KEGG   Sus scrofa (pig): 100155309
Entry
100155309         CDS       T01009                                 
Symbol
IDE
Name
(RefSeq) insulin-degrading enzyme isoform X1
  KO
K01408  insulysin [EC:3.4.24.56]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc03266  Virion - Herpesvirus
ssc05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03266 Virion - Herpesvirus
    100155309 (IDE)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100155309 (IDE)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ssc01002]
    100155309 (IDE)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.56  insulysin
     100155309 (IDE)
Peptidases and inhibitors [BR:ssc01002]
 Metallo peptidases
  Family M16: pitrilysin family
   100155309 (IDE)
SSDB
Motif
Pfam: Peptidase_M16_M Peptidase_M16_C Peptidase_M16 Tn916-Xis
Other DBs
NCBI-GeneID: 100155309
NCBI-ProteinID: XP_001925416
Ensembl: ENSSSCG00000010470
UniProt: F1SC98 A0A4X1UYL0
Position
14:complement(103992035..104106571)
AA seq 1019 aa
MRYRLAWLLHPALPSTFRSVLGARLPPLERLCGFQKKTYSKMNNSAIKRLGNHIIKSPED
KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
REVNAVDSEHEKNVMNDAWRLFQLEKATGNPNHPFSKFGTGNKYTLETRPNQEGIDVRQE
LLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLRQ
LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILSL
EKEATPYPSLIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
NGIQGLRFIIQSEKPPHYLESRVEAFLVTMEKSIEDMAEEAFQKHIQALAIRRLDKPKKL
SAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
NT seq 3060 nt   +upstreamnt  +downstreamnt
atgcggtaccggctagcgtggctgctgcaccccgcgctgcccagcaccttccgctccgtc
ctcggcgcacgcctgccgcccctggagcgcctctgtggtttccaaaaaaagacttacagc
aaaatgaataattcagctatcaagaggctgggaaatcatatcatcaaatctcctgaagat
aaacgagaataccgtgggctagagctggccaatgggatcaaagtacttctcatcagtgat
cccaccacagataaatcatcagcagcacttgatgtacacataggttccttgtcagatcct
ccaaatattgctggcttgagtcatttttgtgaacatatgctatttttgggaacaaagaaa
taccctaaggaaaatgaatacagccagtttctcagtgagcatgcaggaagttcaaatgcc
tttactagtggagagcataccaattactattttgatgtttcccatgaacacctagaaggt
gccctagacaggtttgcacagttttttctatgtcccctatttgatgagagttgcaaagac
agagaagtgaatgcagttgattcagaacatgagaagaatgtgatgaatgatgcctggaga
ctctttcagttggaaaaggctacagggaatcccaatcaccccttcagcaaatttggaaca
ggtaataaatatactctagagactagaccaaaccaagaaggcattgatgtaagacaagag
ctgctgaaattccattctacttattattcatccaacttgatggctatttgtgttttgggt
cgagaatctttagacgacttgactaatctggtcgtaaagttattttctgaagtagagaac
aaaaatgtcccattgccagaatttcctgaacatcctttccaagaagaacatcttagacaa
ctttacaaaatagtacccattaaggatattaggaatctttatgtgacatttcccatacct
gaccttcagaaatactacaaatcaaatcctggtcattatcttggtcatctcattgggcat
gaaggccctgggagtctgttatcagaacttaaatcaaagggctgggtaaatactcttgtt
ggtgggcaaaaggaaggagcccgaggttttatgttttttatcattaatgtggacctgact
gaggaaggattgttacatgttgaagatataattttgcacatgtttcaatatattcagaag
ttacgtgcagaaggacctcaagaatgggttttccaagagtgcaaggacttgaatgctgtt
gcttttaggtttaaagacaaagagaggccacgaggttatacctctaagattgcaggaata
ttgcattactatcccctagaagaagtgctcacagctgaatatttactggaagaatttaga
cctgatttaatagagatggttctcgataaactcagaccagaaaatgttcgggttgcaata
gtttctaaatcttttgaaggaaaaactgatcgcacagaagagtggtacggaacccagtac
aaacaagaagctataccagacgaagtcattaagaaatggcaaaatgctgacctgaatggg
aaatttaaacttccaacgaagaatgaatttattcctacaaattttgagattttgtcatta
gaaaaagaagcaacaccatacccttctcttattaaggatacggctatgagcaaactctgg
ttcaaacaagatgataagtttttcttgcccaaggcctgtctcaactttgagtttttcagc
ccatttgcttatgtggaccccttgcactgtaacatggcctatttgtaccttgagctcctc
aaagactcactcaacgagtatgcatatgcagcagagctagcaggcttgagctatgacctc
caaaataccatctatgggatgtatctctcggtgaaaggttacaatgacaagcagccaatt
ttgctaaagaagattattgagaaaatggctacctttgagattgatgaaaaaagatttgaa
attatcaaagaagcatacatgagatcgcttaacaatttccgagctgagcagcctcaccag
cacgccatgtactacctccgcctgctgatgacagaagtggcctggactaaagatgaatta
aaagaagccctggatgatgtcacccttcctcgccttaaggccttcatacctcagctcctg
tcaaggctgcacatcgaagcccttctccatggaaacataacaaagcaggccgcattagga
attatgcagatggttgaagacacccttattgaacatgcccatacgaaaccgctccttcca
agtcagctggttcggtatagagaagttcagctccctgatagaggctggtttgtttatcag
cagaggaatgaagttcacaataactgtggcatcgagatatactaccagacagacatgcag
agcacctccgagaatatgttcctggagctcttctgtcagatcatctccgagccttgcttc
aacaccctgcgcaccaaggagcagctgggctatatcgtcttcagcgggccacgccgagcc
aacggcatccagggcttacggttcatcatccagtcggaaaagccacctcactacctagag
agcagagtggaagctttcttagttaccatggaaaagtccatagaggacatggcagaagag
gcctttcaaaaacacattcaagccctagcaattcgtcgactagacaaaccaaagaaactg
tccgcagagtgtgctaaatactggggggaaatcatctcccagcaatacaactttgacaga
gataatatagaagttgcatatttaaagacacttaccaaggaagatattatcaaattctat
aaggaaatgttggcagtggatgccccgaggagacataaggtgtctgtccatgttcttgct
agagaaatggattcttgtcccgtggttggagagttcccatgtcaaaatgatataaatttg
tcacaagcaccagccttgccgcaacctgaagtgattcagaacatgaccgagttcaagcgt
ggtttgccactgtttccccttgtgaaaccacatattaacttcatggctgcaaaactctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   RefSeq(pep) (7)   
DNA sequence (17)   
   RefSeq(nuc) (7)   
   GenBank (5)   
   EMBL (5)   
Protein domain (4)   
   Pfam (4)   
All databases (58)   

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