KEGG   Sus scrofa (pig): 100511102
Entry
100511102         CDS       T01009                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X14
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04010  MAPK signaling pathway
ssc04020  Calcium signaling pathway
ssc04022  cGMP-PKG signaling pathway
ssc04024  cAMP signaling pathway
ssc04218  Cellular senescence
ssc04260  Cardiac muscle contraction
ssc04261  Adrenergic signaling in cardiomyocytes
ssc04270  Vascular smooth muscle contraction
ssc04530  Tight junction
ssc04713  Circadian entrainment
ssc04723  Retrograde endocannabinoid signaling
ssc04724  Glutamatergic synapse
ssc04725  Cholinergic synapse
ssc04726  Serotonergic synapse
ssc04727  GABAergic synapse
ssc04728  Dopaminergic synapse
ssc04911  Insulin secretion
ssc04912  GnRH signaling pathway
ssc04921  Oxytocin signaling pathway
ssc04924  Renin secretion
ssc04925  Aldosterone synthesis and secretion
ssc04927  Cortisol synthesis and secretion
ssc04929  GnRH secretion
ssc04930  Type II diabetes mellitus
ssc04934  Cushing syndrome
ssc04935  Growth hormone synthesis, secretion and action
ssc04973  Carbohydrate digestion and absorption
ssc05010  Alzheimer disease
ssc05020  Prion disease
ssc05022  Pathways of neurodegeneration - multiple diseases
ssc05031  Amphetamine addiction
ssc05207  Chemical carcinogenesis - receptor activation
ssc05410  Hypertrophic cardiomyopathy
ssc05412  Arrhythmogenic right ventricular cardiomyopathy
ssc05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100511102 (CACNA1D)
   04020 Calcium signaling pathway
    100511102 (CACNA1D)
   04024 cAMP signaling pathway
    100511102 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    100511102 (CACNA1D)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100511102 (CACNA1D)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100511102 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100511102 (CACNA1D)
   04929 GnRH secretion
    100511102 (CACNA1D)
   04912 GnRH signaling pathway
    100511102 (CACNA1D)
   04921 Oxytocin signaling pathway
    100511102 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    100511102 (CACNA1D)
   04924 Renin secretion
    100511102 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    100511102 (CACNA1D)
   04927 Cortisol synthesis and secretion
    100511102 (CACNA1D)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    100511102 (CACNA1D)
   04261 Adrenergic signaling in cardiomyocytes
    100511102 (CACNA1D)
   04270 Vascular smooth muscle contraction
    100511102 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    100511102 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    100511102 (CACNA1D)
   04727 GABAergic synapse
    100511102 (CACNA1D)
   04725 Cholinergic synapse
    100511102 (CACNA1D)
   04728 Dopaminergic synapse
    100511102 (CACNA1D)
   04726 Serotonergic synapse
    100511102 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    100511102 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100511102 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100511102 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100511102 (CACNA1D)
   05020 Prion disease
    100511102 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    100511102 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    100511102 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100511102 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100511102 (CACNA1D)
   05414 Dilated cardiomyopathy
    100511102 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100511102 (CACNA1D)
   04934 Cushing syndrome
    100511102 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ssc04040]
    100511102 (CACNA1D)
Ion channels [BR:ssc04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   100511102 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 100511102
NCBI-ProteinID: XP_003132309
UniProt: A0A8D1QJG4 A0A480Y640
Position
13:35568534..35911483
AA seq 2139 aa
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQSNNSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGENQGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTI
SSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIT
ETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLF
IIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGG
PSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARK
ESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVP
AGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSS
AALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDM
LVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMI
VTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNS
DFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPIYNYRVEISIFFIIYIIIVA
FFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWY
VVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFK
PKGYFSDAWNTFDSLIVIGSIVDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEG
IRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQA
VLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLI
INLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPP
LGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRA
VIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKN
STIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEEDVFKRNGALLGNHVNHVNS
DRRESLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPSSTN
ANLNNANMSKVVPGKRPSIGNLEHVSENGHHSSHKHGREPHRRSSIKRSDSGDEQFPTIC
REDPEIHSYFRDPRCLGEREYFSGEECYEDDSSPTGSRQSYGCGYYNRYPGSSLDFERPR
GYHHPQSFSEDDDSPVCYDSRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVPPSPA
FPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPSYRDWTPCYTPLIQ
VERSEALDQVNGSLPSLHRSSWYTDEPGISYRTFTPASLTVPGSFHSKNSDKQRSADSLV
EAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASNLLNGNMHPRANGDVGPI
AHRQDYELQDFGPGYSDEEPDPGRDEEDLADEMICITTL
NT seq 6420 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccaggctccctctttctggtgaaggaccaact
tctcagtcgaataactccaagcaaactgtcctgtcttggcaagccgcaatcgacgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccctatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtgatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaagtcagggggctttgatgtcaaagccctccgc
gcctttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaagaggacccagcaccgtgtgcgttctca
gggaatggacgccagtgcaccgccaatggcacagagtgtaggagtggctgggttggcccc
aatggaggcatcaccaactttgataactttgcctttgccatgctcaccgtgtttcagtgt
atcactatggagggctggacagacgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattttccaaggaaagagagaaggctaaagcacgggga
gacttccagaagctccgggagaagcagcaactggaagaggatctaaagggctacttggat
tggatcacccaagcagaagacattgatcctgagaatgaagaagaaggaggagaggaaagc
aaacggaataccagcatgcccaccagtgagacggagtccgtgaacacggagaatgtgagc
ggggaaggcgagaaccaaggctgctgtgggagcctctgtcaggccatctcgaaatccaag
ctcagccgacgctggcgtcgctggaaccgcttcaatcgcagaagatgtagggctgccgtg
aagtctgtcacattttactggctggttattgtcctggtgtttctcaacactttaaccatt
tcctccgagcactacaaccagcctgactggttgacacagattcaagacattgctaacaaa
gtcctcttggctcttttcacctgtgagatgctggtgaaaatgtacagcttgggtctccag
gcctatttcgtctctctcttcaatcggtttgattgcttcgtggtgtgtggtggaattacc
gaaacaatcttggtagaactggaaatcatgtcccccctgggcatctctgtgtttcgctgc
gtgcggctcttgagaattttcaaagtgaccaggcactggacttccctgagcaacttggtg
gcatccttgctaaactccatgaagtccatcgcatcactgctgcttctgcttttcctcttc
atcatcatcttttccttgcttgggatgcagctatttggcggcaaatttaattttgacgaa
acacagaccaagcggagcacctttgataatttccctcaagcgcttctcacggtgttccag
attctaacaggggaagactggaacgctgtgatgtatgacggcatcatggcatacgggggc
ccgtcgtcttcaggaatgattgtctgcatctacttcatcatcctcttcatatgcggtaac
tatattctgctgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagt
ttgaatactgctcagaaagaggaagccgaagaaaaggaaaggaaaaagattgccagaaaa
gaaagcctggaaaataaaaagaacaacaaaccagaggtcaaccagatagccaacagtgac
aacaaggttaccatcgatgactaccgagaagaggatgaggacaaggacccctacccaccc
tgtgatgtgccagtaggtgaagaggaagaggaggaggaggaggatgaacctgaggtccct
gctggcccccgtcctcgcagaatctctgagttgaacatgaaagagaaaatcgcccccatc
cccgaagggagcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacattttcaccaacctcatcctggtcttcatcatgctgagcagc
gccgcccttgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttgaagatgacgact
tttggagctttcctccacaaaggggctttctgcaggaactacttcaacttactggatatg
ctggtcgttggggtgtctttggtgtcatttgggatccaatccagtgccatctctgtggtg
aagattctgagggtcctaagggtcctgcggccgctaagggcaatcaacagagcgaaagga
cttaagcacgtggtccagtgtgtctttgtggccatccggacaattggcaacatcatgatc
gtcaccaccctcctccagttcatgttcgcctgcatcggggtccagctcttcaagggaaag
ttctatcgctgcaccgatgaggccaaaagcaaccccgaagagtgcagggggctcttcatc
ctctacaaggatggggatgttgatagccctgtggtccgtgagcggatctggcaaaacagc
gatttcaactttgacaacgtcctctcagctatgatggctctgttcacggtgtccacgttc
gagggctggcctgcgttgctgtacaaagccatcgactcaaacggagagaacgttggcccc
atctacaactaccgcgtggagatctctatcttcttcatcatctacatcatcatcgtagca
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacgtttcaggagcagggggag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagcacgtcccctgcggaggtacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtctaagatgtttaatgacgccatggacattctg
aatatggtcttcaccggcgtgttcactgtcgagatggttttgaaagtcattgcatttaaa
cctaaggggtactttagtgatgcctggaacacgtttgactccctcatcgtaatcggcagc
attgtagacgtggccctcagcgaagccgacaactctgaagaaagcaatagaatctccatc
acctttttccgtcttttccgagtgatgcgattggtgaagcttctcagcaggggggaaggc
atccggacgctgctgtggacttttattaagtccttccaggcgctcccatacgtcgccctt
ctcattgccatgctcttcttcatctatgcggttatcggcatgcagatgtttgggaaagtt
gccatgagagataacaaccagatcaacaggaacaacaatttccagacctttcctcaggcg
gtgctgctgctcttcaggtgtgcaacaggggaggcctggcaggaaattatgctggcctgc
ctcccaggaaagctctgtgaccctgaatctgattataaccctggggaggagtacacatgt
gggagcaacttcgccatcgtttacttcatcagcttttacatgctttgcgcatttctgatc
atcaacctgtttgtggctgtcatcatggacaattttgattatctgacccgggactggtct
attctgggacctcaccacttagatgaattcaaaagaatatggtctgaatatgatcctgag
gcaaagggaaggatcaagcacctggacgtggtcactctgctccgccgcatccaacctccc
ctggggtttgggaaactgtgcccacacagagtagcctgcaagaggctggttgctatgaac
atgccgctcaacagtgatgggacagtcatgtttaatgcaactctgtttgccttggttcga
acggctcttaaaatcaagacggaagggaacctggaacaagctaatgaggaactccgagct
gtgatcaagaaaatctggaagaaaaccagcatgaaactacttgaccaagttgtccctcca
gctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacaggactac
tttaggaaattcaagaaacggaaagaacaaggactggtgggaaaataccctgcgaagaac
agcacaattgccctacaggcgggattaaggacactgcacgacattgggccagaaatccgg
cgtgctatatcatgtgatttgcaagatgatgagccggaggaaacaaaacgcgaagaagaa
gaagatgtattcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagt
gataggagagagtcccttcagcagaccaataccacccaccgtcccctgcatgtccaaagg
ccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagcaggaaattcg
gtgtgtcataaccatcataaccataattccataggaaagcaagttcccagctcaacaaat
gccaatctcaataatgccaatatgtccaaagttgtccccggaaagcggcccagcattggg
aatcttgagcatgtgtctgaaaatgggcatcattcctcccacaagcatggccgtgagcct
cacagaaggtccagtattaaaaggtctgactcaggagatgagcagtttccaaccatttgc
cgggaagaccccgagatccacagctacttcagggacccccgctgcctgggggagcgggag
tatttcagtggtgaggaatgttacgaggatgacagctcaccaaccgggagcaggcaaagc
tatggctgcggctactacaaccgatatccaggcagcagcttagactttgagcggcctcga
ggctaccatcaccctcaaagcttctcagaggacgatgactcaccggtttgctatgattcc
cggaggtctccaaggagacgcctactacctcccaccccaacatcccaccggagatcctcc
ttcaacttcgagtgcctgcgccggcagagcagccaggaggaggtcccgccatcccccgcc
ttcccccaccgcacagccctgcctctgcacctgatgcagcaacagatcatggcagttgct
ggcctcgattccagtaaagcccagaagtactcgccaagccactcaacccggtcgtgggcc
acccctccggcgacgccgtcataccgggactggacaccatgctacacccccctgatccag
gtcgagcggtcagaggccctggaccaggtcaatggcagcctgccgtccctgcaccgcagc
tcgtggtacacagatgagccgggcatctcctatcggactttcacaccagccagcctgact
gtccctggcagcttccacagcaaaaacagcgacaagcagaggagcgcagacagcttggtg
gaggcggtcctgatatctgaaggcttaggacggtatgccagggacccaaagtttgtgtca
gcgacaaaacacgaaatcgccgatgcctgtgacctaaccattgatgagatggagagtgca
gccagcaacctgctgaatggaaacatgcatccccgggccaacggggatgtgggccccatc
gcacaccggcaggattacgagctccaggacttcgggcccggctacagcgacgaggagccg
gaccctgggagggacgaggaggacctggcagatgaaatgatttgcatcaccaccctgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (16)   
   UniProt (2)   
   RefSeq(pep) (14)   
DNA sequence (14)   
   RefSeq(nuc) (14)   
Protein domain (5)   
   Pfam (5)   
All databases (98)   

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