KEGG   Sus scrofa (pig): 100513348
Entry
100513348         CDS       T01009                                 
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
  KO
K08860  eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04137  Mitophagy - animal
ssc04140  Autophagy - animal
ssc04141  Protein processing in endoplasmic reticulum
ssc04210  Apoptosis
ssc04932  Non-alcoholic fatty liver disease
ssc05010  Alzheimer disease
ssc05012  Parkinson disease
ssc05014  Amyotrophic lateral sclerosis
ssc05020  Prion disease
ssc05022  Pathways of neurodegeneration - multiple diseases
ssc05160  Hepatitis C
ssc05162  Measles
ssc05168  Herpes simplex virus 1 infection
ssc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100513348 (EIF2AK3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100513348 (EIF2AK3)
   04137 Mitophagy - animal
    100513348 (EIF2AK3)
  09143 Cell growth and death
   04210 Apoptosis
    100513348 (EIF2AK3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    100513348 (EIF2AK3)
   05162 Measles
    100513348 (EIF2AK3)
   05168 Herpes simplex virus 1 infection
    100513348 (EIF2AK3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100513348 (EIF2AK3)
   05012 Parkinson disease
    100513348 (EIF2AK3)
   05014 Amyotrophic lateral sclerosis
    100513348 (EIF2AK3)
   05020 Prion disease
    100513348 (EIF2AK3)
   05022 Pathways of neurodegeneration - multiple diseases
    100513348 (EIF2AK3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100513348 (EIF2AK3)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100513348 (EIF2AK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ssc01001]
    100513348 (EIF2AK3)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100513348 (EIF2AK3)
Protein kinases [BR:ssc01001]
 Serine/threonine kinases: Other
  PEK family [OT]
   100513348 (EIF2AK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PQQ_2 Kinase-like Kdo ABC1
Other DBs
NCBI-GeneID: 100513348
NCBI-ProteinID: XP_003124973
Ensembl: ENSSSCG00000008208
Vega: OTTSUSG00000001778
UniProt: A0A480XY09
Position
3:57423894..57506247
AA seq 1116 aa
MERATRPGSLARALLLLLLLLGLSTGTVVARRASELPTPTSKAAFGLGAAAAPTSAARVP
ASGAVTAAEVTVEDAEALPAAAGEQEPRDPEPDDDPDLRPFGRSLVIISTLDGRIAALDP
ENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVES
LLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDEMEQEEDILLLQR
TQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEQSKIIVDVEE
QEAATTDTVIKVSVADWKVMAFSKKGGQLEWEYQFCTPIASAWLVKDGKVIPISLFDDTS
YVTNDGVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNSE
NTIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGY
YLPYYKRERSKRSTQITVRFLDNPNYNKNIRKKDPVLLLHWWKEIVGTILFCIIATTFIV
RRLFHPHPHRQRKESETQCQTENKYDSVSAEANDSNWNDVKNSGYVSRYLTDFEPIQCMG
RGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLE
APPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRVDPGSTKEHIEIIAPSPRSSR
SFSMGISCGQTSSSESQFSPLELSGMDHGDASQSVDAAYNLQDSCLTDCDLEDGTLDGSN
DGHSFELCPSESSPYIRSRERTSSSIVFEDSGCDNASSKEEPRMNRLPIGNHCANKLTAL
QHSSSKSSSEPTLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWL
NSRCTIEERERSVCLHIFLQIVEAVEFLHSKGLMHRDLKPSNIFFAMDDVVKVGDFGLVT
AMDQDEEDEMVLTPMPGYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYP
FGTQMERVRILTDVRDLKFPPLFTQKYPREFAMVQDMLSPSPTERPEAANIIENAIFEDL
EFPGKTVLRQRSRSMSSSGTKHSRHSSSSHSPLPSN
NT seq 3351 nt   +upstreamnt  +downstreamnt
atggagcgcgccacccgcccggggtcgctggcgcgggcgctgttactgttgctgctgcta
ctggggctctcgaccggaacggtggtcgcgcggcgcgcctcggagctcccgacaccgacc
tcgaaggcggcgttcggcctgggggccgcggccgctcccacctcggccgcgcgggtgccg
gcttccggcgccgtgactgcagccgaggtgacagtggaggacgccgaggcgctaccggcg
gccgcgggcgagcaggagccacgggatccggaacccgacgacgatcctgaccttcggccg
ttcggcagatcactagtgattatcagcactttggatggccgaattgctgccttggatcct
gagaatcatggtaaaaagcagtgggatttggacgtgggatccgggtccttggtgtcatcc
agccttagcaaaccagaggtatttgggaataagatgatcatcccttccctggatggagac
ctcttccagtgggaccgggaccgggagagtatggaaacagttccgtttacagttgaatca
cttcttgaatcttcttataaatttggagatgatgttgtcttggttggaggaaagtctctc
actacatacggactcagtgcatatagtggaaaggtgaggtacatctgctcagctttgggt
tgtcgccaatgggataatgacgaaatggaacaagaagaagacatcctgcttttgcagcgc
acccagaaaaccgtgagagctgtcggacctcgcagtggcaacgagaagtggaatttcagc
gttggccactttgaacttcggtatattccagacatggaaactagagcgggatttattgaa
agcaccttaaaacccagtggaaacaaagaacagtctaaaattattgtagatgtggaagaa
caggaagctgccacgacggacaccgtgataaaggtctcggttgctgattggaaagttatg
gcgtttagtaagaagggaggacaactggagtgggaataccagttttgtactcctattgca
tctgcctggttggtcaaggatggcaaagtcattcccatcagcctttttgatgatacaagt
tacgtcaccaatgatggagttttagaagatgaagaagacattgtagaagctgcccgagga
gccacagaaaacagcgtttacttgggaatgtacagaggccagctgtatctgcagtcatca
gttagaatttcagagaagtttcctacaagtcctaaggccttggaatctgtcaatagtgaa
aatacaattattcctttgccaacaatcaaatggaaacccttaattcattctccttccaga
actccagtcttggtagggtctgatgaattcgacaagtgtcttagtaatgataagttttct
catgaagagtacagtaatggtgccctctcaatcttgcagtatccctatgataatggttat
tacctgccatactacaagcgggaaaggagcaaacggagcacgcagatcacagtcagattt
ctcgacaacccgaattacaacaagaacatccgcaaaaaggaccctgtgctccttttgcac
tggtggaaggaaatagttgggaccatcctcttttgtatcatagcaacaactttcatcgtg
cgcagactcttccatcctcatcctcaccgacaaaggaaggaatctgaaactcagtgtcaa
actgaaaacaagtatgattctgtaagtgccgaagctaacgacagtaactggaatgacgta
aaaaattccggatatgtatcacgatatctaacagattttgaaccaattcagtgcatgggt
cgtggggggtttggagttgtctttgaagctagaaacaaagtagacgactgcaattatgcc
atcaagagaatccgtctcccgaacagggaattggctcgggaaaaggtaatgcgagaagtt
aaagccttagccaagcttgaacacccaggaattgttagatatttcaatgcttggctggaa
gcaccaccagagaagtggcaagaaaaaatggatgaaatttggctgaaagatgaaagcaca
gactggccactcagttcgccgagtccaatggatgcaccatccgttaaaatacgcagagtg
gatcctggctctaccaaggaacatattgaaatcatagctccttcaccacgaagcagcagg
tctttctctatggggatttcctgtggccagacgagttcatcggagagccagttctctccc
ctggaactttccggaatggaccatggagatgccagccagtcagtggatgcagcgtacaac
ctccaggacagctgccttacagactgtgacttggaggacggtactctggacggcagcaat
gatgggcactcctttgaactttgtccttctgaatcttctccctacatcaggtctagggag
cgaacctcctcttccatagtgtttgaagattctggctgtgataacgcatccagcaaagaa
gagcccagaatgaaccgactgcctattggcaaccactgtgctaataaactcactgcactc
cagcattccagtagcaaatcttcctctgaacctactctgtctatttctcctccaagaccg
accactttaagtttagacctcactaaaaacactacggaaaaactccagcccagttcaccg
aaagtgtatctgtacatccagatgcagctgtgcagaaaggaaaacctcaaagactggctg
aacagccgctgcaccatcgaggagcgagagaggagcgtgtgtctgcacatcttcctgcag
attgtggaggcggtagaatttctgcacagcaaagggctcatgcacagggacctcaagcct
tccaatatattctttgcaatggatgatgtggtcaaggttggagactttggattggtgact
gcaatggaccaggatgaggaagacgagatggttctgaccccaatgccagggtacgccaga
cacacgggacaagtggggaccaagctatatatgagcccagagcagattcatggaaacagc
tactctcataaagtggacatcttttctttaggcctcattctgtttgaattgctgtaccca
ttcggcactcagatggagagggtccggatcttaactgatgtaagagatctcaaatttcca
ccactgtttactcagaaatatcctcgggagtttgcgatggtgcaggacatgctctcccca
tcccccaccgagcggcccgaagctgcaaacatcattgaaaatgcaatatttgaggacttg
gagtttccgggaaaaacagtgctcagacagaggtctcgctccatgagctcatcaggaacg
aaacattcaagacactccagcagctcccatagccctttgccaagcaattaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (14)   
   KEGG PATHWAY (14)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (6)   
   Pfam (6)   
All databases (60)   

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