KEGG   Sus scrofa (pig): 397241
Entry
397241            CDS       T01009                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04010  MAPK signaling pathway
ssc04020  Calcium signaling pathway
ssc04022  cGMP-PKG signaling pathway
ssc04114  Oocyte meiosis
ssc04218  Cellular senescence
ssc04310  Wnt signaling pathway
ssc04360  Axon guidance
ssc04370  VEGF signaling pathway
ssc04380  Osteoclast differentiation
ssc04625  C-type lectin receptor signaling pathway
ssc04650  Natural killer cell mediated cytotoxicity
ssc04658  Th1 and Th2 cell differentiation
ssc04659  Th17 cell differentiation
ssc04660  T cell receptor signaling pathway
ssc04662  B cell receptor signaling pathway
ssc04720  Long-term potentiation
ssc04724  Glutamatergic synapse
ssc04728  Dopaminergic synapse
ssc04921  Oxytocin signaling pathway
ssc04922  Glucagon signaling pathway
ssc04924  Renin secretion
ssc05010  Alzheimer disease
ssc05014  Amyotrophic lateral sclerosis
ssc05020  Prion disease
ssc05022  Pathways of neurodegeneration - multiple diseases
ssc05031  Amphetamine addiction
ssc05152  Tuberculosis
ssc05163  Human cytomegalovirus infection
ssc05166  Human T-cell leukemia virus 1 infection
ssc05167  Kaposi sarcoma-associated herpesvirus infection
ssc05170  Human immunodeficiency virus 1 infection
ssc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ssc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    397241 (PPP3CA)
   04310 Wnt signaling pathway
    397241 (PPP3CA)
   04370 VEGF signaling pathway
    397241 (PPP3CA)
   04020 Calcium signaling pathway
    397241 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    397241 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    397241 (PPP3CA)
   04218 Cellular senescence
    397241 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    397241 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    397241 (PPP3CA)
   04660 T cell receptor signaling pathway
    397241 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    397241 (PPP3CA)
   04659 Th17 cell differentiation
    397241 (PPP3CA)
   04662 B cell receptor signaling pathway
    397241 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    397241 (PPP3CA)
   04921 Oxytocin signaling pathway
    397241 (PPP3CA)
   04924 Renin secretion
    397241 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    397241 (PPP3CA)
   04728 Dopaminergic synapse
    397241 (PPP3CA)
   04720 Long-term potentiation
    397241 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    397241 (PPP3CA)
   04380 Osteoclast differentiation
    397241 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    397241 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    397241 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    397241 (PPP3CA)
   05163 Human cytomegalovirus infection
    397241 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    397241 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    397241 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    397241 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    397241 (PPP3CA)
   05020 Prion disease
    397241 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    397241 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    397241 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    397241 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ssc01009]
    397241 (PPP3CA)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     397241 (PPP3CA)
Protein phosphatases and associated proteins [BR:ssc01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     397241 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 397241
NCBI-ProteinID: NP_999293
UniProt: Q95MZ3 A0A8D1SEU2
Position
8:119429181..119754615
AA seq 511 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEENV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSEHVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM
PSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1536 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacagccaaagaagtgtttgataacgatgggaaa
cctcgtgtggatatcttaaaggcacatctcatgaaggagggaaggctggaagagaatgtt
gcattgagaataataacagagggggcttcaattcttcgacaggaaaagaatttgctggat
attgatgcaccagtcacagtttgtggggacatccatggacaattctttgacttgatgaaa
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtacttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaattaagtattcagaacacgtatatgatgcctgcatggat
gcctttgactgcctcccactggctgccctgatgaaccagcagttcctgtgtgtccacggt
ggtttgtctccagagattaacactttagatgatatcagaaaattagaccgattcaaggaa
ccacctgcttatggacctatgtgtgacatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatactccgagcc
catgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaaatatgagaacaatgtcatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaacttcatggatgttttcacctggtccctgccatttgttggggagaaa
gtgactgagatgctggtgaatgtcctcaatatttgctcagatgatgaactagggtcagaa
gaagatggatttgatggagcaacagccgcagcccggaaggaggtgataaggaacaagatt
cgggcgatcggcaagatggccagagtgttctcggttctcagagaagagagtgagagtgtg
ctgacgctgaaaggcctgacgcccacaggcatgctccccagcggagtgctttctggaggg
aagcaaaccctgcaaagcgctatcaaaggattttcaccacaacataagatcactagcttc
gaggaggccaagggcttagaccgaattaacgagaggatgccacctcgcagagatgccatg
ccctccgacgccaaccttaactccatcaacaaggctctcgcctcagagactaacggcaca
gacagcaatggcagtaatagcagcaatatccagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (33)   
   KEGG PATHWAY (33)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   RefSeq(pep) (6)   
DNA sequence (22)   
   RefSeq(nuc) (6)   
   GenBank (8)   
   EMBL (8)   
Protein domain (1)   
   Pfam (1)   
All databases (98)   

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