KEGG   Sus scrofa (pig): 493186
Entry
493186            CDS       T01009                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04120  Ubiquitin mediated proteolysis
ssc04380  Osteoclast differentiation
ssc04630  JAK-STAT signaling pathway
ssc04668  TNF signaling pathway
ssc04910  Insulin signaling pathway
ssc04917  Prolactin signaling pathway
ssc04920  Adipocytokine signaling pathway
ssc04930  Type II diabetes mellitus
ssc04931  Insulin resistance
ssc04932  Non-alcoholic fatty liver disease
ssc04935  Growth hormone synthesis, secretion and action
ssc05160  Hepatitis C
ssc05164  Influenza A
ssc05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    493186 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    493186 (SOCS3)
   04668 TNF signaling pathway
    493186 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    493186 (SOCS3)
   04920 Adipocytokine signaling pathway
    493186 (SOCS3)
   04917 Prolactin signaling pathway
    493186 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    493186 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    493186 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    493186 (SOCS3)
   05164 Influenza A
    493186 (SOCS3)
   05168 Herpes simplex virus 1 infection
    493186 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    493186 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    493186 (SOCS3)
   04931 Insulin resistance
    493186 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ssc04121]
    493186 (SOCS3)
Ubiquitin system [BR:ssc04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul5 complex
    Target recognizing subunit
     493186 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 493186
NCBI-ProteinID: NP_001116668
UniProt: B1H0V9
Position
12:3643832..3647015
AA seq 229 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHLFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVRHYMPPSGAPSFSSPPTEPSSSPSSEVPEQPPAQPLPGGPPRRAYYIYSGGEKIPL
VLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 690 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgaccggcggcgaggcgaacctgctgctt
agcgccgagcccgcgggcaccttcctcatccgcgacagctcggaccagcgacacctcttc
acgctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctcgctgcagagtgacccccgcagcacgcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcgtcactacatgccaccctccggcgccccctccttctcctcgcctccg
actgaaccctcctcgtcgccctcctccgaggtgcccgagcagccgcccgcccagccgctc
ccggggggcccccctagaagagcctattacatctactccgggggcgagaagatccctctg
gtgttgagccggcccctctcctctaacgtggccactctccagcatctctgtcggaaaaca
gtcaacggccacctggactcctatgagaaagtcacccagctgcctgggcccattcgggag
ttcctggaccagtacgatgccccactttaa

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