KEGG   Sus scrofa (pig): 396875
Entry
396875            CDS       T01009                                 
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04020  Calcium signaling pathway
ssc04022  cGMP-PKG signaling pathway
ssc04024  cAMP signaling pathway
ssc04148  Efferocytosis
ssc04260  Cardiac muscle contraction
ssc04261  Adrenergic signaling in cardiomyocytes
ssc04380  Osteoclast differentiation
ssc04919  Thyroid hormone signaling pathway
ssc04972  Pancreatic secretion
ssc05010  Alzheimer disease
ssc05017  Spinocerebellar ataxia
ssc05022  Pathways of neurodegeneration - multiple diseases
ssc05410  Hypertrophic cardiomyopathy
ssc05412  Arrhythmogenic right ventricular cardiomyopathy
ssc05414  Dilated cardiomyopathy
ssc05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    396875 (ATP2A2)
   04024 cAMP signaling pathway
    396875 (ATP2A2)
   04022 cGMP-PKG signaling pathway
    396875 (ATP2A2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    396875 (ATP2A2)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    396875 (ATP2A2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    396875 (ATP2A2)
   04261 Adrenergic signaling in cardiomyocytes
    396875 (ATP2A2)
  09154 Digestive system
   04972 Pancreatic secretion
    396875 (ATP2A2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    396875 (ATP2A2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    396875 (ATP2A2)
   05017 Spinocerebellar ataxia
    396875 (ATP2A2)
   05022 Pathways of neurodegeneration - multiple diseases
    396875 (ATP2A2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    396875 (ATP2A2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    396875 (ATP2A2)
   05414 Dilated cardiomyopathy
    396875 (ATP2A2)
   05415 Diabetic cardiomyopathy
    396875 (ATP2A2)
Enzymes [BR:ssc01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     396875 (ATP2A2)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 396875
NCBI-ProteinID: NP_999030
UniProt: P11607 A0A480M6X9
Structure
Position
14:31674659..31744981
AA seq 1042 aa
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPMRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQREACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFEGVDCAVFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq 3129 nt   +upstreamnt  +downstreamnt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttaccggctgaagaagggaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctcgttagaattttattgttggcagcatgtatatcttttgttttggcttggtttgaagaa
ggcgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaaggaatgcagaaaatgccatcgaagcccttaag
gagtatgagcctgaaatgggcaaagtgtatcgacaggacaggaagagtgtacaacgaatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacgtccatcaaatctactactctaagagttgaccagtcaattctc
acaggtgagtctgtctctgtcatcaagcacaccgaccctgtccctgacccacgggctgtc
aaccaagataagaagaacatgctcttttctggtacaaacatagcagctggcaaagccatg
ggagtggtggtggcaactggagttaacactgaaattggcaagatccgggatgaaatggta
gcaacggaacaggagagaacacccctccagcagaaactagatgagtttggggaacagctt
tccaaagtcatctcccttatttgcattgcagtctggatcataaacattgggcacttcaat
gacccggttcatggaggctcctggatcagaggtgctatttattactttaaaattgcagtg
gccctggctgtagcagccattcctgaaggcctgcctgctgtcattaccacctgcctggct
cttggaactcgtagaatggcaaagaaaaatgccattgttcgaagtctcccttctgtggaa
acccttggttgcacttccgttatctgctcagacaagactggtacacttacaacaaaccag
atgtcagtctgcaggatgttcattctggacaaagttgaaggtgatacttgttccctgaat
gagtttaccataactggatcaacatatgctcctattggagaagtccataaagatgataaa
ccagtaaagtgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctctgt
aatgactctgctttggattacaatgaggcaaagggtgtgtatgaaaaagttggagaagct
acagagactgctctcacttgcctggtagagaagatgaatgtctttgatactgagttaaag
ggtctttctaaaatagaacgagcaaatgcctgcaactcggtcattaaacaattgatgaaa
aaggaatttactctagagttttcacgtgatagaaaatcaatgtcagtttattgtacacca
aacaaaccaagccggacatcgatgagcaaaatgtttgtgaagggtgctcccgaaggtgtc
attgacaggtgtacccacattcgagttggaagtactaaagtccccatgactcctggcgtc
aaacagaagatcatgtctgtcattcgggaatggggcagtggcagcgacacactgcgatgc
ctggctctggccactcatgacaacccgatgagaagagaagaaatgaaccttgaggattct
gccaactttattaaatacgagaccaatctgactttcgttggctgtgtgggcatgctggac
cctccaagaatcgaagtggcctcctctgtgaagctgtgccggcaggcaggcatccgggtc
attatgatcacaggcgacaacaagggtaccgctgtggccatctgccgtcgcattggcatc
tttgggcaggacgaggatgtgacgtcaaaggcttttacaggtcgggagtttgatgagctc
aatccttcagcccagagagaagcctgcctgaatgcccgctgtttcgctcgagttgaacct
tcccacaagtctaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggggacggtgtgaatgatgctcctgctctgaagaagtctgagatcggcattgccatgggc
tctggcaccgcggtggctaaaactgcctccgagatggtcctggctgatgacaacttctcc
accattgtggctgctgtggaggagggacgggcaatatacaacaacatgaagcagttcatt
cgctacctcatctcgtccaacgtgggagaagttgtctgtattttcctgacagcagccctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagatggc
ctgcctgccactgcactggggttcaatcctcctgatctggacattatgaacaaaccaccc
cggaacccaaaggaaccactgatcagtgggtggctctttttccgctacctggctattggc
tgttacgttggtgctgctactgtgggtgctgctgcgtggtggttcattgctgccgatggt
ggtccgagagtgaccttctaccagctgagtcatttcctacagtgtaaagaggacaaccca
gactttgagggagtggattgtgcagtctttgaatccccttacccaatgacaatggcgctg
tctgttctagtcaccatagagatgtgtaacgccctcaacagtttgtcggaaaaccagtcc
ctgctaaggatgccaccttgggagaacatttggctcgtgggctccatctgcctgtccatg
tcactccacttcctaatcctctatgtggaacccctgccacttatcttccagatcacaccg
ctgaatttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggat
gagaccctcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgtaccgatgggatttcctggccctttgtgctg
ctcataatgccgctggtgatctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (12)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (4)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (68)   

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