KEGG   Sus scrofa (pig): 100525766
Entry
100525766         CDS       T01009                                 
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04010  MAPK signaling pathway
ssc04012  ErbB signaling pathway
ssc04014  Ras signaling pathway
ssc04024  cAMP signaling pathway
ssc04062  Chemokine signaling pathway
ssc04360  Axon guidance
ssc04392  Hippo signaling pathway - multiple species
ssc04510  Focal adhesion
ssc04625  C-type lectin receptor signaling pathway
ssc04650  Natural killer cell mediated cytotoxicity
ssc04660  T cell receptor signaling pathway
ssc04666  Fc gamma R-mediated phagocytosis
ssc04810  Regulation of actin cytoskeleton
ssc05132  Salmonella infection
ssc05170  Human immunodeficiency virus 1 infection
ssc05205  Proteoglycans in cancer
ssc05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100525766 (PAK1)
   04012 ErbB signaling pathway
    100525766 (PAK1)
   04014 Ras signaling pathway
    100525766 (PAK1)
   04392 Hippo signaling pathway - multiple species
    100525766 (PAK1)
   04024 cAMP signaling pathway
    100525766 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100525766 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100525766 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100525766 (PAK1)
   04650 Natural killer cell mediated cytotoxicity
    100525766 (PAK1)
   04660 T cell receptor signaling pathway
    100525766 (PAK1)
   04666 Fc gamma R-mediated phagocytosis
    100525766 (PAK1)
   04062 Chemokine signaling pathway
    100525766 (PAK1)
  09158 Development and regeneration
   04360 Axon guidance
    100525766 (PAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100525766 (PAK1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    100525766 (PAK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100525766 (PAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100525766 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ssc01001]
    100525766 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ssc04131]
    100525766 (PAK1)
   03036 Chromosome and associated proteins [BR:ssc03036]
    100525766 (PAK1)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100525766 (PAK1)
Protein kinases [BR:ssc01001]
 Serine/threonine kinases: STE group
  STE20 family
   100525766 (PAK1)
Membrane trafficking [BR:ssc04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100525766 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    100525766 (PAK1)
Chromosome and associated proteins [BR:ssc03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     100525766 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT Kdo YrbL-PhoP_reg
Other DBs
NCBI-GeneID: 100525766
NCBI-ProteinID: XP_005667221
Ensembl: ENSSSCG00000014878
Vega: OTTSUSG00000000948
UniProt: A0A480LCM5 A0A4X1UCQ5
Position
9:complement(11830095..11973074)
AA seq 446 aa
MPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNT
LNVKTVSETPAVPPVSEDEDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVAT
SPISPTESTTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQG
ASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDE
LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGM
DGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIE
GEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQ
FLKIAKPLSSLTPLIAAAKEATKNNH
NT seq 1341 nt   +upstreamnt  +downstreamnt
atgccagagcagtgggcccgcttgcttcagacgtcaaacatcaccaagtcggagcagaag
aaaaacccgcaggctgttctggatgtactggaattttataactcgaagaagacctccaac
agccagaagtacatgagctttacagataaatcagctgaggattataattcttctaacact
ttgaatgtgaagacggtgtccgagactcctgccgtgccacccgtttcagaagatgaagat
gatgatgatgatgccaccccacctccagtgattgctccacgtccggagcacacgaaatct
gtatacacacggtctgtgattgaaccacttcctattactccaactcgggatgtggctaca
tctcccatttcacctactgagagcactaccactccaccggatgccctgactcggaatact
gagaagcagaagaagaagcccaaaatgtctgatgaggagatcttggagaaattacggagc
atagtgagtgtgggtgatcctaagaagaaatacacacgatttgagaagattggacaaggt
gcttcgggcactgtgtacactgcaatggatgtggccacaggacaggaggtggccattaag
cagatgaatcttcagcagcagccgaagaaagagctgattattaatgagatcctagtcatg
agggaaaacaagaacccaaatattgtgaactacttggacagttacctcgtgggagatgaa
ctgtgggttgtcatggaatacttggctggaggttctttgacagatgtggtgacagaaacg
tgcatggatgaaggccagattgcagctgtgtgtcgggagtgcctgcaggctttggaattt
ctgcattcaaatcaagttattcatagagacatcaagagtgacaacatcctgttgggaatg
gatggctctgtcaagctaactgattttggattctgtgcccagatcaccccagagcagagc
aaacggagcaccatggtgggaaccccatattggatggcaccagaggttgtaactcggaag
gcctatggacccaaggttgacatttggtccctgggcatcatggccattgaaatgattgaa
ggggaacccccatacctcaatgaaaaccctctgagagccttgtacctcattgccaccaat
gggaccccagagcttcagaacccagagaagctgtcagctatcttccgagactttttgaac
cgctgtcttgagatggatgtggagaagagaggttcagctaaagagctgctacagcatcag
ttcctgaagattgcaaagcccctctccagcctcactccactgattgctgcagcaaaggag
gcaaccaagaacaatcactaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (11)   
   UniProt (2)   
   RefSeq(pep) (9)   
DNA sequence (11)   
   RefSeq(nuc) (9)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (71)   

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