KEGG   Sus scrofa (pig): 100519700
Entry
100519700         CDS       T01009                                 
Symbol
AMBRA1
Name
(RefSeq) activating molecule in BECN1-regulated autophagy protein 1 isoform X3
  KO
K17985  activating molecule in BECN1-regulated autophagy protein 1
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04137  Mitophagy - animal
ssc04140  Autophagy - animal
ssc05010  Alzheimer disease
ssc05014  Amyotrophic lateral sclerosis
ssc05016  Huntington disease
ssc05017  Spinocerebellar ataxia
ssc05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100519700 (AMBRA1)
   04137 Mitophagy - animal
    100519700 (AMBRA1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100519700 (AMBRA1)
   05014 Amyotrophic lateral sclerosis
    100519700 (AMBRA1)
   05016 Huntington disease
    100519700 (AMBRA1)
   05017 Spinocerebellar ataxia
    100519700 (AMBRA1)
   05022 Pathways of neurodegeneration - multiple diseases
    100519700 (AMBRA1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ssc04131]
    100519700 (AMBRA1)
   03029 Mitochondrial biogenesis [BR:ssc03029]
    100519700 (AMBRA1)
Membrane trafficking [BR:ssc04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    100519700 (AMBRA1)
Mitochondrial biogenesis [BR:ssc03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    100519700 (AMBRA1)
SSDB
Motif
Pfam: WD40 ANAPC4_WD40 eIF2A Acyl_CoA_thio
Other DBs
NCBI-GeneID: 100519700
NCBI-ProteinID: XP_003122892
Ensembl: ENSSSCG00000013262
UniProt: A0A8D1LNJ9 A0A287BIG8
Position
2:15935354..16119082
AA seq 1206 aa
MKVVPEKNAVRILWGRERGTRTFGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLA
FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV
RIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEM
ERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLL
HNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGP
TRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSV
LRQQEGGSQASVYTSATEGRGFPASGLAAESDGGNGSSQSNPGSIRHELQCDLRRFFLEY
DRLQELDQSLNGEAPQAPQAQEMLNNNTESERPGPSHQPTPHSSENNSNLSRGHLNRCRA
CHNLLTFNNDTLRWERSTPNYSSGEASSSWQVPSTFEGMPSSGSQLPPLERTEGQTPSSS
RLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLR
RRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQ
NRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFL
LPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKF
DLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHN
LGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETS
MRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWD
QLNETVFTVHSSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQ
LQNAETQTEREIQEPGTAASGPGEGEGSELGASGEDALSRIQRLMAEGGMTAVVQREQST
TMASMGGFGNNIIVSHRIHRSSQTGTEPGAARTSSPQPSTSRGLLPEAGQLAERGLSPRT
ASWDQPGTPGREPPLPPSSPVPPPAPLPSTEGPTLHCDLTSNSHLLDSGGSSRGEAAGPS
GEPRNR
NT seq 3621 nt   +upstreamnt  +downstreamnt
atgaaggttgttccagagaagaatgctgtccggatactctgggggcgagaacggggcact
cgaacctttggagcccagcggcttctgcaggagctggtggaagataaaacccgatggatg
aaatgggagggcaagagagtggaactgccggatagtccacgctctacctttttactggcc
ttcagcccagacaggactctcttggcctccacccatgtaaaccataatatctatatcaca
gaggtgaagacgggcaagtgtgttcactctctgattgggcaccgccgcactccatggtgt
gtcactttccatcccaccatctcaggccttattgcttctggctgcctagatggggaggtt
aggatttgggatttacacggtggcagtgaaagctggttcacagatagcaacaatgccatt
gcctctctggctttccaccctacggcccagctcctgctgattgccactgccaacgagatc
cacttttgggactggagtcgacgggaaccttttgctgtggtgaagacagccagcgagatg
gaacgagtccgtctggtgagatttgatcctcttggacactacttactcacagcaattgtt
aacccctctaatcagcagggcgatgacgaaccagagatccccatagatggaacagaatta
tcccactatcgtcagcgtgccctcctgcaatcacagccagtgcgccggacacctctcctc
cacaatttcctgcacatgctgtcctcccgttcctcgggcatccagaccgagcccttccat
cccccggagcaggcctcgtcaacgcagcaggaccagggcctcctgaaccggccgtctgcc
ttcagtacagtccagagcagcactgccggcaacacgctccgcaacctcagtctgggtccc
acccgtcgctctttgggaggccctctgtctagtcacccttcgaggtatcaccgagaaata
gctcctgggctgacgggatctgagtggacccggacagtgctcagtctgaactcccgctct
gaggcggaatccatgcccccgcccaggaccagtgcctcttcggtgagtttgttgtctgtg
ctgagacagcaggaaggtggctctcaagcatctgtctacacttcagccacagaagggagg
ggatttccagcttcagggttggcagctgaatccgatggagggaatggctccagccagagc
aacccaggcagcattcgccatgagcttcagtgtgacctgagacgtttctttttggagtat
gaccggcttcaggagctggaccagagcctgaatggggaagccccccaggccccgcaggcc
caggaaatgctcaacaataacactgaatccgagagaccaggcccctcccaccagcccacc
ccgcatagcagtgagaacaactccaacctgtcccgtggccacctgaaccgctgccgcgct
tgccacaatctcctgaccttcaacaacgacaccctgcgctgggaaagaagcacacctaac
tactcctctggcgaggccagctcctcctggcaggtccccagtacctttgagggcatgccc
tcaagtggcagccagttgccacctctcgagcggactgagggccaaacgcctagctccagc
aggctggagttgagcagctctgctagtccgcaggaggagaggactgtgggggtggccttt
aaccaggagacaggccactgggaacgaatttatacccagtccagcagatctggaactgtg
tcacaggaggccttacatcaggacatgcctgaggaaagctccgaggaagattcactcagg
aggaggctgctggagtcttccctcatttcattatcccgttatgatggagcaggatccaga
gagcacccaatttacccagacccagcgagattatctcccgctgcgtactacgcccagagg
atgatccagtatctctcccggagagacagtatccgccagcgttccatgcgctaccaacag
aaccgcctccgttcttccacctcctcctcttcctcagacaaccagggtccatcagtcgag
ggaaccgacttggaatttgaggactttgaggacaatggtgacagatccaggcaccgagct
ccacgcaacgcccggatgtctgcaccttcacttggacgctttgtcccaaggcgtttcttg
ctgcctgagtacttgccttatgctgggatttttcatgaacgtggacagcctggcttggct
actcactcttctgttaacagggtcctggcaggggcagtgattggtgatggacagtctgcc
gtggccagtaatattgccaataccacctaccggctccagtggtgggacttcactaagttt
gacctcccagaaatcagtaatgcctccgtgaatgtgctggtgcagaactgcaagatctac
aatgatgccagctgtgacatttctgcagatggccagctcctggcagctttcatccctagc
agccaaaggggctttcccgatgaaggcatcctggcagtgtactctctggccccccataac
ctgggcgaaatgctctacaccaagcgatttggtcccaatgccatttcggtgagcctgtcc
ccgatgggtcgatatgtgatggtgggcttggcctcacggaggatcctgctgcatccctcc
acggagcacatggtggcccaggtcttcaggctgcagcaggcccatggtggcgagacctcc
atgcggagagttttcaacgtcctttaccccatgcctgctgaccaacggagacatgtcagc
atcaattctgcccggtggctgcccgagccggggctcggactggcctatggtaccaacaag
ggagacctggtgatctgccgaccagaggccttaaactctggcgttgagtactactgggac
cagctgaacgagactgtcttcaccgtccactccagcagccggagcagcgagaggcctgga
accagcagagccacatggaggaccgacagagatatgggcctgatgaatgcaattgggctg
cagccccggaaccccaccacctcggtgacatctcagggcacccagactctggcccttcag
ctgcagaatgctgaaacacagacggagagggagatacaggagccagggacagcagcttcg
ggtcctggtgaaggggagggctcagagctcggtgccagtggggaagacgcgctcagcagg
atccagcggctgatggcggaggggggcatgacagccgtggtgcagcgagagcagagcacc
accatggcctccatgggcggcttcggcaacaacatcatcgtcagccaccgcatccaccgc
agctcccagacgggcaccgagcccggggccgcgcgtacctcctcgccccagccctccacc
tctcggggactgcttccggaagctgggcagctggctgagcgaggcctgagcccccggaca
gcctcctgggaccagccgggtacccctgggcgggagccacccctgcccccctcctcccct
gtccctcctcctgcgccccttcccagcactgagggaccaaccctgcactgcgacctgacc
agtaacagccaccttcttgacagcgggggcagcagcaggggggaggctgcgggccccagt
ggggagccacggaacaggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (12)   
   UniProt (2)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (4)   
   Pfam (4)   
All databases (59)   

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