KEGG   Sus scrofa (pig): 397324
Entry
397324            CDS       T01009                                 
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00061  Fatty acid biosynthesis
ssc00620  Pyruvate metabolism
ssc00640  Propanoate metabolism
ssc01100  Metabolic pathways
ssc01212  Fatty acid metabolism
ssc04152  AMPK signaling pathway
ssc04910  Insulin signaling pathway
ssc04922  Glucagon signaling pathway
ssc04936  Alcoholic liver disease
Module
ssc_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    397324 (ACACA)
   00640 Propanoate metabolism
    397324 (ACACA)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    397324 (ACACA)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    397324 (ACACA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    397324 (ACACA)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    397324 (ACACA)
   04922 Glucagon signaling pathway
    397324 (ACACA)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    397324 (ACACA)
Enzymes [BR:ssc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     397324 (ACACA)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     397324 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     397324 (ACACA)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 MetallophosN
Other DBs
NCBI-GeneID: 397324
NCBI-ProteinID: NP_001107741
Ensembl: ENSSSCG00000017694
UniProt: B0LJD0
Position
12:complement(38580916..38875067)
AA seq 2346 aa
MDEPSPLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLS
DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWHENDFSKRILNVPQDLYEKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLARMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGVPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LSAHTLLNTVDVELIYGGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQA
YLPPPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPEGRDIIVI
GNDITYRIGSFGPQEDVLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS
GMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSTSQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVCSSVPLLNSKDPID
RVIEFVPTKAPYDPRWMLAGRAHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQMLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAE
RKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST
MDSPST
NT seq 7041 nt   +upstreamnt  +downstreamnt
atggatgaaccgtctcccttggctaaacctctggagttgaaccagcactcccgcttcata
attggttctgtgtctgaagataactcagaggatgagattagcaacctggtgaagctggac
ctgctggaggagaaggagggctctctgtcaccagcttctgtcagctcagatacgctctct
gacttggggatttctagcctacaggatggcttggccttacacatgaggtccagcatgtct
ggcttgcacctagtaaagcaaggtcgagaccgaaagaaaatagactctcagcgagatttc
actgtagcttctccagcagaatttgttactcgttttggtgggaataaagtgattgagaag
gttctcattgccaacaatggcatcgcagcagtgaaatgcatgcggtctatccgccggtgg
tcttatgagatgtttcgaaatgagcgtgcaatccggtttgttgtcatggtcacacccgaa
gacctgaaagccaacgctgaatacattaagatggcagatcactatgtgccagtgccagga
ggaccaaacaacaacaactatgcaaatgtggaattaattcttgatattgctaaaaggatc
ccagtgcaagcagtatgggctggctggggccatgcttctgagaatcccaagctcccagaa
cttcttttgaaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggcttta
ggggataagattgcatcatcaatagtggcccaaactgcaggtatcccaactcttccatgg
agtggcagtggtcttcgtgtggattggcatgaaaatgatttttccaaacgtatcttaaat
gtcccccaggacctgtatgaaaaaggttatgtgaaggatgtggatgatgggctgaaggca
gcagaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaggga
atcagaaaggtcaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaa
gtccccggatctcctatctttgtgatgagactagccaaacagtcccgtcatctggaggtg
cagatcttagcagatcagtacggcaatgctatatctttgtttggtcgggattgctctgta
cagcgcaggcatcagaagattattgaagaggcacctgctgctattgctactccagcagta
tttgaacatatggaacagtgtgcggtgaaactggccagaatggttggttatgtgagtgct
gggacggtggagtacctctacagccaggatggcagcttctactttctggaactgaaccct
cggctacaggtggagcacccttgtacagagatggtggctgatgtcaacctccccgcagca
cagctgcagattgccatgggggtccctctgtatagaatcaaggacatccgaatgatgtat
ggggtatctccctggggcgatgcccccatcgattttgaaaattctgctcatgttccttgc
ccaaggggccatgttattgctgctcggatcactagtgaaaatccagatgagggtttcaag
ccaagctcaggaacggttcaggaactgaatttccgcagcaataagaatgtttggggttat
ttcagcgttgctgctgcaggcggacttcatgaatttgctgattctcagtttggtcactgc
ttttcctggggagaaaaccgagaggaagcaatttcaaacatggtggtggctttgaaggag
ctatctattcggggtgactttcgcactacagttgaatatctgatcaaattgctggagact
gaaagctttcagctgaatagaattgacactggctggctggacagactgatagcagaaaaa
gtacaggcagagcgtcctgacaccatgttgggagtggtgtgtggggctctccacgtggca
gatgtgagccttcggaacagcatctccaacttccttcactccttggagaggggtcaagtc
ctttctgctcatacacttctgaacacagtagacgttgaacttatctatgggggagtcaag
tatgtactgaaggtgactcgacagtcccctaactcctacgtggtgatcatgaatggctcg
tgtgtggaagtagacgtacatcggctgagtgacggaggcctgctcctgtcctacgatggc
agcagttacaccacgtacatgaaggaggaggtggatagatatcgcatcacaatcggcaat
aaaacctgtgtgtttgagaaggaaaatgacccttcagtaatgcgctcaccttctgctggg
aagttaatccagtacattgtggaggatggaggtcatgtgtttgctggccagtgctacgct
gagatcgaggtgatgaagatggtaatgaccttaacagctgcagagtctggctgtatccat
tatgtcaagcggcccggagcagctcttgaccctggctgtgtcatagccaaaatgcagttg
gacaaccccagcaaggtccagcaggctgagcttcacacaggcagtctgccgcagatccag
agcacagccctcaggggcgagaagctccaccgagtgttccactacgtcctggataatcta
gtcaatgtgatgaatggatactgccttccagatcccttcttcagcagtagggtaaaagac
tgggttgaacggttgatgaagaccctcagagatccctccttgcctctcctagaattgcaa
gatatcatgaccagtgtttctggcagaatcccccccaacgtggagaagtctatcaagaag
gaaatggctcaatatgcgagcaacatcacatcagtcctctgtcagtttcccagccagcag
attgccaacattctagatagccatgcagctacgttgaaccggaaatctgaacgggaagtc
ttcttcatgaacactcagagcatcgtccagctggtgcagaggtaccgaagcggcatccga
ggccacatgaaggctgtggtgatggatctgctgcggcaatacctgcgagtggagacacag
ttccagaacggtcactatgacaaatgcgtgtttgcccttcgggaggagaacaagagtgac
atgaacactgtcctgaactacatcttctctcacgctcaagtcaccaagaagaatctgctg
gtcacaatgcttatcgatcagttgtgtggccgggaccccactctcaccgacgagctcctg
aacatcctcactgagctgactcagctcagcaagaccaccaacgcgaaagtggccctccgc
gcacgccaggttcttattgcctcccatttgccatcatatgagcttcgccataaccaagta
gagtctatcttcctatcggctattgacatgtatggacatcagttttgcattgagaacctg
cagaaactcatcttgtctgaaacatctattttcgatgtcctaccaaacttcttctatcac
agcaaccaggtggtgaggatggcagcgctggaggtgtatgtgcgaagggcttatattgct
tatgaacttaacagtgtacaacaccgccagcttaaggacaacacttgtgtggtggaattc
cagttcatgctgcccacatctcatccaaacagagggaacatccccacgctaaacagaatg
tccttctcctccaacctcaaccactatggcatgactcatgtagccagtgtcagcgacgtg
ctgttggacaacgcattcactccaccgtgtcagcggatgggcggaatggtctctttccgg
acttttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgattcccca
ccccaaagccccacattccccgaggcaggtcacacgtctctgtacgacgaagacaaggtc
cccagggatgaaccaattcacattctgaatgtggctatcaaaactgactgtgacattgag
gacgacaggctggcagctatgttccgagagtttacccagcaaaataaagctacgctggtt
gagcatgggatccggcgccttactttcctggttgcacaaaaggatttcagaaaacaggtc
aactatgaagtggatcagagatttcatagagaattccctaaatttttcacattccgagca
agggataagtttgaggaagatcgtatctatcgtcacctggagcctgccctagctttccag
ttagagctgaaccggatgagaaattttgacctcactgccatcccatgtgctaatcacaag
atgcacctgtaccttggggcagccaaggtggaagtgggcacagaagtgacagactacagg
ttctttgttcgtgcaatcatcagacattctgatctggtcaccaaggaagcctcctttgag
tatctacagaatgaaggggaacggctgctcctagaagctatggatgagttggaagtcgct
tttaacaatacaaatgtccggaccgactgcaaccacatcttcctaaactttgtgcctaca
gtcatcatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctatgga
agccggctgtggaaattacgcgtcctccaggcagaactgaaaatcaacattcgcctgaca
ccaactgggaaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttg
gatatcagcctgtacaaggaagtgactgactccaggacagcacagatcatgtttcaggca
tatggagacaaacagggaccattacatggaatgttaatcaacactccatatgtgaccaaa
gacctacttcaatcaaagaggttccaggcacagtccttagggacaacgtacatatatgat
atcccagagatgtttcggcagtccctgatcaaactctgggagtctatgtccactcaagca
tacctcccaccgccccctctgccttctgacatgctgacgtacactgagctcgtgttggat
gatcaaggtcagctggtccacatgaacaggcttccaggaggaaatgagattggcatggta
gcttggaaaatgtcccttaaaagtccggaatatccagaaggccgagatatcattgttatt
ggcaatgacatcacataccgaattggttcctttggaccccaggaggatgtgctatttctc
agagcgtctgagcttgccagggcagagggcatcccacgcatctatgtagctgccaacagt
ggagcgagaattgggctggcagaggaaattcgtcatatgtttcacgtggcctgggtagat
cctgaagatccttacaagggatacaaatacttatatctgacccctcaagactataagaga
gtcagtgctctcaactctgtccattgtgagcatgtggaggatgaaggagaatccaggtac
aagattaccgatatcattgggaaggaagagggccttggagcagagaaccttcgaggttct
ggaatgattgctggagaatcctcattggcttataatgagatcatcaccattagcctggtt
acctgccgggccattgggattggggcttaccttgtccgactgggacagagaaccatccag
gttgaaaattctcacttaatcctgacaggagccggggccctcaacaaagttctcgggagg
gaggtgtacacctccactagccagctcgggggcatccagatcatgcacaacaacggggtc
acccacagcaccgtctgtgatgactttgaaggggtgttcactgtcctgcactggctgtct
tacatgcccaagagcgtatgcagttcagttcctctcttgaattccaaggatcctatagac
agagtcatcgagtttgttcccacgaaggctccgtatgatcctcgatggatgctggcaggc
cgtgctcacccaacccagaaaggtcaatggttgagtggattttttgactatggctctttc
tcagagatcatgcaaccctgggcgcagaccgtggtggtcggcagagctaggctaggagga
atacccgtgggagtagttgccgtagaaacccgcacagtggaactaagtatcccagctgat
cctgcaaacctggattctgaagccaagataatccagcaggccggccaggtttggtttcca
gactctgcgtttaagacctatcaggccatcaaggacttcaaccgcgaagggctgcctcta
atggtctttgccaactggagaggcttctccggggggatgaaagatatgtacgaccaaatg
ctgaagttcggcgcttacatcgtggacggcttacgggagtgctcacagccggtgatggtc
tatatccctcctcaggccgagcttcggggtggctcctgggtcgtgattgaccccaccatc
aacccgcggcacatggagatgtatgctgaccgcgagagcaggggatccgttctggaacca
gaagggaccgtagaaatcaaattccgcagaaaggatctggtgaaaacgatgcgtcgggtg
gacccagtctacatccacttggccgagcgattgggcaccccagagctcagcacggctgag
cggaaggagctggagagcaagctgaaggagcgggaggagttcctcctccccatttaccat
caggtagccgtgcagtttgctgacttgcacgacacaccgggccggatgcaggagaagggg
gttattaacgacatcctggattggaaaacatcccgtacatttttctactggcggctgagg
cgtctcttgctggaggacctggtcaagaagaaaatccacaatgccaaccccgagctgacc
gatggccagatccaggccatgttaaggcgctggtttgtggaggtggaaggaacagtgaag
gcctacgtttgggacaataacaaggacctggtggagtggctggagaaacagctgacggag
gaagacggtgttcgctcagtcatagaggaaaacatcaaatacatcagcagagactacgtc
ctcaagcagatccgcagcttggtccaggccaatccggaggtcgccatggattccatcgtg
cacatgacccagcacatctcacccactcagcgagcagaagtcgtccggatcctctccacg
atggactcgccttccacgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (9)   
   KEGG MODULE (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   RefSeq(pep) (12)   
DNA sequence (22)   
   RefSeq(nuc) (12)   
   GenBank (5)   
   EMBL (5)   
Protein domain (11)   
   Pfam (11)   
All databases (87)   

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