KEGG   Sus scrofa (pig): 397117
Entry
397117            CDS       T01009                                 
Symbol
GSTO1
Name
(RefSeq) glutathione S-transferase omega-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00480  Glutathione metabolism
ssc00980  Metabolism of xenobiotics by cytochrome P450
ssc00982  Drug metabolism - cytochrome P450
ssc00983  Drug metabolism - other enzymes
ssc01100  Metabolic pathways
ssc01524  Platinum drug resistance
ssc05200  Pathways in cancer
ssc05204  Chemical carcinogenesis - DNA adducts
ssc05207  Chemical carcinogenesis - receptor activation
ssc05208  Chemical carcinogenesis - reactive oxygen species
ssc05225  Hepatocellular carcinoma
ssc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    397117 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    397117 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    397117 (GSTO1)
   00983 Drug metabolism - other enzymes
    397117 (GSTO1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    397117 (GSTO1)
   05204 Chemical carcinogenesis - DNA adducts
    397117 (GSTO1)
   05207 Chemical carcinogenesis - receptor activation
    397117 (GSTO1)
   05208 Chemical carcinogenesis - reactive oxygen species
    397117 (GSTO1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    397117 (GSTO1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    397117 (GSTO1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    397117 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ssc02000]
    397117 (GSTO1)
Enzymes [BR:ssc01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     397117 (GSTO1)
Transporters [BR:ssc02000]
 Other transporters
  Pores ion channels [TC:1]
   397117 (GSTO1)
SSDB
Motif
Pfam: GST_N_2 GST_N_3 GST_N GST_C GST_C_3 GST_C_2 Glutaredoxin GST_C_5
Other DBs
NCBI-GeneID: 397117
NCBI-ProteinID: NP_999215
Ensembl: ENSSSCG00000022351
UniProt: Q9N1F5 A0A481BZ29
Position
14:115206434..115216624
AA seq 241 aa
MSGGSARSLGKGSAPPGPVPEGLIRVYSMRFCPFAQRTLLVLNAKGIRHQVININLKNKP
EWFFQKNPSGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMVFELS
SKVPPLLIRFIRRENEADCSGLKEELRKEFSKLEEVLTKKKTTYFGGSSLSMIDYLIWPW
FERLEALELNECIDHTPKLKLWMAAMMKDPAVSALHIEPRDLRAFNDLYLQNSPEACDYG
L
NT seq 726 nt   +upstreamnt  +downstreamnt
atgtctggaggatcagccagaagcctggggaagggaagtgcgcccccggggccggtcccc
gagggcctgatccgtgtctacagcatgagattctgtcctttcgcccagaggactctcctg
gtcctgaatgccaagggaatccggcatcaagtcatcaacatcaacctgaaaaataagcct
gagtggttcttccagaagaatccctcaggtctggtgccagttctggaaaacagtcagggt
caactgatctatgaatctgccatcacttgtgagtacctggatgaagcatatccagggaag
aagctgttgccagatgacccctatgagaaagcttgccaaaagatggtctttgagttgtct
tctaaggtaccgcctttgctaatacgctttattagaagggaaaatgaggcagactgctct
ggcctaaaagaagaattacgtaaagaattcagcaagctagaggaggttctgaccaaaaag
aagacaacatactttggtggaagttctctttctatgattgattacctcatctggccctgg
tttgaaaggctggaagccctggagttaaatgagtgtatagaccacactccaaaacttaag
ctctggatggcagccatgatgaaagatccggcggtatcagccctccacattgaaccgaga
gaccttcgagctttcaatgacctctacttgcagaacagcccagaggcctgtgactatggg
ctctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   PROTHERM (2)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
Protein domain (8)   
   Pfam (8)   
All databases (118)   

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