KEGG   Sus scrofa (pig): 397048
Entry
397048            CDS       T01009                                 
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
  KO
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00140  Steroid hormone biosynthesis
ssc01100  Metabolic pathways
ssc05215  Prostate cancer
Module
ssc_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    397048 (SRD5A2)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    397048 (SRD5A2)
Enzymes [BR:ssc01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     397048 (SRD5A2)
SSDB
Motif
Pfam: Steroid_dh DUF1295 PEMT DUF6832
Other DBs
NCBI-GeneID: 397048
NCBI-ProteinID: NP_999153
Ensembl: ENSSSCG00000008521
UniProt: O18765
Position
3:107840200..107918351
AA seq 254 aa
MPVRCQQSPVLAGSATLAALGALALYFAEPSGYGKYTESLTPAAIRLPARAAWFLQELPS
FVVPAGILAGQPRSLFGPPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVVFLFRGFVFCM
GNGLLQGYYLVYCAEYPAEWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEVIYKI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYVKMFE
DYPKSRKALIPFIF
NT seq 765 nt   +upstreamnt  +downstreamnt
atgcctgttcgctgccagcagagcccggtgctggcgggcagcgccactttggctgccctg
ggggcactggccctgtacttcgcggagccctctggctacgggaagtacacggagagcctg
acgcccgcggctatccgcctgccagcccgtgccgcctggttcctgcaggagctgccctcc
ttcgtggtgcccgcggggatcctcgccgggcagccccgttctctcttcggcccgcctgcg
actgtgcttctgggcctcttctgcgcacattacttccacaggacatttgtttactcactg
ctcactagagggaggccttttccagttgtattccttttcagaggctttgtcttctgcatg
ggaaatggactccttcaaggctactatctggtttactgtgccgaataccctgctgagtgg
tacacagacatacggtttagcctaggtgtgttcttatttattttgggcatgggaatcaac
attcacagcgactatatattgcgccagctcaggaagcctggagaagtcatctataagatt
ccacaaggtggcttgttcacgtacgtttctggagccaatttccttggtgagatcattgaa
tggatcggctatgccttggccacttggtcccttccagcacttgcatttgcatttttctcg
ctttgtttccttgggctgcgagcttttcaccatcataggttctacgtcaagatgtttgag
gactaccccaagtctcgaaaagcccttattccatttatcttttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (45)   

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