KEGG   Sus scrofa (pig): 100171389
Entry
100171389         CDS       T01009                                 
Symbol
PTPN6
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X2
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04148  Efferocytosis
ssc04520  Adherens junction
ssc04630  JAK-STAT signaling pathway
ssc04650  Natural killer cell mediated cytotoxicity
ssc04660  T cell receptor signaling pathway
ssc04662  B cell receptor signaling pathway
ssc05140  Leishmaniasis
ssc05205  Proteoglycans in cancer
ssc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100171389 (PTPN6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100171389 (PTPN6)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100171389 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100171389 (PTPN6)
   04660 T cell receptor signaling pathway
    100171389 (PTPN6)
   04662 B cell receptor signaling pathway
    100171389 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100171389 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100171389 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    100171389 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ssc01009]
    100171389 (PTPN6)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     100171389 (PTPN6)
Protein phosphatases and associated proteins [BR:ssc01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    100171389 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc PTPlike_phytase Y_phosphatase3 HGAL
Other DBs
NCBI-GeneID: 100171389
NCBI-ProteinID: XP_003355638
Ensembl: ENSSSCG00000025537
UniProt: A0A8D1B809 I3LKA3
Position
5:complement(63762109..63779086)
AA seq 595 aa
MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLKVTHIKVMCEGGRYTVGG
PETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEETA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSD
YINANYVKNKLLGPDENAKTYIASQGCLEATVNDFWQMVWQENTRVIVMTTREVEKGRNK
CVPYWPEVGSQRVYGPYAVTNGGEHDTAEYKLRTLQVSPLANGDLVREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVIQSQKGRESEYGNIT
YPLAMKNAHAKASRTSSKHKEDVYENVHSKNKKEEKVKKQRSADKEKSKGSLKRK
NT seq 1788 nt   +upstreamnt  +downstreamnt
atggtgaggtggtttcaccgagacctcagtgggctggatgctgagaccctgctcaagggc
cgaggggtccacggcagcttcctggctcggcccagtcgcaagaaccagggcgacttctcc
ctctctgtcagggtgggggatcaggtgacccatattcggatccagaactcgggggatttc
tacgacctgtatggaggggagaagtttgcgacgctgacggagctggtggagtattacacg
cagcagcagggcgtcctgcaggaccgagacggcacaatcatccacctcaagtacccgctg
aactgctcggaccccaccagtgagaggtggtaccatggccacatgtctggagggcaggca
gagacactgctgcaggccaagggtgagccctggacatttcttgtgcgtgagagtctcagc
cagcctggagattttgtgctgtctgtgctcagcgaccagcccaaggctggcccgggatcc
ccactcaaagtcacccatatcaaggtcatgtgtgagggtggccgctacacagtggggggt
cccgagaccttcgacagcctcacggacctggtggagcacttcaagaagacggggattgag
gaggcctcgggcgccttcgtctacctgcggcagccatactatgccacgagggtgaacgcg
gctgacatcgagaaccgggtcttggaactgaacaagaagcaggagtcagaggagacagcc
aaggccggcttctgggaggagtttgagagtctgcagaagcaggaggtgaagaacttgcac
cagcggctggaagggcagcggccagaaaacaagagcaagaatcgttacaagaacatcctt
ccattcgaccacagccgagtgatcctgcagggacgggacagtaacatccctgggtctgac
tacattaacgccaactatgtcaagaacaagctgctagggcccgatgagaacgctaagacc
tacatcgccagccagggctgcctggaggccacggtcaacgacttctggcagatggtgtgg
caggagaacacccgtgtcatcgtcatgaccactcgggaggtggagaagggccggaacaaa
tgtgtcccgtactggccagaagtgggcagtcagcgtgtttacggaccctacgctgtcacc
aacggtggggagcacgacacagctgagtacaaactccgcaccttacaggtctccccgctg
gcaaatggggacctggttcgggagatctggcactaccagtacctgagctggcctgaccat
ggggtccccagcgagcctgggggtgtcctcagcttcctggaccagatcaaccagcggcag
gaaagtctgcctcacgcagggcccatcatcgtgcactgcagcgctggcatcggtcgcact
ggtaccatcattgtcatcgacatgcttatggagagcatttccaccaagggcctggactgt
gacatcgacatccagaagaccatccagatggtgcgggcccagcgctcgggcatggtgcag
acagaggcgcagtacaagttcatctacgtggccatcgcccagttcattgaaaccaccaag
aagaagctggaggtcatacagtcgcagaagggccgggagtcggaatatgggaacatcacc
taccccctcgccatgaagaacgctcatgccaaggcctcccgcacctcctccaagcacaag
gaggacgtgtatgagaacgtgcacagtaagaacaagaaggaggagaaggtgaagaagcag
cggtcagcagacaaggagaagagcaagggctccctgaagaggaagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
Protein domain (6)   
   Pfam (6)   
All databases (46)   

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