KEGG   Sus scrofa (pig): 397561
Entry
397561            CDS       T01009                                 
Symbol
FASN
Name
(RefSeq) fatty acid synthase
  KO
K00665  fatty acid synthase, animal type [EC:2.3.1.85]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00061  Fatty acid biosynthesis
ssc01100  Metabolic pathways
ssc01212  Fatty acid metabolism
ssc04152  AMPK signaling pathway
ssc04910  Insulin signaling pathway
ssc04936  Alcoholic liver disease
Module
ssc_M00082  Fatty acid biosynthesis, initiation
ssc_M00083  Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    397561 (FASN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    397561 (FASN)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    397561 (FASN)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    397561 (FASN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:ssc01004]
    397561 (FASN)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ssc04147]
    397561 (FASN)
Enzymes [BR:ssc01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.85  fatty-acid synthase system
     397561 (FASN)
Lipid biosynthesis proteins [BR:ssc01004]
 Fatty acid synthase
  Animal type
   397561 (FASN)
Exosome [BR:ssc04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   397561 (FASN)
  Exosomal proteins of breast milk
   397561 (FASN)
  Exosomal proteins of colorectal cancer cells
   397561 (FASN)
  Exosomal proteins of bladder cancer cells
   397561 (FASN)
SSDB
Motif
Pfam: Acyl_transf_1 ketoacyl-synt KR Thioesterase Ketoacyl-synt_C KAsynt_C_assoc FAS_pseudo-KR ADH_zinc_N_2 ADH_zinc_N PKS_DH_N PP-binding Methyltransf_12 Methyltransf_23 adh_short Methyltransf_31 Methyltransf_11 Thiolase_N Methyltransf_25 PS-DH
Other DBs
NCBI-GeneID: 397561
NCBI-ProteinID: NP_001093400
Ensembl: ENSSSCG00000029944
UniProt: A5YV76
Structure
Position
12:922405..937560
AA seq 2512 aa
MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTADDRRWKAGLYGLPRRMGKLKDLSRF
DASFFGVHSKQANTMDPQLRMLLEVTYEAIVDGGINPASLRGTSTGVWVGVSSSDASEAL
SRDPETLVGYSMIGCQRAMMANRLSFFFDFKGPSITIDTACSSSLLALQSAYQAIRGGEC
SAAVVGGLNVLLKPNSSLQFMKLGMLSQDGTCRSFDAEGTGYCRAEAVVAVLLTKKSLAR
RVYATILNAGTNTDGSKEQGVTFPSGDVQEQLIRSLYAPAGPDPESLEYIEAHGTGTKVG
DPQELNGIVNALCATRREPLLIGSTKSNMGHPEPASGVAALIKVLLSLEHGVWAPNLHYH
TPNPEIPALQDGRLQVVDRPLPIRGGNVGINSFGFGGSNVHVILQPNSRPAPPPAQHAAL
PRLLQASGRTLEAVQTLLEQGLRHSRDLAFVGMLNEIAAVSPVAMPFRGYAVLGGEAGSQ
EVQQVPGSKRPVWFICSGMGAQWQGMGLSLMRLDRFRDSILRSDQALKPLGLRVSDLLLS
TDEAVLDDIVSSFVSLTSIQIALIDLLTSLGLQPDGIIGHSLGEVACGYADGCLTQEEAV
LSSYWRGYCIKEANVLPGAMAAVGLSWEECKQRCPPGIVPACHNSKDTVTISGPQAAMSE
FLQQLKREDVFVKEVRTGGIAFHSYFMESIAPTLLRQLRKVILDPKPRSKRWLSTSIPEA
QWQGSLARTFSAEYSVNNLVSPVLFQEALQHVPAHAVVVEIAPHALLQAVLKRSLESSCT
IIPLMKKDHRDNLEFFLSNVGRLHLAGVSVNPNGLFPPVEFPAPRGTPLISPHXKWDHSQ
AWDVPSAADFPSGSSCSSVAVYKFDVSPESPDHYLVDHCIDGRVLFPGTGYLWLTWKTLA
RALSQNLEETPVVFEDVTLHQATILPKTGTVSLEVRLLEASHAFEVSDSNGSLIASGKVY
QWESPDPKLFDTRAAVDPADSTAEFRLSQGDVYKDLRLRGYDYGPFFQLVLESDLEGNRG
RLQWNDSWVSFLDAMLHMSILAPGQLGLYLPTRFTSIRIDPVTHRQKLYTLQDTTQAADV
VVDRNLNTVVAGGALFLGAHSSVAPRRPQEHLKPILEKFCFTPHVESGCLAGNTALQEEL
QLCRGLAQALQTKVAQQGLKMVVPGLDGAQAPREAPQQSLPRLLAAACQLQLNGNLQLEL
GQVLAQERPLLCDDPLLSGLLDAPALKACVDTALENMASPKMKVVEVLAGDGQLYSRIPA
LLNTQPVMDLDYTATDRNPQALEAAQAKLEQLHVTQGQWDPANPAPGSLGKADLLVCNCA
LATLGDPAVAVGNMAATLKEGGFLLLHTLLAGHPLGEMVGFLTSPEQGGRHLLSQDQWES
LFAGASLHLVALKRSFYGSVLFLCRQQTPQDSPVFLSVEDTSFRWVDSLKDILADASSRP
VWLMAVGCSTSGVVGMVNCLRKEPGGHRIRCVLVSNLSSTSPAPEMHPSSSELQKVLQGD
LVMNVYRDGAWGAFRHFPLEQDRPEKQTEHAFVNVLSRGDLSSIRWVCSPLHYALPASCQ
DRLCSVYYTSLNFRDVMLATGKLSPDSIPGKWLTRDCMLGMEFSGRDASGRRVMGMVPAE
GLATSVLLLQHATWEVPSTWTLEEAASVPIVYTTAYYSLVVRGRMQPGESVLIHSGSGGV
GQAAIAIALSRGCRVFTTVGSAEKRAYLQARFPQLDETCFANSRDTSFEQHVLRHTAGKG
VDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHALGMAVFLKNVTFHGILLDSLF
EEGGATWQEVSELLKAGIQEGVVQPLKCTVFPRTKVEAAFRYMAQGKHIGKVVIQVREEE
QGPAPRGLPPIALTGLSKTFCPPHKSYVITGGLGGFGLQLAQWLRLRGAQKLVLTSRSGI
RTGYQARQVREWRRQGVQVLVSTSNASSLDGARSLITEATQLGPVGGVFNLAMVLRDAVL
ENQTPEFFQDVSKPKYSGTANLDRVTREACPELDYFVIFSSVSCGRGNAGQANYGFANSA
MERICEKRRHDGLPGLAVQWGAIGDVGVVLETMGTNDTVIGGTLPQRIASCLEVLDLFLS
QPHPVLSSFVLAEKKAAAPRDGSSQKDLVKAVAHILGIRDVASINPDSTLVDLGLDSLMG
VEVRQILEREHDLVLSMREVRQLSLRKLQELSSKTSTDADPATPTSHEDSPVRQQATLNL
STLLVNPEGPTLTRLNSVQSAERPLFLVHPIEGSITVFHGLAAKLSIPTYGLQCTGAAPL
DSIQSLASYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQSATPGNHSLFLFDG
SHTFVLAYTQSVRAKMTPGCEAEAEAKAMYFFVQQFTDMEQGKVLEALIPLQGLEARVAA
TVDLITQSHAGLDRHALSFAARSFYQKLRAAENYWPQATYHGNVTLLRAKTGGAYGEDLG
ADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESILSIIHSCLAEPRVSVREG
NT seq 7539 nt   +upstreamnt  +downstreamnt
atggaggaggtggtgatcgccggcatgtccgggaagctgcccgagtcggagaacctggag
gagttctgggccaacctcatcggcggtgtggacatggtgacggccgacgacaggcggtgg
aaggcggggctgtacggcctgccccggcggatgggcaagctgaaggacctgtcccgcttc
gacgcctccttcttcggggtccactccaagcaggcgaacacgatggacccccagctgcgg
atgctgctggaggtcacctacgaggccattgtggacggaggcatcaaccctgcttccctt
cgtggcacgagcaccggtgtctgggtgggtgtgagcagttctgatgcctcagaggctctg
agccgagaccccgagaccctcgtgggctacagcatgataggctgccagcgcgccatgatg
gccaaccggctctccttcttctttgacttcaaggggcccagcatcaccatagacacggcc
tgctcctccagcctgctggctctgcagtccgcctaccaggccattcgcggaggggagtgc
tctgcggccgtcgtgggcggcctcaacgtcctgctgaagcctaactcctcgctgcaattc
atgaagctgggcatgctcagccaggacggcacctgcaggtccttcgatgccgaagggacc
ggctattgccgtgcggaggccgtggtggcggtcttgctgaccaagaagtccctggcccga
cgggtatacgccaccatcctcaatgcgggcacgaacacagacggttccaaggagcaaggt
gtgaccttcccctcgggagacgtgcaggagcagctcatccgctccctgtacgcgccagcc
gggccggaccccgagtccctggagtacatcgaagcccacggcaccggcaccaaggtgggc
gacccccaggagctgaacggcatcgtgaatgccctgtgtgccacccgccgggagcccctg
ttgatcggatccaccaagtcgaacatgggacacccggagcctgcctcgggggtcgcggcg
ctgatcaaggtgctgctgtcgttggagcatggggtctgggccccgaatctgcactaccac
accccgaaccccgagatcccagcattgcaggacgggcggctacaggtggtggaccggccc
ctgcccatccgtgggggcaacgtgggcataaactccttcggcttcggcggctccaacgtg
cacgtcatccttcagcccaactcccgccccgccccaccgcccgcccagcatgccgcgctg
ccccgtctgctgcaggccagcgggcgcaccctcgaggccgtgcagaccctgctggagcag
ggcctccggcacagccgagacctggcctttgtgggcatgctcaacgagatcgcggctgtc
tccccggtcgccatgcccttccgcggctacgccgtgctgggcggcgaggccggcagccag
gaggtgcagcaggtgccaggcagcaagcgcccggtctggttcatctgctcagggatgggc
gcacagtggcaggggatggggctgagcctcatgcgcctggaccgcttccgcgactccatc
ctgcgctcggaccaggccttgaagcctctggggctgcgggtgtccgacctgctgctgagc
acggacgaggccgtcctcgacgacatcgtctcttccttcgtgagcctcacctccatccag
atcgccctcatagacctgctgacctccttgggcctgcagcctgacggcatcatcgggcac
tccctgggcgaggtggcctgcggctatgccgacggctgcctgacccaggaggaggctgtg
ctctccagctactggaggggctattgcatcaaggaggccaacgtcctgccaggggccatg
gcagccgtgggcttgtcctgggaagagtgtaagcagcgctgcccccctggcatcgtgccc
gcctgccacaactccaaagacacggtgaccatctcgggacctcaggccgctatgtccgag
ttcctgcagcagctgaagcgggaggacgtgtttgtcaaggaggtgcggacgggcggcatc
gccttccactcctacttcatggagtccatcgcccccacgctgctgcgccagctcaggaag
gtgatcctggatccgaagccccgctccaagcgctggctcagcacctccatccctgaggcc
cagtggcagggcagcctggcccgcaccttctcggccgagtacagcgtcaacaacctggtg
agcccggtgctgttccaggaggcgctgcagcacgtgcccgcgcacgccgtggtggtggag
atcgccccgcacgccctgctgcaggccgtkctgaagagaagcctcgagtccagctgcacc
atcatcccgctgatgaagaaggaccacagggacaacctggagttcttcctcagcaacgtg
ggcaggctccacctggcgggcgtcagcgtcaaccccaacggtctgttcccacccgtggag
ttccctgctccccgggggactcccctcatctccccgcacawcaagtgggaccacagccag
gcctgggatgtgccctccgcggccgacttccccagcggctccagctgctcctctgtcgcc
gtctataagttcgacgtcagcccggagtccccggatcactaccttgtggatcactgcata
gacggccgggtccttttccctggcactggctacctgtggctgacctggaagacgctggca
cgagccctgagccagaacttggaggagacgcctgtggtgtttgaggacgtgacgctgcac
caggccaccatcctgcccaagaccgggaccgtgtccttggaagtgcggcttctagaggct
tcccacgcctttgaggtgtctgacagcaacggcagcctgatcgcaagcgggaaggtgtac
cagtgggagagccctgaccccaagctctttgacacccgggccgccgtggaccccgcggac
tccacggctgagttccgcctgagccagggcgacgtgtacaaggatctgcggctgcggggc
tatgactacgggcccttcttccagctcgtcctcgagagcgacctcgaagggaacaggggc
cgcctgcagtggaacgacagctgggtgagcttcctggacgccatgctgcacatgtccatc
ctggcccccggccagctcggcctgtacctgcccacacgtttcacctccatccgcatcgac
cccgtcacccaccggcagaagctgtacacgctgcaggacaccacccaagcggccgacgtg
gtggtggacaggaatctgaacacagtggtggctggaggcgccctcttcttgggggcccac
tcctcagtggccccacggcgaccccaggagcatctcaagcctatcctggagaagttctgc
ttcacaccccacgtggagagcgggtgcctggccgggaacacggccctgcaggaggagctg
cagctgtgcagggggctggcacaggcactgcagaccaaggtggcccagcaggggctgaag
atggtggtgcctgggctggacggtgcccaggccccccgggaggccccgcagcagagcctg
cctcggctgctggctgccgcctgccagctgcaactcaacgggaacctgcagctggaactg
ggccaggtgctggcccaggagaggcctctgctgtgtgatgaccccctgctcagcggcctc
ctcgacgccccggcactcaaggcgtgcgtggacaccgccctggagaacatggccagcccc
aagatgaaggtggtggaggtgctggctggtgacggccaactgtactcccgcatcccggcg
ctgctcaacacccagcccgtgatggatctggactacacggccactgaccgcaacccgcag
gccctggaggccgcccaggccaagctggagcagctccacgtgacccagggccagtgggac
cccgccaacccagcccctggcagcctgggcaaggctgacctcctggtgtgcaactgtgcc
ctggccaccctcggcgacccggctgtggctgttggcaacatggcagccaccctgaaggag
gggggcttcctgctgctgcacacgctgctcgcaggacaccccctcggggagatggtcggc
ttcctcacctcccctgagcaaggcggcaggcacctcctgagccaggaccagtgggagagc
ctgttcgctggggcgtccctgcacctggtggccctgaagaggtccttctacggctccgtg
ctcttcctgtgccgccagcagaccccacaggacagccccgtcttcctgtccgtggaagac
actagcttccgttgggtcgactcactgaaggacatcctggccgacgcctcctcccggccg
gtgtggctgatggctgtcggctgcagcacctcgggcgtcgtgggcatggtgaactgtctc
cgaaaagagcccggcggccaccgcattcggtgcgtcctggtgtccaacctcagcagcacg
tcgcccgcccctgagatgcacccgagctcctcggagctgcagaaggtgctgcagggggac
ctggtgatgaacgtctaccgggacggagcctggggggccttccgccacttcccgctggag
caggaccggccagagaagcagacggagcacgccttcgtaaacgtcctcagccggggggac
ctctcctccatccgctgggtctgctccccgctgcactacgccctgcccgcctcctgccag
gaccgcctctgcagtgtctattacacctccctcaacttccgagacgtcatgctggccacg
ggcaagctgtcccctgactccatcccaggaaagtggctcactcgagactgcatgctgggc
atggagttctccggccgagatgccagcggcaggcgcgtgatgggaatggtgcccgcggaa
ggcctggccacctctgttctgctgcttcagcacgccacctgggaggtgccctccacctgg
accctggaggaggcagcgtcggtgcccatcgtctacacgacggcctactactcgctggtg
gtgcgagggcgcatgcagcccggggagtcggtgctcatccactcgggctcgggcggcgtg
ggccaggccgccatcgccatcgccctcagccggggctgccgcgtcttcaccaccgtgggg
tcggccgagaagcgggcgtacctccaggccaggttcccccagctcgacgagacctgcttc
gccaactcccgcgacacgtcctttgagcagcacgtgctgcggcacacggccgggaagggt
gtcgacctggtcctgaactccctggcggaagagaagctgcaggccagcgtgcggtgtctg
gcccagcacggccgcttcctggaaatcggcaaattcgacctttccaacaaccacgccctg
ggcatggccgtcttcctgaagaatgtgaccttccacgggatcctgctggactcgctcttt
gaggagggcggcgccacctggcaggaggtgtcggagctgctgaaggcgggcatccaggag
ggcgtggtgcagccgctcaagtgcaccgtgttccccaggaccaaggtggaggccgccttc
cgctacatggcccagggcaagcacataggcaaagtggtcatccaggtgcgcgaggaggag
caggggccggcgccgcgcgggctgccgcccatcgcattgaccggcttgtccaagaccttc
tgccccccccacaagagctacgtcatcaccgggggcctgggcggcttcggcctgcagctg
gcgcagtggctccggctgcgaggggcccagaagctggtgctcacctcccgctcgggcatc
cgcacaggctaccaggccaggcaggtccgagagtggagacgccagggcgtccaggtcctg
gtgtccaccagcaacgccagctcgctggacggcgctcggagcctcatcactgaggccaca
cagcttgggcccgtgggaggcgtcttcaacctggccatggtcctgagagacgccgtgctg
gagaaccagaccccggagttcttccaggacgtcagtaagcccaagtacagcggcaccgcg
aacctggacagggtgacccgggaggcgtgtcccgagctggactacttcgtgatcttctcc
tccgtgagctgcgggcgcggcaatgccggccaggccaactacggcttcgccaactctgcc
atggagcgcatctgcgagaagcgccggcacgacgggctcccaggcctcgccgtgcagtgg
ggtgcgatcggcgacgtgggcgtcgtcctggagaccatgggcaccaacgacacggtcatc
ggcgggacgctgccccagcgcatcgcctcctgcctggaggtgctggatctcttcctgagc
cagccccaccccgtcctgagcagcttcgtcctggctgagaagaaggccgccgcccccagg
gacggcagcagccagaaggacctggtcaaggccgtggctcacatcctgggcatccgggac
gtggcctccatcaatccggacagcacgctggtggacctgggcctggactcgctcatgggc
gtggaggtgcgccagatactggagcgagagcacgacctggtgctgtccatgcgggaggtg
cggcagctcagcctccggaagctacaggaactctcctcgaagaccagcacggacgccgac
ccggcgactcccacatcccacgaggacagccctgtgcggcagcaggcaacgctgaacctg
agcaccctgctggtgaaccccgagggcccgaccttgacgcggctcaactccgtgcagagc
gcagagcggcccctgttcctggtccaccccatcgagggctccatcaccgtgttccacggc
ctggccgccaagctcagcatccccacctacggcctgcagtgcacgggagccgccccgctg
gacagcatccagagcctggcctcctactacatcgagtgcatcagacaggtgcagcccgag
gggccttaccgcatcgccggctactcttacggggcctgcgtggccttcgagatgtgctcg
cagctgcaggcccagcagagcgccacccccgggaaccacagcctcttcctgttcgacggc
tcacacaccttcgtgctggcctacacgcagagcgtccgcgctaagatgacccccggctgc
gaggccgaggccgaggccaaggccatgtacttcttcgtgcagcagttcaccgacatggag
caaggcaaggtgctggaggcgctgataccgctccagggcctggaggcgcgcgtggcggcc
accgtggacctgatcacgcagagccacgcgggcctggaccgccacgccctcagcttcgcc
gctcgctccttctaccagaagctgcgcgccgccgagaactactggccgcaggccacctac
cacggcaacgtgacgctgctgcgcgccaagacgggcggcgcctacggcgaggacctgggc
gccgactacaacctgtcgcaggtgtgcgacggcaaggtctcggtgcacgtcatcgagggc
gaccaccgcacgctgctggagggcagcggcctggagtccatcctcagcatcatccacagc
tgcctggccgagccgcgcgtcagcgtgcgggagggctag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (44)   
   KEGG COMPOUND (44)   
Chemical reaction (35)   
   KEGG ENZYME (1)   
   KEGG REACTION (34)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
3D Structure (2)   
   PDB (2)   
Protein domain (19)   
   Pfam (19)   
All databases (159)   

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