KEGG   Sus scrofa (pig): 100515445
Entry
100515445         CDS       T01009                                 
Symbol
FLT3
Name
(RefSeq) receptor-type tyrosine-protein kinase FLT3 isoform X2
  KO
K05092  fms-related tyrosine kinase 3 [EC:2.7.10.1]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04010  MAPK signaling pathway
ssc04014  Ras signaling pathway
ssc04151  PI3K-Akt signaling pathway
ssc04640  Hematopoietic cell lineage
ssc05200  Pathways in cancer
ssc05202  Transcriptional misregulation in cancer
ssc05221  Acute myeloid leukemia
ssc05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100515445 (FLT3)
   04014 Ras signaling pathway
    100515445 (FLT3)
   04151 PI3K-Akt signaling pathway
    100515445 (FLT3)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100515445 (FLT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100515445 (FLT3)
   05202 Transcriptional misregulation in cancer
    100515445 (FLT3)
   05230 Central carbon metabolism in cancer
    100515445 (FLT3)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    100515445 (FLT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ssc01001]
    100515445 (FLT3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ssc04090]
    100515445 (FLT3)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100515445 (FLT3)
Protein kinases [BR:ssc01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   100515445 (FLT3)
CD molecules [BR:ssc04090]
 Proteins
  100515445 (FLT3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase ig Ig_3 I-set Ig_2 APH
Other DBs
NCBI-GeneID: 100515445
NCBI-ProteinID: XP_005668350
Ensembl: ENSSSCG00000009314
Vega: OTTSUSG00000002344
UniProt: A0A4X1TMR8
Position
11:complement(5370475..5455439)
AA seq 971 aa
MIFETITNQDLPVIQCILINHRNNDSSVGTTSSNPMASEAQEDLGCALRPKSKGTVYEAA
TVEVDVSASITLQVLVATPGNISCLWVFKNSSRNCQPHFDLQNRGVVSMVILKMTETQAG
EYQLFIQSEAVNYTVLFTVSIRNTLLYTLRRPYFRKMENQDALVCISEGIPEPTVEWVFC
DAQSDSCKGESPAVVTKEESVLHELFGTDIRCCARNELGRECTKLFTIDLNQTPQTTPPQ
LFLKVGEPLWIRCKAVHVNHGFGLSWELENKALEEGSCFEMSTYSTNRTMIRILFAFVSS
VGRNDTGYYTCSSSEHPSKSALVTILEKGFINASKSNEDYEIDQYEEFCFSVRFKAYPQI
RCTWTFSRKSFPCEQRGLDDGYSISKFCNHKHQPGQYIFHAENDDAQFTKMFTLNIRRKP
QVLAEASASQASCSSDGYPLPSWTWKKCSDKSPNCTEEITEGIWNKKANRKVFGQWISSS
TLNMSEAVKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGLCLPFIAVLT
MLICHKYKKRFRYESQLQMVQVTGSLDNDYFYIDFREYEYDLKWEFPRENLEFGKVLGSG
AFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTHLGSHENIVNLLG
ACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPG
SREVQIHPDSDPISGFNGNSFQSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGM
EFLEFKSCVHRDLAARNVLVTHGKVVKIGDFGLARDIMSDSNYVIRGNARLPVKWMAPES
LFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPADANFYKLIQSGFKMDQPFYATEEIY
FIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNTDGRASERPLYQNRRPFSRQVD
SGPPSPQAEDS
NT seq 2916 nt   +upstreamnt  +downstreamnt
atgatctttgagactattacaaatcaagacctgcctgtgatccagtgcattttaatcaac
cataggaacaatgattcatcggtggggaccacgtcatcgaatcctatggcgtcagaagcc
caggaagacctgggttgtgccttgaggcccaagagcaaggggacagtctacgaagcagcc
actgtggaggtggacgtgtccgcgtccatcacgctgcaggtgctggtcgccaccccaggg
aacatttcctgcctctgggtctttaaaaatagctcccggaattgccagccacacttcgac
ttgcaaaacagaggagttgtttccatggtcattttgaaaatgacagaaacccaggctgga
gaataccaactttttattcagagcgaagctgtcaattacacagtgttgtttacagtgagt
ataagaaatacactgctttacacactaaggagaccctactttagaaaaatggaaaaccag
gacgccctggtctgcatctctgagggcattccagagcccaccgtggaatgggtgttctgc
gatgcgcagagtgacagctgtaaaggagaaagtccagctgttgttacgaaggaggagagc
gtactccatgagttatttgggactgacataaggtgctgtgcaaggaacgagctgggcagg
gagtgtaccaagctcttcactatagatctaaaccaaactcctcagaccacaccgccacag
ttatttctgaaagtaggggagcccttgtggataaggtgcaaagctgttcacgtaaaccac
ggattcgggctcagctgggaattagagaataaagccctggaggagggcagctgctttgag
atgagtacctattccacaaacagaactatgatacggattctgtttgcttttgtatcatca
gtgggaagaaacgacactggatattacacttgttcctcttcagagcatcccagtaaatca
gctttggtcaccatcctagaaaagggatttataaatgcttccaaatcaaatgaggattat
gaaattgaccagtatgaagagttttgcttttctgtcaggtttaaagcgtatccacaaatc
aggtgcacgtggaccttctctcgcaaatcatttccttgtgagcaaaggggactcgacgac
gggtacagcatatctaagttttgcaaccataaacaccagccaggacaatacatcttccat
gcagaaaatgacgacgcccagttcacaaagatgttcacgctgaatataagaaggaaaccg
caagtgctggccgaggcatcggcaagtcaggcttcctgctcctctgatggttacccgtta
ccgtcttggacctggaagaagtgttcagacaagtctcccaactgcacggaagagatcacg
gaaggcatctggaataaaaaggccaacaggaaagtatttggacagtggatttccagcagc
actctgaacatgagcgaggctgtcaaagggtttctggtgaagtgctgtgcctacaattcc
ctgggcacgtcttgtgaaacgatcctcttaaactcaccaggccccttccctttcatccag
gacaacatctcattctatgcaacaattggcctctgtcttcccttcatcgccgttttaacc
atgctaatttgtcacaagtacaaaaagcgattccggtacgaaagccagctgcagatggtc
caggtgacggggtccctggataacgactacttctacatcgacttcagagaatatgaatat
gacctcaaatgggagtttcccagggaaaatttagaatttgggaaggttctgggatccggc
gcttttggaaaagtgatgaacgcaactgcctatggaatcagtaaaactggagtgtcaatc
caggtggcagtcaaaatgctgaaagaaaaagcagacagctcggaacgagaggctctcatg
tctgaactcaaaatgatgacccacctgggcagccatgagaatatagtgaacctgctgggc
gcctgcaccctgtcagggcccatttacttgatttttgaatattgttgctacggtgatctt
ctcaactatctaagaagtaaaagagagaaatttcataggacatggaccgagattttcaag
gaacataatttcagtttttatcctactttccaatcacacccaaattccagtatgccgggt
tcaagagaagttcaaatacacccagactcggatcctatctcaggattcaatgggaattca
tttcaatctgaagatgaaattgaatacgaaaaccagaaaaggctggaggaggaagaggac
ttgaatgtcctcacctttgaagaccttctttgctttgcctatcaagtggccaaagggatg
gaatttctggaatttaagtcgtgcgttcacagagacctggcagccaggaacgtcctggtg
acccacgggaaagtggtgaagatcggtgactttggcctggctcgcgacatcatgagtgac
tccaactacgtgatccggggcaatgcccgtctgcctgtcaagtggatggctcccgaaagc
ttgtttgagggaatctacaccattaagagcgatgtctggtcatacggaatactgctctgg
gaaatattctcgcttggtgtgaatccttaccctgggattccggctgatgctaatttctac
aaactcatccagagcggatttaaaatggatcagccattttacgctacggaagaaatatac
tttataatgcagtcctgctgggcttttgactccaggaaacggccctccttcccaaacctg
acttcattcttgggatgtcagctggcggatgcagaagaagcgatgtaccagaacaccgat
ggccgcgcttccgaacgtcctctctaccaaaacaggcgacctttcagcagacaggtggat
tcagggccaccctctccacaggctgaagattcgtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (41)   

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