KEGG   Sus scrofa (pig): 100620614
Entry
100620614         CDS       T01009                                 
Symbol
ALOX12
Name
(RefSeq) arachidonate 12-lipoxygenase, 12S-type isoform X2
  KO
K00458  arachidonate 12-lipoxygenase [EC:1.13.11.31]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00590  Arachidonic acid metabolism
ssc01100  Metabolic pathways
ssc01523  Antifolate resistance
ssc04726  Serotonergic synapse
ssc04750  Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    100620614 (ALOX12)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    100620614 (ALOX12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100620614 (ALOX12)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100620614 (ALOX12)
Enzymes [BR:ssc01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.31  arachidonate 12-lipoxygenase
     100620614 (ALOX12)
SSDB
Motif
Pfam: Lipoxygenase PLAT
Other DBs
NCBI-GeneID: 100620614
NCBI-ProteinID: XP_003483140
Ensembl: ENSSSCG00000017930
Vega: OTTSUSG00000002442
UniProt: A0A8D0Y413 F1RF49
Position
12:52401861..52414913
AA seq 663 aa
MGRYRIRVATGDSIFAGSLNSVQLGLVGARGETELELQLRPARGQEEEFGLDAPKDLGPL
QFVKLRKHHSLVDDAWFCDRITVQGPGAGEEVAFPCYRWVQGDGVLCLPEGTARLAGDNA
LDVFQKHREKELKERRQIYCWATWKEGLPQTIAAGCEDDLPPNVRFHEEKRRDFEWTLKA
GALEMVLKRVYTLLSSWNHLEDFDNIFWGQKSTLAEQVRQHWQEDELFGYQFLNGANPML
LRRCTSLPSRLVLSSGMEALRAQLEKELENGSLFKADFTLLDGIPANVIRGEQQYLAAPL
VLLKMEPSGKLLPMVIQIQPPSHSCPTPPLFLPSDPPLAWLLAKCWVRNSDFQLHQLQYH
LLNTHLLAEVIAVATMRCLPGLHPVFKLLIPHIRYTMEINTRARTQLISDGGIFDKAVGT
GGGGHVHLLRRAMAQLTYRSLCPPHDLADRGLLGTPGAHYAHDALQLWEITARYVEGIVQ
LFYHGDDVVKEDPELQAWCREITEVGLCQAQDRGFPVSLQSQNQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAITWHLGRR
QPDMVPLGHHKEMYFSSPKAKAVLNQFQRDLENLEKAITARNEQLNLPYEYLRPSLIENS
VTI
NT seq 1992 nt   +upstreamnt  +downstreamnt
atgggccgctaccgcatccgggtggccaccggagactcgatcttcgccgggtcgctcaac
agcgtgcagctggggctggtcggggcgcgcggggagacggagctggagctgcagctgcgg
ccggcgcggggccaggaggaggagttcgggcttgacgctcccaaggacttggggccgctg
cagttcgtcaagctgcgcaaacaccactccctggtggacgacgcgtggttctgcgaccgc
atcacggtgcagggccctggagccggcgaggaggtcgccttcccctgctaccgctgggtg
cagggggacggcgtactgtgcctgcccgagggcaccgcccgcctggcaggagacaatgca
ctggacgtgttccagaagcatcgagaaaaggaactgaaagaaagacgtcagatatactgc
tgggccacctggaaggaagggttaccccagacaatagctgcaggctgtgaggatgaccta
cctccaaacgtgagattccatgaggagaagaggagagactttgagtggacactgaaggca
ggggctctggagatggtcctcaagcgtgtctacaccctcctgagctcctggaaccacctg
gaggattttgataacatcttctggggccagaagagcaccctggctgagcaggttcgccag
cactggcaggaggatgaactctttggctaccagttcctcaatggcgccaaccctatgctg
ttgagacgctgcacctctctgccctcccggctcgtgctgtcctcggggatggaggcgcta
cgggcccagctggaaaaagaactcgagaatggctccctgttcaaggccgatttcaccctc
ctggatggaattccggccaacgtgatccgcggagagcagcagtacctggctgcccccctc
gtcctgctgaagatggagcccagcgggaagctgctacccatggttatccagatccagcct
cccagccacagctgtcccacgccacccctgttcctgccctccgatcctccccttgcctgg
ctcctggccaagtgctgggtccgaaattccgatttccagctgcaccagctccagtatcat
ctgctgaacacccacctgctggctgaggtcattgccgtggccaccatgaggtgtctccca
gggctgcaccctgtcttcaagctcctgatcccacacatccgctacactatggaaatcaac
acgcgggcccggacccagctcatctcggacggaggtatattcgataaggcagtgggcacc
ggtggagggggccacgtgcacttgctccgccgggcgatggctcagctgacctaccgctcc
ctctgtccccctcacgatctggctgaccgcggcctgctgggaaccccaggggctcactat
gcccacgatgctttgcagctctgggagatcactgctcggtacgtggaggggattgtccag
ctcttctaccacggggacgatgtcgtcaaagaggaccctgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccaggaccgaggtttccctgtgtccctccag
tcccagaaccaactctgccatttccttaccatgtgcgtcttcacgtgcaccgctcagcac
ggggccatcaaccagggccagctggactggtacgcctgggtccctaatgccccctgcacg
atgcggatgcccccacccaccaccaaggaagacgtgacaatggccacagtgatgggctcg
ctacctgatgtccgacaggcctgtcttcaaatggccatcacatggcatctgggtcgccgc
cagccagacatggtgcctctggggcatcacaaagaaatgtatttctcaagccccaaggcc
aaggctgtactaaaccaattccaaagagatttggaaaacttggaaaaggctattacagcc
cgcaatgagcaacttaacctgccctatgaatacctgaggcccagcctcatagagaacagc
gttaccatctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (2)   
   Pfam (2)   
All databases (38)   

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