KEGG   Sus scrofa (pig): 396762
Entry
396762            CDS       T01009                                 
Symbol
FGFR2
Name
(RefSeq) fibroblast growth factor receptor 2 precursor
  KO
K05093  fibroblast growth factor receptor 2 [EC:2.7.10.1]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc01521  EGFR tyrosine kinase inhibitor resistance
ssc04010  MAPK signaling pathway
ssc04014  Ras signaling pathway
ssc04015  Rap1 signaling pathway
ssc04020  Calcium signaling pathway
ssc04144  Endocytosis
ssc04151  PI3K-Akt signaling pathway
ssc04550  Signaling pathways regulating pluripotency of stem cells
ssc04810  Regulation of actin cytoskeleton
ssc05200  Pathways in cancer
ssc05215  Prostate cancer
ssc05226  Gastric cancer
ssc05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    396762 (FGFR2)
   04014 Ras signaling pathway
    396762 (FGFR2)
   04015 Rap1 signaling pathway
    396762 (FGFR2)
   04020 Calcium signaling pathway
    396762 (FGFR2)
   04151 PI3K-Akt signaling pathway
    396762 (FGFR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    396762 (FGFR2)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    396762 (FGFR2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    396762 (FGFR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    396762 (FGFR2)
   05230 Central carbon metabolism in cancer
    396762 (FGFR2)
  09162 Cancer: specific types
   05226 Gastric cancer
    396762 (FGFR2)
   05215 Prostate cancer
    396762 (FGFR2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    396762 (FGFR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ssc01001]
    396762 (FGFR2)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ssc04090]
    396762 (FGFR2)
   00536 Glycosaminoglycan binding proteins [BR:ssc00536]
    396762 (FGFR2)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     396762 (FGFR2)
Protein kinases [BR:ssc01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   396762 (FGFR2)
CD molecules [BR:ssc04090]
 Proteins
  396762 (FGFR2)
Glycosaminoglycan binding proteins [BR:ssc00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   396762 (FGFR2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set Ig_5 ABC1 C2-set_2 V-set_CD47 DUF5527 Kinase-like Pkinase_fungal
Other DBs
NCBI-GeneID: 396762
NCBI-ProteinID: NP_001093394
Ensembl: ENSSSCG00000010698 ENSSSCG00000027367
Vega: OTTSUSG00000003528
UniProt: A5A754 A0A4X1SP68
Position
14:complement(131183095..131285001)
AA seq 822 aa
MVSWGRFICLVVVTMATLSLARPSFNLVEDTTVEPEEPPTKYQISQPEVYVAAPRESLEL
RCLLRDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTAARSVDSETVYF
MVNVTDAISSGDDEDDTDGSEDFVSENSNSKRAPYWTNTEKMEKRLHAVPAANTVKFRCP
AGGSPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENDYGSI
NHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSK
YGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK
QQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKTTTKKPDFSSQPAVHKLT
KRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRD
KLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMK
MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDVNRVPEEQMT
FKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKK
TTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEG
HRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEDYLDLSQPLEQY
SPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPPYPQRNGSVNT
NT seq 2469 nt   +upstreamnt  +downstreamnt
atggtcagctggggccgcttcatctgcctggttgtggtcaccatggcaaccttgtctctg
gcccggccctccttcaatttagttgaggataccacggtggagccggaagagccaccaacc
aaataccaaatctcccaaccagaagtttacgtggctgcgccccgggagtcgctagagttg
cgctgcctgttgcgagatgccgccgtgatcagttggactaaggatggggtacacttgggg
cccaacaataggacagtgcttattggggagtacttgcagataaaaggtgccacgcctagg
gactccggcctctatgcttgtaccgctgctaggagtgtagacagtgagactgtctacttc
atggtcaatgtcacagatgccatctcgtccggagatgacgaggacgacaccgatggctca
gaggattttgtcagtgagaacagtaacagcaagagagccccgtactggaccaacacagaa
aagatggaaaaacggctgcacgctgtccctgccgccaacactgtcaagttccgctgtcca
gctgggggtagtccaacaccaacgatgaggtggctgaaaaacgggaaggaatttaagcag
gaacatcgcattggaggctataaggtacgaaaccagcactggagcctcattatggaaagc
gtggttccatccgacaaaggaaattatacctgcgtggtggagaacgattacgggtccatc
aatcacacrtaccacctcgacgtcgttgagcgatcgccgcaccggcccatcctccaagcc
ggactgccggccaacgcctccaccgtggttgggggcgacgtggagtttgtctgcaaggtg
tacagtgatgcccagccccacatccagtggatcaaacacgtggaaaagaacggcagcaaa
tacgggcccgacgggctgccttacctcaaggttctgaagcactcagggataaatagttcc
aatgcagaagtgctggctctgttcaatgtgactgaggcggatgctggggagtatatttgt
aaggtctccaattatatagggcaggccaaccagtctgcctggctcactgtcctgccaaaa
cagcaagctcccgtgagagaaaaggagatcacagcttccccagactacctggagatagcc
atttactgcataggggtcttcctgatcgcctgcatggtggtgacggtcattctgtgccgg
atgaagaccaccaccaagaagccggacttcagcagccagccggcagtgcacaagctgacc
aagcgcatccccctgcggagacaggtaacagtttctgccgagtccagctcctccatgaac
tccaacaccccactggtgaggattacaactcgcctctcctccacagcagacacccccatg
ctggcgggggtctccgagtacgagctgccggaagatccaaagtgggagtttcccagagat
aagctgacgctgggcaaacccctgggagaaggttgctttgggcaagtggtcatggctgaa
gcggtgggaatcgacaaagagaagcccaaggaagcagtcactgtggccgtgaagatgttg
aaagatgatgccacagagaaagacctttctgatctggtgtcagagatggagatgatgaag
atgattggcaaacacaaaaatatcataaatctcctcggagcctgtactcaggatgggccg
ctctacgtcatagtcgagtacgcctcgaaaggcaacctccgagagtacctgcgcgcccgg
cggcctccggggatggagtactcgtacgacgtcaaccgcgtgcccgaggagcagatgacc
ttcaaggacttggtgtcctgcacctaccagctggcccggggcatggagtacttggcctcc
caaaaatgtatccatcgagatttagccgccagaaatgttttggtaacagaaaacaatgtg
atgaaaatagccgacttcggactggccagagatatcaacaatatagactattacaaaaag
accaccaatggccggcttccggtcaagtggatggctccagaggccctttttgatcgcgtg
tacacccaccagagtgatgtctggtccttcggggtgttaatgtgggagatcttcacgtta
gggggctcgccctacccagggattcccgtggaggaactttttaagctgctcaaagaagga
cacaggatggataagccagcaaactgcaccaacgaactgtatatgatgatgagagactgt
tggcatgcggtgccctcacagagacccaccttcaagcagttggtagaagacttggatcga
attctcacactcacgaccaatgaggactacttggacctcagtcagcctctcgaacagtat
tcacctagttaccctgacaccaggagttcttgctcttcgggagatgattctgttttctct
ccggaccccatgccttatgaaccctgccttcctccgtacccacagagaaacggcagtgtt
aacacatga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (13)   
   KEGG PATHWAY (13)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (2)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
Protein domain (14)   
   Pfam (14)   
All databases (63)   

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