KEGG T01009: 448985

Sus scrofa (pig): 448985

Entry

448985            CDS       T01009

Symbol

CYP7A1

Name

(RefSeq) cholesterol 7-alpha-monooxygenase

K00489

cholesterol 7alpha-monooxygenase [EC:1.14.14.23]

Organism

ssc Sus scrofa (pig)

Pathway

ssc00120

Primary bile acid biosynthesis

ssc00140

Steroid hormone biosynthesis

ssc01100

Metabolic pathways

ssc03320

PPAR signaling pathway

ssc04976

Bile secretion

ssc04979

Cholesterol metabolism

Brite

KEGG Orthology (KO) [BR:ssc00001]
09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    448985 (CYP7A1)
   00140 Steroid hormone biosynthesis
    448985 (CYP7A1)
09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    448985 (CYP7A1)
  09154 Digestive system
   04976 Bile secretion
    448985 (CYP7A1)
   04979 Cholesterol metabolism
    448985 (CYP7A1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ssc00199]
    448985 (CYP7A1)
Enzymes [BR:ssc01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.23  cholesterol 7alpha-monooxygenase
     448985 (CYP7A1)
Cytochrome P450 [BR:ssc00199]
Cytochrome P450, animal type
  CYP7 family
   448985 (CYP7A1)

SSDB

Motif

Pfam:

p450

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

Position

4:74343101..74372628

AA seq 501 aa
MMSISLLGGIVTAVCCCLWLLLGMRRRQTGEPPLESGIIPYLGCALQFGANPLEFLRANQ
RKHGHIFTCQLMGNYVHFITNPLSYHKVLCHGKYLDWKKFHFTASAKAFGHRSIDPSDGN
TTDNINKTIIKTLQGDALNLLAAAMMENLQLVLRPQVAPQPEKPAWVTEGMYSFCYRVMF
EAGYVTLFGKDPIGHDAQKALILNNLDNFKQFDKIFPALVAGFPIHVFKTGHYAREKLAE
GLRLQKLRKRDHISELVRFLNDTLSTLDDAEKAKSLLAVLWASQANTIPATFWCLFQTIR
SPEAMKAASEEVNKTLEKAGQKISLDDKPIYLNQIELDSMPILDSIIKESLRLSSASLNI
RTAKEDFTLHLQDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTF
YSHGLKLKYYYMPFGSGATICPGRLFAVQEIKQFLILMLSYFDLELVESHVKCPPLDQSR
AGLGILPPSNDIEFRYKLKHL

NT seq 1506 nt +upstreamnt +downstreamnt
atgatgagcatatctttgcttggggggattgtgacagcagtgtgctgttgtttatggctt
cttcttggaatgaggagaaggcaaacgggcgaaccacctctggagagtgggataattccc
tatctgggttgtgcactgcaatttggtgccaatcctcttgagttcctccgagcaaaccaa
aggaaacatggtcacatttttacctgccaactcatgggaaactatgtccacttcatcaca
aatcccttgtcctaccataaagtgttgtgtcatggaaaataccttgactggaaaaaattt
cacttcactgcttctgcaaaggcatttgggcacagaagcattgaccccagtgatggaaat
accaccgataacataaataaaactatcatcaagaccctgcagggtgacgccttgaatttg
cttgccgcagccatgatggaaaacctccaacttgtcctgagaccccaggtggccccccaa
ccggagaagcccgcctgggtgacagagggcatgtattccttctgctaccgagtgatgttt
gaggctggctacgtcacgctctttggcaaagaccctatagggcacgatgcacagaaagca
ctcatcctaaacaaccttgacaacttcaagcagtttgacaagatctttccagccctggta
gcaggcttcccgattcatgtgttcaagacgggccactatgcccgggagaaactggctgag
ggcctgcggctccagaagctcagaaagagagaccacatctcggaactggtcaggtttctg
aatgataccctctccaccttagatgacgcagagaaagccaagtcgctcctcgctgtcctc
tgggcatcgcaagccaacaccattccggcgactttctggtgcttattccaaacgattagg
agccctgaagcaatgaaagcagcttctgaagaagtgaataaaacactggagaaggcgggc
caaaaaattagcttggacgataagcctatttatttgaatcaaatagaacttgacagcatg
cctatactagacagtatcatcaaggagtctctgaggctttccagcgcctccctcaacatc
cggactgctaaagaggatttcactttgcacctccaggacggatcctataacatccgaaaa
gatgacatcatagcgctttatccacaattaatgcacctggatccagaaatctacccagac
cctttgacttttaaatatgatcgctatcttgatgaaaatggaaagacaaagaccaccttc
tacagtcatggactcaagttaaagtattactatatgcccttcgggtcaggggctacgatc
tgtcctggaagattatttgctgtccaggaaatcaagcaatttttgattctgatgctttcc
tattttgacctggagctggtggagagccacgttaaatgtccccccttggaccagtcccgt
gcaggcttgggcattttaccaccatcaaatgatatcgagtttagatataaactcaaacat
ctgtga

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