T cell receptor signaling pathway
    100127478 (AKT2)
   04662 B cell receptor signaling pathway
    100127478 (AKT2)
   04664 Fc epsilon RI signaling pathway
    100127478 (AKT2)
   04666 Fc gamma R-mediated phagocytosis
    100127478 (AKT2)
   04062 Chemokine signaling pathway
    100127478 (AKT2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100127478 (AKT2)
   04922 Glucagon signaling pathway
    100127478 (AKT2)
   04923 Regulation of lipolysis in adipocytes
    100127478 (AKT2)
   04920 Adipocytokine signaling pathway
    100127478 (AKT2)
   04929 GnRH secretion
    100127478 (AKT2)
   04915 Estrogen signaling pathway
    100127478 (AKT2)
   04914 Progesterone-mediated oocyte maturation
    100127478 (AKT2)
   04917 Prolactin signaling pathway
    100127478 (AKT2)
   04926 Relaxin signaling pathway
    100127478 (AKT2)
   04935 Growth hormone synthesis, secretion and action
    100127478 (AKT2)
   04919 Thyroid hormone signaling pathway
    100127478 (AKT2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100127478 (AKT2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    100127478 (AKT2)
  09156 Nervous system
   04725 Cholinergic synapse
    100127478 (AKT2)
   04728 Dopaminergic synapse
    100127478 (AKT2)
   04722 Neurotrophin signaling pathway
    100127478 (AKT2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100127478 (AKT2)
  09149 Aging
   04211 Longevity regulating pathway
    100127478 (AKT2)
   04213 Longevity regulating pathway - multiple species
    100127478 (AKT2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100127478 (AKT2)
   05205 Proteoglycans in cancer
    100127478 (AKT2)
   05207 Chemical carcinogenesis - receptor activation
    100127478 (AKT2)
   05208 Chemical carcinogenesis - reactive oxygen species
    100127478 (AKT2)
   05230 Central carbon metabolism in cancer
    100127478 (AKT2)
   05231 Choline metabolism in cancer
    100127478 (AKT2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100127478 (AKT2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100127478 (AKT2)
   05212 Pancreatic cancer
    100127478 (AKT2)
   05225 Hepatocellular carcinoma
    100127478 (AKT2)
   05226 Gastric cancer
    100127478 (AKT2)
   05214 Glioma
    100127478 (AKT2)
   05221 Acute myeloid leukemia
    100127478 (AKT2)
   05220 Chronic myeloid leukemia
    100127478 (AKT2)
   05218 Melanoma
    100127478 (AKT2)
   05211 Renal cell carcinoma
    100127478 (AKT2)
   05215 Prostate cancer
    100127478 (AKT2)
   05213 Endometrial cancer
    100127478 (AKT2)
   05224 Breast cancer
    100127478 (AKT2)
   05222 Small cell lung cancer
    100127478 (AKT2)
   05223 Non-small cell lung cancer
    100127478 (AKT2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100127478 (AKT2)
   05170 Human immunodeficiency virus 1 infection
    100127478 (AKT2)
   05161 Hepatitis B
    100127478 (AKT2)
   05160 Hepatitis C
    100127478 (AKT2)
   05164 Influenza A
    100127478 (AKT2)
   05162 Measles
    100127478 (AKT2)
   05168 Herpes simplex virus 1 infection
    100127478 (AKT2)
   05163 Human cytomegalovirus infection
    100127478 (AKT2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100127478 (AKT2)
   05169 Epstein-Barr virus infection
    100127478 (AKT2)
   05165 Human papillomavirus infection
    100127478 (AKT2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100127478 (AKT2)
   05135 Yersinia infection
    100127478 (AKT2)
   05152 Tuberculosis
    100127478 (AKT2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100127478 (AKT2)
   05142 Chagas disease
    100127478 (AKT2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100127478 (AKT2)
   05017 Spinocerebellar ataxia
    100127478 (AKT2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100127478 (AKT2)
   05418 Fluid shear stress and atherosclerosis
    100127478 (AKT2)
   05415 Diabetic cardiomyopathy
    100127478 (AKT2)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100127478 (AKT2)
   04932 Non-alcoholic fatty liver disease
    100127478 (AKT2)
   04931 Insulin resistance
    100127478 (AKT2)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100127478 (AKT2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100127478 (AKT2)
   01524 Platinum drug resistance
    100127478 (AKT2)
   01522 Endocrine resistance
    100127478 (AKT2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ssc01001]
    100127478 (AKT2)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100127478 (AKT2)
Protein kinases [BR:ssc01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   100127478 (AKT2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Kinase-like Pkinase_C PH_20 PH_11 ABC1
Other DBs
NCBI-GeneID: 100127478
NCBI-ProteinID: NP_001243708
Ensembl: ENSSSCG00000002989
Vega: OTTSUSG00000002304
UniProt: G9BWQ2 A0A8D0Y1T1
Position
6:complement(48555785..48620472)
AA seq 481 aa
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGAGEDPM
DYKCGSPSDSSAAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLTVNWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgaatgaggtgtctgtcatcaaagaaggctggctccacaagcgtggtgaatacatcaag
acctggaggccccggtacttcctgctgaagagtgacggctccttcattggctataaggag
cggcccgaggcccccgaccagaccctgccccccttaaacaacttctccgtagcagaatgc
cagctgatgaagaccgagagacctcggcccaacacctttgtcatacgctgcctgcagtgg
accacagtcatcgagaggaccttccatgtggactccccggatgagagggaggagtggatg
cgggccatccagatggttgccaacagcctcaagcagcggggcgcaggtgaggaccccatg
gactacaagtgtggctcccccagtgactcctctgctgctgaggagatggaagtggcagtg
agcaaggctcgggccaaggtgaccatgaacgacttcgactatctcaagctcctgggcaag
ggcacgttcggcaaagtcatcctggtgcgcgagaaggccaccggccgctactacgccatg
aagatcctgcggaaggaggttatcatcgccaaggatgaagtcgcccacacggtcaccgag
agccgggttctccagaacaccaggcacccgttcctcaccgcgctgaagtacgccttccag
acccacgaccgcctgtgcttcgtgatggagtacgccaacggtggcgagctgtttttccac
ctgtcccgggagcgcgtcttcacggaggagcgggcccgtttctacggcgcggagattgtc
tcggctctggagtacctgcactcgagggacgtggtgtaccgcgacatcaagctggaaaac
ctcatgctggacaaagacggccacatcaagatcacggacttcggcctgtgcaaagagggc
atcagtgatggggccaccatgaaaaccttctgtgggacccccgaatacctggcacccgag
gtgctggaggacaacgactacggccgggccgtggactggtgggggctgggcgtggtcatg
tacgagatgatgtgcggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag
ctcatcctcatggaggagatccgcttcccgcgcacgctcagccccgaggccaagtccttg
cttgcggggctgcttaagaaggacccaaagcagaggctcggcggggggcccagcgatgcc
aaggaggtcatggagcacaggttcttcctcaccgtcaactggcaggacgtggtacagaag
aagctcctgccacccttcaaacctcaggtcacatctgaggtcgacactcggtactttgac
gatgaattcaccgcccaatccatcacaatcacgcccccggaccgctatgacagcctgggc
tcgctcgaactggaccagcggacccacttcccccagttctcctactcggccagcatccgg
gagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (100)   
   KEGG PATHWAY (100)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (12)   
   UniProt (2)   
   RefSeq(pep) (10)   
DNA sequence (17)   
   RefSeq(nuc) (11)   
   GenBank (3)   
   EMBL (3)   
Protein domain (8)   
   Pfam (8)   
All databases (151)   

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